Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
Cel'yu nastoyaschey stat'i yavlyaetsya ocenka predlozhennogo kompleksa lecheniya ploskoy formy leykoplakii slizistoy obolochki rta v sravnenii s tradicionnym metodom. Metodologiya provedeniya raboty zaklyuchalas' v sleduyuschem. Dve gruppy pacientov poluchali lechenie po povodu ploskoy formy leykoplakii slizistoy obolochki rta: pervaya gruppa (34 pacienta) – poluchali tradicionnoe lechenie, vtoraya (30 pacientov) – predlozhennyy kompleks lecheniya, vklyuchavshiy fotodinamicheskuyu terapiyu i korrekciyu svobodno-radikal'nyh processov rotovoy zhidkosti. Rezul'taty provedennoy sravnitel'noy ocenki klinicheskih rezul'tatov i pokazateley hemilyuminescencii rotovoy zhidkosti cherez 1,5 i 6 mesyacev byli sleduyuschimi: otmecheno dostovernoe snizhenie v obeih gruppah, no vo II gruppe pokazateli byli sopostavimy s pokazatelyami normy; klinicheskiy analiz pokazal, chto fotodinamicheskaya terapiya s gelem propolisa pozvolyaet sokratit' sroki likvidacii giperkeratoza: v I gruppe pacientov (tradicionnoe lechenie) chastichnoe klinicheskoe vyzdorovlenie k koncu sroka lecheniya otmechalos' u 11 (34,7 %) pacientov, polnogo klinicheskogo vyzdorovleniya ne bylo otmecheno ni u odnogo pacienta; vo II gruppe k koncu sroka lecheniya bylo otmecheno polnoe klinicheskoe vyzdorovlenie u vseh pacientov. Otdalennye rezul'taty parametrov hemilyuminescencii rotovoy zhidkosti posle fotodinamicheskoy terapii, v svyazi s polnoy eliminaciey ochagov leykoplakii, byli bolee stabil'nymi i sootvetstvovali znacheniyam normy. Takim obrazom, kompleksnoe lechenie ploskoy formy leykoplakii s ispol'zovaniem fotodinamicheskoy terapii i gelya propolisa vyzyvaet normalizaciyu epitelial'nogo sloya slizistoy obolochki i yavlyaetsya prostym i effektivnym metodom.
fotodinamicheskaya terapiya, leykoplakiya, svobodno-radikal'noe okislenie, hemilyuminescenciya, slizistaya obolochka rta
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