from 01.01.2008 until now
Nizhny Novgorod State Medical Academy of Ministry of Health of the Russian Federation (kafedra ortopedicheskoy stomatologii i ortodontii, docent)
from 01.01.2008 until now
Nizhniy Novgorod, Russian Federation
Nizhniy Novgorod, Russian Federation
Nizhniy Novgorod, Russian Federation
Nizhniy Novgorod, Russian Federation
Nizhniy Novgorod, Nizhny Novgorod, Russian Federation
Subject. Currently, about 530 types of microorganisms that live in supragingival and subgingival plaque have been discovered. To periodontal pathogens today carry a little more than ten types. The main role in the occurrence of periodontal disease is played by microorganisms included in the “red complex” of BANA+: Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia. With the simultaneous identification of these types can be judged on the high risk of developing periodontal disease. Objective ― calculating the frequency of occurrence of various types of dentition defects of patients with varying severity of periodontal disease, establishing the connection between the severity of periodontal disease and the number of periodontal pathogenic microflora. Methodology. A clinical examination of a patients group which consists of 32 women and 10 men in the age from 38 to 66 years was conducted. Anamnesis was collected using a survey and a special questionnaire. External examination and examination of the oral cavity allowed to find the clinical conditions and anatomical features that leads to periodontal disease’s development. Results. Based on the data of clinical and radiological examination, the patients were divided into three groups according to the severity of periodontal disease. During the clinical examination, we calculated the frequency of occurrence of various types of dentition defects in patients with varying degrees of severity of periodontal disease. Findings. It has been found that the course of chronic generalized periodontitis depends on the number of types of aggressive forms of periodontal pathogens.
periodontitis, periodontopathogenic microflora, PCR-diagnostics, planning of orthopedic treatment
1. Gasanova, L. R., Lukina, G. I., Bazikyan, E. A., Chunihin, A. A. (2016). Mikrobiologicheskij status polosti rta pacientov s hronicheskoj obstruktivnoj bolezn'yu legkih Oral microbiological status of patients with chronic obstructive pulmonary disease. Dental Forum Dental Forum, 1, 28-31. (In Russ.)
2. Grudjanov, A. I. (2009). Zabolevanija parodonta [Periodontal diseases]. Moscow : Med. inform. agentstvo, 336.
3. Zhulev, E. N. (2012). Ortopedicheskaya stomatologiya Prosthetic dentistry Moscow : Med. inform. agentstvo, 840.
4. Zhulev, E. N., Shchepetnova, E. E., Saakyan, M. Yu., Gabysheva-Hlustikova, S. Yu., Demin, D. N. (2012) Osobennosti ortopedicheskogo lecheniya hronicheskogo generalizovannogo parodontita Features of orthopedic treatment of chronic generalized periodontitis. Maestro stomatologii Maestro dentistry, 46, 48-51. (In Russ.)
5. Loktionov, A. L., Konoplya, A. I., Lunev, M. A., Karaulov A. V. (2015). Immunnye i oksidantnye narusheniya v patogeneze vospalitel'nyh zabolevanij parodonta Immune and oxidative disorders in the pathogenesis of inflammatory periodontal diseases Immunologiya Immunology, 5, 319-328. (In Russ.)
6. Eds. Lamont, Dzh., Leont'ev, V. K. (2010). Mikrobiologiya i immunologiya dlya stomatologov [Microbiology and immunology for dentists]. Moscow : Prakticheskaya medicina, 504. (In Russ.)
7. Mustakimova, R. F., Saleeva, G. T. (2014) Komp'yuternaya tomografiya v diagnostike zabolevanij parodonta [Computed tomography in the diagnosis of periodontal diseases]. Zdorov'e cheloveka v XXI veke [Human health in the XXI century], 192-194. (In Russ.)
8. Mustakimova, R. F., Saleeva, G. T. (2013). Rol' funkcional'nyh metodov issledovaniya v kompleksnoj diagnostike zabolevaniyah parodonta The role of functional research methods in the complex diagnosis of periodontal diseases Prakticheskaya medicina Practical medicine, 4, 75-77. (In Russ.)
9. Orekhova, L. Yu., Atrushkevich, V. G., Mihal'chenko, D. V., Gorbacheva, I. A., Lapina, N. V. (2017). Stomatologicheskoe zdorov'e i polimorbidnost': analiz sovremennyh podhodov k lecheniyu stomatologicheskih zabolevanij [Dental health and polymorbidity: an analysis of modern approaches to the treatment of dental diseases]. Parodontologiya [Parodontologiya], 3, 15-17. (In Russ.)
