Abstract (English):
The aim of the systematic review was to search and analyze publications on prospective areas of chewing gum use (including hygienic oral care, diagnostic potential and complex treatment of diseases and conditions of the dental profile) in dentistry as well as in gastroenterology and cognitive psychology. Materials and methods of research. The review presents the results of the materials analysis from the original full-text articles, systematic reviews and meta-analysis (with analysis of cited references) in Russian and English, reflecting various therapeutic and preventive areas of chewing gum use in patients with various dental and systemic diseases; abstracts of reports were not be analysed. Information sources. Electronic databases eLibrary, Cyberlenika, MEDLINE, PubMed, Scopus, Web of Science, Cochrane Library. The results of the research and discussion. According to the specified requirements, at the first stage 481 publications were selected and analyzed; the search depth is up to 35 years. After the screening the material, taking into account the keywords specification, 132 publications were selected, including meta-analyses. Conclusions. Various therapeutic and prophylactic directions of the chewing gum use in patients with various dental and systemic diseases were presented; The authors generalized position of publications is that the main condition for classifying chewing gum as an oral hygiene product is the absence of sugar in it and the presence of ingredients that determine therapeutic and prophylactic effects specifically: cleansing, anti-carious, anti-inflammatory, deodorizing effect, stimulation of salivation; specific effects (due to the introduction of therapeutic and prophylactic additives into chewing gums); stimulation of blood circulation in the tissues of the mucoparodontal complex; positive effect on cognitive activity, on the mood of the individual, on concentration of attention; reduction of esophageal reflux symptoms.

Keywords:
chewing gum, chewing, oral hygiene products, oral fluid, oral microflora, dental caries, periodontal diseases and oral mucosa, xerostomia, polypharmacy, halitosis, systemic pathology, cognitive functions, digestion

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