CLINICAL EFFICACY OF A METHOD FOR REPLACING BONE DEFECTS IN THE JAWS WITH THE POSSIBILITY OF TEMPORARY DENTAL PROSTHETICS FOR THE PERIOD OF INTEGRATION OF DENTAL IMPLANTS
Abstract and keywords
Abstract (English):
The article is devoted to the clinical testing of the developed protocol of dental implantation surgery, including guided bone regeneration and temporary prostheses, for patients with complete edentulism and atrophy of the alveolar bone. The clinical testing of the proposed prosthetics technology involved 24 patients aged 55 to 72 years with complete absence of teeth and atrophy of the jaw bones. All patients underwent surgery according to the developed protocol. At the same time, 18 patients underwent dental implantation on the lower jaw on the day of surgery for installation of an individual titanium mesh for guided bone regeneration with the possibility of temporary prosthetics. A total of 260 dental implants were installed, 144 in the upper jaw and 116 in the lower jaw. The meshes were loaded with temporary non-removable orthopedic structures on the day of surgery. The effectiveness of dental implantation was assessed using cone beam computed tomography and resonance frequency analysis on the day of installation, during temporary and permanent prosthetics, and one year after surgery. As a result of the conducted research, it was found that the average increase in bone tissue in height and width of the upper jaw was 4.3 and 4.1 mm, respectively, and the lower jaw was 3.8 and 4.1 mm. The high stability of dental implants was noted both immediately after installation and under conditions of functional load. The assessment of the quality of life of patients in the study group was carried out both before surgery and during the postoperative period of 14, 30, 90 and 180 days. The results of the study showed that temporary dental prosthetics using non-removable structures based on individual titanium meshes made using 3D printing technology significantly improves all parameters of the quality of life of patients with complete edentulism.

Keywords:
guided bone regeneration, individual titanium mesh, dental implantation, osseointegration, selective laser sintering, complete absence of teeth
References

1. Avetisyan Z.A., Stepanov A.G., Apresyan S.V., Kopylov M.V. Razrabotka konstrukcii individual'noy titanovoy membrany s elementami fiksacii vremennyh nes'emnyh zubnyh protezov. Rossiyskiy vestnik dental'noy implantologii. 2023;(1):18-24. [Avetisyan Z.A., Stepanov A.G., Apresyan S.V., Kopylov M.V. Design development of an individual titanium membrane with fixing elements for temporary fixed dentures. Rossijskij vestnik dentalʹnoj implantologii. 2023;(1):18-24. (In Russ.)].

2. Akkuzhin M.I., Amhadova M.A., Hamraev T.K. Planirovanie dental'noy implantacii v usloviyah deficita kostnoy tkani i profilaktika posleoperacionnyh oslozhneniy (obzor literatury). Medicinskiy alfavit. 2020;(23):9-15. [Akkuzhin M.I., Amkhadova M.A., Khamraev T.K. Planning of dental implantation in conditions of bone tissue deficiency and prevention of postoperative complications (literature review). Medical alphabet. 2020;(23):9-15. (In Russ.)]. https://doi.org/10.33667/2078-5631-2020-23-9-15

3. Apresyan S.V., Stepanov A.G., Antonik M.M., Degtyarev N.E., Kravec P.L., Lihnenko M.N. i dr. Kompleksnoe cifrovoe planirovanie stomatologicheskogo lecheniya. Moskva: Mozartika; 2020. 398 s. [Apresyan S.V., Stepanov A.G., Antonik M.M., Degtyarev N.E., Kravets P.L., Likhnenko M.N. et al. Integrated digital planning of dental treatment. Moscow: Mozartika; 2020. 398 p. (In Russ.)].

4. Bazikyan E.A., Smbatyan B.S. Vosstanovlenie kostnoy tkani metodom peresadki kostnyh blokov (chast' 2). Klinicheskaya stomatologiya. 2009;(1):44-52. [Bazikyan E.A., Smbatyan B.S. Restoration of bone tissue with the bone blocks transplantation (part 2). Clinical dentistry. 2009;(1):44-52. (In Russ.)]. https://elibrary.ru/item.asp?id=22796129&ysclid=m8o2moqn3o185533166

5. Ivanov S.Yu., Gazhva Yu.V., Muraev A.A., Bonarcev A. P. Ispol'zovanie membrannoy tehniki dlya napravlennoy regeneracii kostnoy tkani pri hirurgicheskih stomatologicheskih vmeshatel'stvah. Sovremennye problemy nauki i obrazovaniya. 2012;(3):74. [Ivanov S.Yu., Gazhva Yu.V., Muraev A.A., Bonartsev A.P. Contemporary membrane to guided bone regeneration in dental surgery (review). Modern problems of science and education. 2012;(3):74. (In Russ.)]. https://elibrary.ru/item.asp?id=17822314

6. Ivanov S.Yu., Muraev A.A., Yamurkova N.F. Rekonstruktivnaya hirurgiya al'veolyarnoy kosti. Moskva: GEOTAR-Media; 2016. 356 s. [Ivanov S.Yu., Muraev A.A., Yamurkova N.F. Reconstructive surgery of the alveolar bone. Moscow: GEOTAR-Media; 2016. 356 p. (In Russ.)].

7. Kulakov A.A., Gvetadze R.Sh., Braylovskaya T.V., Har'kova A.A., Dzikovickaya L.S. Sovremennye podhody k primeneniyu metoda dental'noy implantacii pri atrofii i defektah kostnoy tkani chelyustey. Stomatologiya. 2017;96(1):43-45. [Kulakov A.A., Gvetadze R.Sh., Braĭlovskaia T.V., Khar’kova A.A., Dzikovitskaya L.S. Modern approaches to dental implants placement in deficient alveolar bone. Stomatology. 2017;96(1):43-45. (In Russ.)]. https://doi.org/10.17116/stomat201796143-45

8. Kuri F. i dr. Regenerativnye metody v implantologii. Moskva: Azbuka; 2013. 514 s. [Kuri F. et al. Regenerative methods in implantology. Moscow: Azbuka; 2013. 514 p.]

9. Lomakin M.V., Filatova A.S., Soloschanskiy I.I. Napravlennaya kostnaya regeneraciya pri rekonstrukcii al'veolyarnogo kostnogo ob'ema v oblasti dental'noy implantacii. Rossiyskaya stomatologiya. 2011;4(5):15-18. [Lomakin M.V., Filatova A.S., Soloshchansky I.I. Guided bone regeneration in the reconstruction of the alveolar bone volume for dental implantation. Russian journal of stomatology. 2011;4(5):15-18. (In Russ.)]. https://elibrary.ru/item.asp?id=20809979&ysclid=m8o2bsuncc310170428

10. Muzykin M.I, Kokovihina E.V., Gerasimova E.A., Mischuk V.F., Iordanishvili A.K., Slesarev O.V. Vozrastnaya i postekstrakcionnaya atrofiya chelyustey i sovremennye vozmozhnosti vosstanovleniya zhevatel'nogo apparata u pozhilyh i staryh lyudey. Uspehi gerontologii. 2021;34(1):134-143. [Muzikin M.I., Kokovihina E.V., Gerasimova E.A., Mishchuk V.F., Iordanishvili A.K., Slesarev O.V. Age-related and post-extraction atrophy of the jaws and modern possibilities for restoring the masticatory apparatus in the elderly people. Advances in gerontology. 2021;34(1):134-143. (In Russ.)]. https://doi.org/10.37988/1811-153X_2023_4_29

11. Nalchadzhyan A.M., Muraev A.A., Bophoev S.V., Kazaryan G.G., Tunyan G.D., Martirosyan M.P. Napravlennaya kostnaya regeneraciya al'veolyarnoy chasti nizhney chelyusti s primeneniem individualizirovannoy titanovoy karkasnoy membrany: klinicheskiy sluchay. Klinicheskaya stomatologiya. 2024;26(4):29-33. [Nalchajyan A.M., Muraev A.A., Bophoev S.V., Kazaryan G.G., Tunyan G.D., Martirosyan M.P. Targeted bone regeneration of the alveolar part of the mandible using an individualized titanium skeleton membrane: a clinical case. Clinical dentistry. 2024;26(4):29-33. (In Russ.)]. https://doi.org/10.37988/1811-153X_2023_4_29

12. Popov N.V. Analiz oslozhneniĭ kompleksnogo lecheniya pacientov s defektami zubnyh ryadov v usloviyah atrofii kostnoĭ tkani chelyusteĭ. Institut Stomatologii. 2018;(2):66-67. [Popov N.V. Analysis of complications of complex treatment of patients with dentition defects in conditions of bone jaw atrophy. Institut stomatologii. 2018;(2):66-67. (In Russ.)]. https://elibrary.ru/item.asp?id=35340574&ysclid=m8o27zytru521349564

13. Stepanov A.G., Apresyan S.V. Cifrovye tehnologii v hirurgicheskoy stomatologii. Moskva: Mozartika; 2021. 125 s. [Stepanov A.G., Apresyan S.V. Digital technologies in surgical dentistry. Moscow: Mozartika; 2021. 125 p. (In Russ.)].

