Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
from 01.01.2004 until now
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
from 01.01.1983 until now
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
Ufa, Russian Federation
Ufa, Ufa, Russian Federation
UDC 616.31
The importance of studying ameloblastic fibromas in children is underscored by the limited availability of clinical data, as the tumor is rare—representing between 1% and 4.5% of all odontogenic neoplasms in young patients. Therefore, clinical guidelines for diagnosis and treatment are often based on case series and retrospective studies. Furthermore, the specific nature of childhood limits the use of radical surgical methods due to the potential consequences for the development of the facial skeleton and the child's psychosocial adaptation. A mother and her 14-year-old child presented to a specialized clinic at a multidisciplinary hospital complaining of a left mandibular deformity. The patient's medical history revealed that the tumor was discovered incidentally during a visit to a local dentist, and they were referred to the Republican Children's Clinical Hospital in Ufa. A clinical, radiological, and computed tomography examination revealed a space-occupying lesion localized in the area of the angle and body of the left mandible. In the operating room, under endotracheal anesthesia, an organ-preserving procedure was performed: tumor enucleation and curettage of the bone walls of the tumor through an approach from the left submandibular region. The bone surface was treated with an electrocoagulator to completely remove the soft tissue remnants of the tumor, and the wound was sutured with drainage. A gross specimen was sent for histological examination. A repeat CT scan was performed: there is no evidence of tumor recurrence, the residual bone cavity is regenerating, and the bone tissue is recovering. In conclusion, the following conclusions can be drawn: given the high regenerative capacity of bone tissue in children, in our opinion, surgical treatment of benign tumors should be performed using a marginal resection, i.e., an organ-preserving approach.
ameloblastic fibroma (AF), computed tomography (CT), organ-preserving surgery, histological examination, tumor
1. Vasilyuk V.P., Shtraube G.I., Chetvertnyh V.A., Fayzrahmanov R.A., Dolgova E.V. Retrospektivnoe issledovanie defektov i deformaciy chelyustey. Ural'skiy medicinskiy zhurnal. 2019;(12):26-29. [Vasilyuk V.P., Straube G.I., Chetvertnykh V.A., Fayzrakhmanov R.A., Dolgova E.V. Retrospective research defects and deformities of jaw. Ural Medical Journal. 2019;(12):26-29. (In Russ.)]. https://doi.org/10.25694/URMJ.2019.12.08
2. Maliya H.I., Burova I.V., Litvinenko E.A., Gogua M.G., Semochkin M.N., Solov'eva E.R. i dr. Harakternye rentgenologicheskie priznaki opuholevyh i opuholepodobnyh porazheniy kostnoy tkani chelyustno-licevoy oblasti. Vestnik rentgenologii i radiologii. 2024;105(5):262-281. [Maliya Kh.I., Burova I.V., Litvinenko E.A., Gogua M.G., Semochkin M.N., Solovyeva E.R. et al. Characteristic Radiological Signs of Tumor and Tumor-Like Lesions of Maxillofacial Bone Tissue. Journal of radiology and nuclear medicine. 2024;105(5):262-281. (In Russ.)]. https://doi.org/10.20862/0042-4676-2024-105-5-262-281
3. Timofeev A.A., Ushko N.A., Gichka S.G. Morfologicheskie osobennosti ameloblastom. Sovremennaya stomatologiya. 2017;(3):58. [Tymofieiev O., Ushko N., Gichka S. Morphological features of ameloblastomas. Sovremennaâ stomatologiâ. 2017;(3):58. (In Russ.)].
4. Semkin V.A., Grigor'yan A.S., Babichenko I.I., Usachev E.S., Zareckaya A.S. Osobennosti hirurgicheskoy taktiki pri razlichnyh formah ameloblasticheskih opuholey. Stomatologiya. 2012;91(4):25-27. [Semkin V.A., Grigoryan A.S., Babichenko I.I., Usachev E.S., Zaretskaia A.S. Surgical tactics by various ameloblastic tumors. Stomatology. 2012;91(4):25-27. (In Russ.)]. https://www.mediasphera.ru/issues/stomatologiya/2012/4/030039-1735201247?sphrase_id=477156
5. Yakovlev S.V., Topol'nickiy O.Z., Lezhnev D.A., Gurgenadze A.P., Zhuravleva A.V., Makeev A.V. Pervichnaya odontogennaya opuhol' u detey. Stomatologiya. 2023;102(2):46-53. [Yakovlev S.V., Topolnitsky O.Z., Lezhnev D.A., Gurgenadze A.P., Zhuravleva A.V., Makeev A.V. Primordial odontogenic tumor in children. Stomatology. 2023;102(2):46-53. (In Russ.)]. https://doi.org/10.17116/stomat202310202146
6. Ahire M.S., Tupkari J.V., Chettiankandy T.J., Thakur A., Agrawal R.R. Odontogenic tumors: A 35-year retrospective study of 250 cases in an Indian (Maharashtra) teaching institute. Indian journal of cancer. 2018;55(3):265-272. https://doi.org/10.4103/ijc.IJC_145_18
7. Atarbashi-Moghadam S., Ghomayshi M., