Ufa, Russian Federation
Ufa, Ufa, Russian Federation
from 01.01.2018 until now
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
from 01.01.2004 until now
Ufa, Ufa, Russian Federation
from 01.01.1983 until now
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
UDK 616 Патология. Клиническая медицина
Objectives. Studying the characteristics of oral fluid in people of different age groups and different health conditions: healthy children, children with chronic renal failure, with cerebral palsy, with congenital cleft palate, healthy adults, elderly and senile people, pregnant women. Purpose. To evaluate the influence of somatic pathology and age-related characteristics on parametric biochemical parameters of oral fluid: calcium, magnesium, phosphorus, protein. Methodology. The examination of patients and the collection of material were carried out at the clinical base of the Department of Pediatric Dentistry and Orthodontics with the course of IDPO of the Bashkir State Medical University (head of the department, Doctor of Medical Sciences, Professor S.V. Chuikin). An analysis of oral fluid was carried out in people of different age groups and different health conditions: healthy children, children with chronic renal failure, with cerebral palsy, with congenital cleft palate, healthy adults, elderly and senile people, pregnant women with physiological pregnancy and with edema. Results. Data were obtained on the level of biochemical parameters of oral fluid in people of different age groups and different health conditions: healthy children, children with chronic renal failure, with cerebral palsy, with congenital cleft palate, healthy adults, elderly and senile people, pregnant women. Conclusions. The biochemical composition of oral fluid changes in the presence of somatic pathology, during pregnancy and at different age periods. The dynamics of biochemical parameters of oral fluid can be a diagnostic marker for identifying diseases and allows us to evaluate the effectiveness of therapy.
biochemistry of oral fluid, calcium, magnesium, phosphorus, protein, concomitant diseases, different age groups
1. Aleksandrova O.A., Vinnichenko Yu.A. Dinamika osnovnyh biohimicheskih pokazateley rotovoy zhidkosti u detey s osteosarkomoy i sarkomoy Yuinga na fone sistemnogo himioterapevticheskogo lecheniya. Stomatologiya. 2018;97;6(2):22. [O.A. Aleksandrova, Yu.A. Vinnichenko. Dynamics of the main biochemical parameters of oral fluid in children with osteosarcoma and Ewing's sarcoma during systemic chemotherapy treatment. Dentistry. 2018;97;6(2):22. (In Russ.)]. https://www.elibrary.ru/item.asp?id=36893728
2. Galeeva R.R., Chuykin S.V. Klinicheskie rezul'taty stomatologicheskogo obsledovaniya detey s detskim cerebral'nym paralichom. Ural'skiy medicinskiy zhurnal. 2014;3(117):36-38. [R.R. Galeeva, S.V. Chuikin. Clinical results of dental examination of children with cerebral palsy. Ural Medical Journal. 2014;3(117):36-38. (In Russ.)]. https://elibrary.ru/item.asp?id=21531277
3. Gromova S.N., Elikov A.V., Ogorodova N.Yu., Pyshkina O.A., Gromov Ya.P., Guzhavina N.A., Koledaeva A.K. Opyt ocenki gigienicheskoy effektivnosti zubnyh past po biohimicheskim parametram rotovoy zhidkosti. Stomatologiya detskogo vozrasta i profilaktika. 2022;22;2(82):133-142. [S.N. Gromova, A.V. Elikov, N.Yu. Ogorodova, O.A. Pyshkina, Ya.P. Gromov, N.A. Guzhavina, A.K. Koledaeva. Experience in assessing the hygienic effectiveness of toothpastes based on the biochemical parameters of oral fluid. Pediatric dentistry and prevention. 2022;22;2(82):133-142. (In Russ.)]. DOIhttps://doi.org/10.33925/1683-3031-2022-22-2-133-142.
4. Mitronin A.V., Antonova O.A. Biomarkery smeshannoy slyuny kak indikatory sostoyaniya organizma. Rossiyskaya stomatologiya. 2022;15(1):61-62. [A.V. Mitronin, O.A. Antonova. Biomarkers of mixed saliva as indicators of the state of the body. Russian dentistry. 2022;15(1):61-62. (In Russ.)]. DOIhttps://doi.org/10.17116/rosstomat20221501125.