14. Stepanov A.G., Apresyan S.V., Grigoryanc L.A., Batov R.V. avtory; Federal'noe gosudarstvennoe avtonomnoe obrazovatel'noe uchrezhdenie vysshego obrazovaniya "Rossiyskiy universitet druzhby narodov" patentoobladatel'. Ustroystvo dlya vremennogo zubnogo protezirovaniya pacienta na period napravlennoy kostnoy regeneracii chelyustey. Rossiyskaya Federaciya patent RU 2748200. Opubl. 20.05.21. [Stepanov A.G., Apresyan S.V., Grigoryants L.A., Batov R.V. inventors; Federalnoe gosudarstvennoe avtonomnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Rossijskij universitet druzhby narodov" assignee. Device for temporary dental prosthetics in patient forperiod of directed bone regeneration of jaws. Russian Federation patent RU 2748200. Publ. 05/20/21. (In Russ.)]. https://elibrary.ru/item.asp?id=45812800&ysclid=m8o3lhp4x527123632

15. Stepanov A.G., Apresyan S.V., Dzhalalova M.V., Kopylov M.V., Avetisyan Z.A. avtory; Federal'noe gosudarstvennoe avtonomnoe obrazovatel'noe uchrezhdenie vysshego obrazovaniya "Rossiyskiy universitet druzhby narodov" patentoobladatel'. Sposob zamescheniya kostnyh defektov chelyustey s vozmozhnost'yu vremennogo zubnogo protezirovaniya na period integracii dental'nyh implantatov. Rossiyskaya Federaciya patent RU 2793523. Opubl. 04.04.2023. [Stepanov A.G., Apresyan S.V., Jalalova M.V., Kopylov M.V., Avetisyan Z.A. Method forreplacing bone defects in thejawswith thepossibility of temporary dental prosthetics for the period of dental implants integration. Russian Federation patent RU 2793523. Publ. 04/04/2023. (In Russ.)]. https://elibrary.ru/item.asp?id=53730305&ysclid=m8o343l1eu966529351

16. Ciciashvili A.M., Panin A.M., Lepilin A.V., Chuvilkin V.I., Ahmedov G.D. Hirurgicheskoe lechenie pacientov s ispol'zovaniem implantatov pri chastichnom otsutstvii zubov v usloviyah deficita kostnoy tkani. Stomatologiya. 2019;98(1):30‑33. [Tsitsiashvili A.M., Panin A.M., Lepilin A.V., Chuvilkin V.I., Akhmedov G.D. Implant surgery in partially edentulous patients with alveolar bone deficiency. Stomatology. 2019;98(1):30‑33. (In Russ.)]. https://doi.org/10.17116/stomat20199801130

17. Ackland D.C., Robinson D., Redhead M., Lee P.V.S., Moskaljuk A., Dimitroulis G. A personalized 3D-printed prosthetic joint replacement for the human temporomandibular joint: From implant design to implantation. Journal of the mechanical behavior of biomedical materials. 2017;69:404-411. https://doi.org/10.1016/j.jmbbm.2017.01.048

18. Pieri F., Corinaldesi G., Fini M., Aldini N.N., Giardino R., Marchetti C. Alveolar ridge augmentation with titanium mesh and a combination of autogenous bone and anorganic bovine bone: a 2-year prospective study. Journal of periodontology. 2008;79(11):2093-2103. https://doi.org/10.1902/jop.2008.080061

19. Caffesse R.G., Nasjleti C.E., Morrison E.C., Sanchez R. Guided tissue regeneration: comparison of bioabsorbable and non-bioabsorbable membranes. Histologic and histometric study in dogs. Journal of periodontology. 1994;65(6):583-591. https://doi.org/10.1902/jop.1994.65.6.583

20. Carrel J.P., Wiskott A., Scherrer S., Durual S. Large bone vertical augmentation using a three-dimensional printed tcp/ha bone graft: a pilot study in dog mandible. Clinical implant dentistry and related research. 2016;18(6):1183-1192. https://doi.org/10.1111/cid.12394

21. Esposito M., Grusovin M. G., Felice P., Karatzopoulos G., Worthington H.V., Coulthard P. The efficacy of horizontal and vertical bone augmentation procedures for dental implants - a cochrane systematic review. European journal of oral implantology. 2009;2(3):167-184.

22. Raikar S., Talukdar P., Kumari S., Panda S.K., Oommen V.M., Prasad A. Factors affecting the survival rate of dental implants: A retrospective study. Journal of international society of preventive and community dentistry. 2017;7(6):351-355. https://doi.org/10.4103/jispcd.JISPCD_380_17

23. Pauletto P., Ruales-Carrera E., Mezzomo L.A., Stefani C.M., Taba M. Jr., Gonçalves R.B. et al. Clinical performance of short versus standard dental implants in vertically augmented bone: An overview of systematic reviews. Clinical oral investigations. 2021;25(11):6045-6068. https://doi.org/10.1007/s00784-021-04095-0


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