Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
The article presents the results of studying the degree of mineralization of the peripulpal dentin in healthy children and in children with osteogenesis imperfecta according to the data of cone beam computed tomography. In teeth with malformations of heavy tissue tissues, in particular with imperfect osteogenesis, pathological changes are noted in the special enamel and dentin involved in teeth and root canals. The study of the observed characteristics of the distribution of peripulpal dentin in dangerous intact teeth and teeth with malformations of hard dental tissues is of great interest. Subject. Of the study is the degree of mineralization of the peripulpal dentin in permanent intact teeth in healthy children and in children with osteogenesis imperfecta. Objectives. The degree of mineralization of periculpar dentin in children with osteogenesis imperfecta and in healthy peers in permanent intact teeth according to cone-beam computed tomography. Methodology. The study was performed at the Department of Pediatric Dentistry and at the Department of Radiation Diagnostics of the Moscow State Medical University named after A.I. Evdokimov in the Department of X-ray and Radiation Diagnostics of the CCCHLPHIS Clinic of the Moscow State Medical University named after A.I. Evdokimov. The study involved 22 patients aged 7 to 14 years. Results. In the group of children with imperfect osteogenesis in permanent molars with completed root formation, obliteration of the tooth cavity and wide root canals are noted. In the group of healthy children with permanent intact molars, no expansion of the tooth cavity and root canals was noted, no signs of root canal obliteration were detected. The average density of dentin in permanent molars in the group of healthy children is significantly higher than in children suffering from osteogenesis imperfecta. Conclusions. Cone-beam computed tomography is an objective method of visualizing the teeth of both jaws, which allows with minimal radiation load and high accuracy to determine the density of periculpar dentin in permanent teeth in children in one study. Pronounced violations of the mineralization of hard tissues of teeth in children with osteogenesis imperfecta and require further study as the child grows up at the stages of dental rehabilitation.
osteogenesis imperfecta, mineralization of hard dental tissues, density of periculpar dentin, cone-beam computed tomography
1. Lezhnev D.A., Kisel'nikova L.P., Shevchenko M.A., Sangaeva L.M. Ispol'zovanie metoda densitometrii dlya diagnostiki i povysheniya effektivnosti lecheniya kariesa postoyannyh zubov u detey s nezakonchennymi processami mineralizacii tverdyh tkaney. Radiologiya-praktika. 2012;4:35-40. [D.A. Lezhnev, L.P. Kiselnikova, M.A. Shevchenko, L.M. Sangaeva. The use of the densitometry method for the diagnosis and improvement of the effectiveness of the treatment of caries of permanent teeth in children with incomplete processes of mineralization of hard tissues. Radiology-practice. 2012;4:35-40. (In Russ.)]. https://www.elibrary.ru/item.asp?id=18258508
2. Kisel'nikova L.P., Lezhnev D.A., Shevchenko M.A. Izuchenie stepeni mineralizacii dentina v postoyannyh zubah u detey i vzroslyh. Stomatologiya dlya vseh. 2011;2:4-6. [L.P. Kiselnikova, D.A. Lezhnev, M.A. Shevchenko. Study of the degree of mineralization of dentin in permanent teeth in children and adults. Dentistry for everyone. 2011;2:4-6. (In Russ.)]. https://www.elibrary.ru/item.asp?id=16904137
3. Leont'ev V.K., Kisel'nikova L.P. Detskaya terapevticheskaya stomatologiya. Nacional'noe rukovodstvo. 2017:950. [V.K. Leont'ev, L.P. Kisel'nikova. Children's therapeutic dentistry. National guide. 2017:950. (In Russ.)]. https://medknigaservis.ru/wp-content/uploads/2018/12/Q0008781.pdf.
