from 01.01.2014 until now
Saratov, Saratov, Russian Federation
employee
Saratov, Saratov, Russian Federation
student
Saratov, Saratov, Russian Federation
employee
Saratov, Saratov, Russian Federation
UDK 616 Патология. Клиническая медицина
GRNTI 76.29 Клиническая медицина
OKSO 31.05.03 Стоматология
BBK 566 Стоматология
The subject of the study is the prospects of implementing the method of X-ray densitometry in preparation for dental implantation (DI) in patients with chronic kidney disease (CKD). The aim of the study was to determine the diagnostic significance of densitometry results (frequency and severity of BMD) in middle-aged patients with various stages of CKD and healthy controls when choosing a method of dental implantation. Methodology. We selected 203 ambulatory charts of middle-aged patients which underwent dual-energy X-ray absorptiometry (DXA) with DTX 200 densitometer (Denmark) on the basis of Saratov Regional Center of Osteoporosis Prevention and Treatment and osteoporosis centers. Results and discussion. The somatic pathology of the examined persons was represented by: diseases of cardiovascular system, kidney diseases, rheumatologic diseases, combination of cardiovascular diseases and kidney diseases and cardiovascular and rheumatologic diseases. Data on the periodontal status of those examined were unknown. Twelve groups of examinees were distinguished according to gender, glomerular filtration rate (GFR). Two other gender groups were patients on outpatient hemodialysis. BMD in CHD depends on patient's sex, somatic pathology and the nature of treatment, stage of the disease. As the disease severity increases, the number of patients with normal BMD decreases, the number of patients with low BMD increases, with osteopenia diagnosed in every third of both genders, and osteoporosis (OD) in every third man and every second woman. The pathology itself, regardless of the patient's gender, is of decisive importance in the development of a decreased BMD in patients with somatic pathology. It is important for MDI to distinguish forms of renal osteodystrophy (ROD), but X-ray densitometry cannot distinguish OP from several forms of ROD. Conclusions. In middle-aged individuals, X-ray densitometry should be performed as a mandatory examination for the timely detection of OP. For outpatient dental patients with CKD, we suggest not to test for MPCT by this method prior to MDI.
X-ray densitometry, dental implantation, chronic kidney disease, bone mineral density, middle-aged patients, somatic pathology, osteopenia, osteoporosis
1. Verbovoy A.F., Pashenceva A.V., Sharonova L.A. Osteoporoz: sovremennoe sostoyanie problemy. Terapevticheskiy arhiv. 2017;89(5):90 97. [Verbovoĭ A.F., Pashentseva A.V., Sharonova L.A. Osteoporosis: Current state of the art. Terapevticheskii Arkhiv. 2017;89(5):90 97. (In Russ.)].doi.org/10.17116/terarkh201789590-97
2. Dental'naya implantaciya. Nacional'noe rukovodstvo / pod red. Kulakova A. A. - Moskva: GEOTAR-Media, 2018:400. [Dental implantation / edited by Kulakov A.A. - Moscow: GEOTAR-Media, 2018:400. (in Russian)].https://www.rosmedlib.ru/book/ISBN9785970445419.html
3. Mel'nikov A.A., D'yachenko V.V., Shubin I.V., Nikitin A.E., Sozykin A.V., Averin E.E. Sovremennye podhody i vozmozhnosti ocenki mineral'noy plotnosti kostnoy tkani metodom kolichestvennoy komp'yuternoy tomografii (obzor literatury). Consilium Medicum. 2021; 23 (4): 372-381. [Melnikov A.A., Diachenko V.V., Shubin I.V., Nikitin A.E., Sozykin A.V., Averin E.E. Modern approaches and possibilities for assessing bone mineral density by quantitative computed tomography (literature review). Consilium Medicum. 2021; 23 (4): 372-381. (In Russ.)]. doi:https://doi.org/10.26442/20751753.2021.4.200643
4. Federal'nye klinicheskie rekomendacii po diagnostike, lecheniyu i profilaktike osteoporoza. Problemy endokrinologii. - 2017. [Russian clinical guidelines on the diagnostics, treatment, and prevention of osteoporosis. Problems of Endocrinology. 2017 (In Russ.)].
5. Federal'nye klinicheskie rekomendacii po diagnostike, lecheniyu i profilaktike osteoporoza. Osteoporoz i osteopatii. - 2021. [Federal clinical guidelines for diagnosis, treatment and prevention of osteoporosis. Osteoporosis and Bone Diseases. -2021 (In Russ.)].
6. Ferreira A.C., Cohen-Solal M., D'Haese P.C., Ferreira A. European Renal Osteodystrophy (EUROD), an initiative of the CKD-MBD working group of the ERA-EDTA. The Role of Bone Biopsy in the Management of CKD-MBD. Calcif Tissue Int. 2021;108(4):528-538. doi:https://doi.org/10.1007/s00223-021-00838-z. PMID: 33772341
7. Kanis J.A., Cooper C., Rizzoli R., Reginster J-Y. Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the Committees of Scientific Advisors and National Societies of the International Osteoporosis Foundation (IOF). Osteoporos Int. 2019;30(1):3-44. https://doi.org/10.1007/s00198-018-4704-5.
8. Miller P.D. Chronic kidney disease and the skeleton. Bone Res. 2014. doi:https://doi.org/10.1038/boneres.2014.44. PMID: 26273531
9. Pazianas M., Miller P.D. Osteoporosis and Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD): Back to Basics. 2021 Oct;78(4):582-589. doi:https://doi.org/10.1053/j.ajkd.2020.12.024. PMID: 33774081
10. Levey A.S., Greene T., Kusek J., Beck G. A simplified equation to predict glomerular filtration rate from serum creatinine. (abstract) // J Am Soc Nephrol. - 2000;11:155A. https://hero.epa.gov/hero/index.cfm/reference/details/reference_id/658418