10. Orlova, O. G., Punchenko, O. E. (2014). Vyyavlenie parodontopatogennyh mikroorganizmov u zdorovyh nositelej s pomoshch'yu molekulyarno-biologicheskih metodov Detection of periodontal pathogenic microorganisms in healthy carriers using molecular biological methods Molekulyarnaya diagnostika Molecular Diagnostics, 1, 259. (In Russ.)
11. Yanushevich, O. O. (2018). Parodontologiya. Nacional'noe rukovodstvo Periodontology. The National guidebook Moscow : GEOTAR-Media, 752. (In Russ.)
12. Saakyan, M. Yu. (2017). Razrabotka i vnedrenie integrativnogo podhoda k planirovaniyu i ortopedicheskomu lecheniyu generalizovannyh zabolevanij parodonta Development and implementation of an integrative approach to planning and orthopedic treatment of generalized periodontal diseases avtoreferat diss. cand. med. science].Tver. (In Russ.)
13. Serova, N. V., Orekhova, L. Yu., Chibisova, M. Yu. (2013). Kliniko-luchevaya harakteristika hronicheskogo generalizovannogo parodontita [Clinical and radiation characteristics of chronic generalized periodontitis]. Parodontologiya [Periodontology], 3, 3-9. (In Russ.)
14. Starostina, T. N., Ahtyamova, G. R., Suvorova, P. G., Homutova, Yu. A., Yatkevich, A. O., Kudinova, E. V., Shavkunov, S. A. (2014). Mikroflora rta i patologiya parodonta Mouth microflora and periodontal pathology. Molekulyarnaya diagnostika Molecular Diagnostics, 1, 260. (In Russ.)
15. Haraeva, Z. F., Mustafaev, M. Sh., Zhanimova, L. R. (2014). Osobennosti mikroflory pacientov s parodontitom raznoj stepeni tyazhesti, vyyavlennye pri pomoshchi PCR metoda [Features of the microflora of patients with periodontitis of varying severity, identified using the PCR method]. Molekulyarnaya diagnostika [Molecular Diagnostics], 1, 258-259. (In Russ.)
16. Bazarnyj, V. V., Polushina, L. G., Maksimova, A. Yu., Svetlakova, E. N., Mandra, Yu. V. (2018). Citologicheskaya harakteristika bukkal'nogo epiteliya pri hronicheskom generalizovannom parodontite [Cytological characteristics of buccal epithelium in chronic generalized periodontitis]. Klinicheskaya laboratornaya diagnostika [Clinical laboratory diagnostics], 12 (63), 773-776. (In Russ.)
17. Yanushevich, O. O., Atrushkevich, V. G., Ajvazova, R. A., Sokolova, E. Yu. (2017). Mikrobiologicheskaya ocenka effektivnosti metoda lokal'noj dostavki antisepticheskih sredstv v terapii hronicheskogo generalizovannogo parodontita [Microbiological evaluation of the effectiveness of the method of local delivery of antiseptics in the treatment of chronic generalized periodontitis]. Kafedra. Stomatologicheskoe obrazovanie [Department. Dental education], 58, 18-21. (In Russ.)
18. Bascones, M. A., Figuero, R. E. (2005). Periodontal diseases a bacterial infection. Avances en periodon Implantol, 17, 3, 111-118.
19. Basic, A., Dahlén, G. (2015). Hydrogen sulfide production from subgingival plaque samples. Anaerobe, 35, A, 21-27.
20. Khan, Shams Tabrez et al. (2013). Comparative effectiveness of NiCl2, Ni- and NiO-NPs in controlling oral bacterial growth and biofilm formation on oral surfaces. Archives of Oral Biology, 58, 12, 1804-1811.
21. Filoche, S., Wong, L., Sissons, C. H. (2010). Oral Biofilms: Emerging Concepts in Microbial Ecology. J Dent Res, 89, 1, 8-18.
22. Gallardo, A., Maria, R. A., Carlos, E., Carlos, P., Julio, S. R. (2005). Chitosan-Based Microcomposites - From Biodegradable Microparticles to Self-Curing Hydrogels. CRC Press, 592.
23. Hartenbach, F. A. R. R., Silva-Boghossian, C. M., Colombo, A. P. V. (2018). The effect of supragingival biofilm re-development on the subgingival microbiota in chronic periodontitis. Archives of Oral Biology, 85, 51-57.
24. Shchipkova, A. Y., Nagaraja, H. N., Kumar, P. S. (2005). Subgingival Microbial Profiles of Smokers with Periodontitis. Journal Dental Research, 89 (11), 1247-1253.
25. Marin, M. J. et al. (2018). Validation of a multiplex qPCR actinomycetemcomitans and Porphyromonas gingivalis: In vitro and subgingival plaque samples. Archives of Oral Biology, 88, 47-53.