4. Avraamova O.G., Zaborskaya A.R. Vliyanie profilakticheskih meropriyatiy na sozrevanie emali zubov u detey (obzor literatury). Stomatologiya detskogo vozrasta i profilaktika. 2015;14(4(55)):3-7. [O.G. Avraamova, A.R. Zaborskaya. The effect of preventive measures on the maturation of tooth enamel in children (literature review). Pediatric dentistry and prevention. 2015;14(4(55)):3-7. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25373519
5. Lezhnev D.A., Vislobokova E.V., Kiselnikova L.P., Sholohova N.A., Smyslenova M.V., Truten V.P. Analysis of mineral density of calcified tissues in children with XLHR and hypophosphatasia using cone-beam computed tomography dat // International Journal of Biomedicine. - 2021;11(1):53-57. http://dx.doi.org/10.21103/Article11(1)_OA11
6. Shevchenko M.A., Kisel'nikova L.P., Petrova O.I. Primenenie metoda ozonirovaniya pri lechenii kariesa dentina v postoyannyh zubah u detey. Stomatologiya detskogo vozrasta i profilaktika. 2020;20(1):55-58. [M.A. Shevchenko, L.P. Kiselnikova, O.I. Petrova. Application of the ozonation method in the treatment of dentin caries in permanent teeth in children. Pediatric dentistry and prevention. 2020;20(1):55-58. (In Russ.)]. https://doi.org/10.33925/1683-3031-2020-20-1-55-58
7. Nadyrshina D.D., Husainova R.I., Husnutdinova E.K. Sovremennoe sostoyanie kliniko-geneticheskih aspektov nesovershennogo osteogeneza. Medicinskaya genetika. 2010;9(3):3-11.2. [D.D. Nadyrshina, R.I. Khusainova, E.K. Khusnutdinova. The current state of clinical and genetic aspects of osteogenesis imperfecta. Medical genetics. 2010;9(3):3-11.2. (In Russ.)]. https://www.elibrary.ru/item.asp?id=16346296
8. Kuz'mina E.M., Yanushevich O.O., Kuz'mina I.N., Lapatina A.V. Tendencii rasprostranennosti i intensivnosti kariesa zubov sredi naseleniya Rossii za 20-letniy period. Dental Forum. 2020;3(78):2-8.1.1. [E.M. Kuzmina, O.O. Yanushevich, I.N. Kuzmina, A.V. Lapatina. Trends in the prevalence and intensity of dental caries among the population of Russia over a 20-year period. Dental Forum. 2020;3(78):2-8.1.1. (In Russ.)]. https://www.elibrary.ru/item.asp?id=43825063
9. Cymlyanskaya V.V. Stomatologicheskie proyavleniya nesovershennogo osteogeneza. Rossiyskiy vestnik perinatologii i pediatrii. 2018;63(4):300-301. [V.V. Tsymlyanskaya. Dental manifestations of osteogenesis imperfecta. Russian Bulletin of Perinatology and Pediatrics. 2018;63(4):300-301. (In Russ.)]. https://www.elibrary.ru/item.asp?id=35510571
10. Yahyaeva G.T Namazova-Baranova L.S, Margieva T.V, Chumakova O.V. Nesovershennyy osteogenez u detey v Rossiyskoy Federacii: rezul'taty audita Federal'nogo registra. Pediatricheskaya farmakologiya. 2016;13.3(1):44-48. [G.T. Yakhyaeva, L.S. Namazova-Baranova, T.V. Margieva, O.V. Chumakova. Osteogenesis imperfecta in children in the Russian Federation: results of the audit of the Federal Register. Pediatric pharmacology. 2016;13.3(1):44-48. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25453993
11. Mejàre I., Axelsson S., Dahlën G.A. et al. Caries risk assessment. A systematic review // Acta Odontologica Scandinavica. - 2014;72(2):81-91.2.1. doi:https://doi.org/10.3109/00016357.2013.822548.
12. Alves L.S., Zenkner J.E.A., Wagner M.B. et al. Eruption stage of permanent molars and occlusal caries activity/arrest // Journal of dental research. - 2014;93(7):114S-119S.3.1. doi:https://doi.org/10.1177/0022034514537646.
13. Lindahl K., Åström E., Rubin C.J., Grigelioniene G., Malmgren B., Ljunggren Ö., Kindmark A. Genetic epidemiology, prevalence, and genotype-phenotype correlations in the Swedish population with osteogenesis imperfecta // Eur J Hum Genet. - 2015;23(8):1042-1050. doi:https://doi.org/10.1038/ejhg.2015.81.
14. Martin E., Shapiro J.R. Osteogenesis imperfecta: Epidemiology and pathophysiology // Current Osteoporosis Reports. - 2007;5(3):91-97. doi:https://doi.org/10.1007/s11914-007-0023-z.