5. Pohoden'ko-Chudakova I.O., Surin A.V. Biohimicheskie pokazateli zhidkostnyh sred organizma kak ocenka statusa i ego dinamiki pri hronicheskom sinusite verhnechelyustnoy pazuhi. Analiticheskiy obzor literatury. Stomatologiya. Estetika. Innovacii. 2018;2(3):385-394. [I.O. Pokhodenko-Chudakova, A.V. Surin. Biochemical indicators of body fluids as an assessment of the status and its dynamics in chronic sinusitis of the maxillary sinus. Analytical review of the literature. Dentistry. Aesthetics. Innovation. 2018;2(3):385-394. (In Russ.)]. https://www.elibrary.ru/item.asp?id=35740741
6. Rozhko O.P., Den'ga O.V., Levickiy A.P. Biohimicheskie Pokazateli rotovoy zhidkosti u detey s diffuznym netoksicheskim zobom v processe profilaktiki osnovnyh stomatologicheskih zabolevaniy. Vestnik stomatologii. 2015;1(90):88-91. [O.P. Rozhko, O.V. Denga, A.P. Levitsky. Biochemical indicators of oral fluid in children with diffuse non-toxic goiter in the process of preventing major dental diseases. Bulletin of Dentistry. 2015;1(90):88-91. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25933520
7. Hripach L.V., Knyazeva T.D., Zheleznyak E.V., Makoveckaya A.K., Koganova Z.I., Budarina O.V., Lebedeva N.V., Ingel' F.I., Demina N.N. Adaptivnye izmeneniya biohimicheskih i immunologicheskih pokazateley smeshannoy slyuny pri vozdeystvii zagryazneniy atmosfernogo vozduha na detey doshkol'nogo vozrasta. Mezhdunarodnyy zhurnal prikladnyh i fundamental'nyh issledovaniy. 2019;6:68-73. [L.V. Khripach, T.D. Knyazeva, E.V. Zheleznyak, A.K. Makovetskaya, Z.I. Koganova, O.V. Budarina, N.V. Lebedeva, F.I. Ingel, N.N. Demina. Adaptive changes in biochemical and immunological parameters of mixed saliva under the influence of atmospheric air pollution on preschool children. International Journal of Applied and Basic Research. 2019;6:68-73. (In Russ.)]. https://www.elibrary.ru/item.asp?id=38489006
8. Abramyan S.V., Arzhancev A.P., Arutyunov A.S. i dr. Chelyustno-licevaya hirurgiya. Nacional'noe rukovodstvo. Moskva : Obschestvo s ogranichennoy otvetstvennost'yu Izdatel'skaya gruppa "GEOTAR-Media". 2019:692. [S.V. Abramyan, A.P. Arzhantsev, A.S. Arutyunov et al. Maxillofacial surgery. National guidelines. Moscow : Limited Liability Company Publishing Group "GEOTAR-Media". 2019:692. (In Russ.)]. https://profbook.com.ua/index.php?route=product/product/download&product_id=4597&download_id=1308
9. Chuykin S.V., Shtan'ko M.I. Nekotorye fiziko-himicheskie i biohimicheskie pokazateli rotovoy zhidkosti u lic pozhilogo i starcheskogo vozrasta. Institut stomatologii. 2013;2(59):72-73. [S.V. Chuikin, M.I. Shtanko. Some physicochemical and biochemical indicators of oral fluid in elderly and senile people. Institute of Dentistry. 2013;2(59):72-73. (In Russ.)]. https://elibrary.ru/item.asp?id=22134651
10. Chuykin S.V., Kudashkina N.V., Akat'eva G.G., Chuykin O.S., Makusheva N.V., Egorova E.G., Maganova Z.Sh., Kuchuk K.N. Izmeneniya fiziko-himicheskih i biohimicheskih pokazateley rotovoy zhidkosti pri mestnom lechenii gingivita u beremennyh zhenschin s gestozom. Problemy stomatologii. 2021;17(1):76-82. [S.V. Chuikin, N.V. Kudashkina, G.G. Akatieva, O.S. Chuikin, N.V. Makusheva, E.G. Egorova, Z.Sh. Maganova, K.N. Kuchuk. Changes in physicochemical and biochemical parameters of oral fluid during local treatment of gingivitis in pregnant women with preeclampsia. Actual problems in dentistry. 2021;17(1):76-82. (In Russ.)]. DOIhttps://doi.org/10.18481/2077-7566-20-17-1-76-82.
11. Chuykin O.S., Kuchuk K.N., Chuykin S.V., Mochalov K.S., Davletshin N.A., Akat'eva G.G., Makusheva N.V., Ganieva R.A. Immunologicheskie, fiziko-himicheskie i biohimicheskie pokazateli rotovoy zhidkosti u detey s vrozhdennoy rasschelinoy neba i posleoperacionnym defektom neba. Problemy stomatologii. 2022;18(1):121-129. [O.S. Chuikin, K.N. Kuchuk, S.V. Chuikin, K.S. Mochalov, N.A. Davletshin, G.G. Akatieva, N.V. Makusheva, R.A. Ganieva. Immunological, physicochemical and biochemical parameters of oral fluid in children with congenital cleft palate and postoperative palate defect. Actual problems in dentistry. 2022;18(1):121-129. (In Russ.)]. DOIhttps://doi.org/10.18481/2077-7566-22-18-1-121-129.
12. Shevchenko O.V. Vliyanie izbytochnoy massy tela na stomatologicheskiy status i biohimicheskie parametry rotovoy zhidkosti. Stomatologiya. 2023;102(2):16-20. [O.V. Shevchenko. The influence of excess body weight on dental status and biochemical parameters of oral fluid. Dentistry. 2023;102(2):16-20. (In Russ.)]. DOIhttps://doi.org/10.17116/stomat202310202116
13. Shevchenko O.L., Antonova A.A. Sostav smeshannoy slyuny i pokazateli kariesa vremennyh zubov i ego oslozhneniy u detey. Endodontiya Today. 2015;4:8-11. [O.L. Shevchenko, A.A. Antonova. The composition of mixed saliva and indicators of caries in deciduous teeth and its complications in children. Endodontics Today. 2015;4:8-11. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25411139
14. Kuriakose S., Sundaresan C., Mathai V. et al. A comparative study of salivary buffering capacity, flow rate, resting pH, and salivary immunoglobulin A in children with rampant caries and caries-resistant children // J Indian Soc Pedod Prev Dent. - 2013;31(2):69-73. DOIhttps://doi.org/10.4103/0970-4388.115697.
15. Kubala E., Strzelecka P., Grzegocka M. et al. A review of selected studies that determine the physical and chemical properties of saliva in the field of dental treatment // BioMed Research International. - 2018;ID6572381:13. DOIhttps://doi.org/10.1155/2018/6572381 Hemadi A.S., Huang R., Zhou Y., Zou J. Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment // Int J Oral Sci. - 2017;9(11):e1. DOIhttps://doi.org/10.1038/ijos.2017.35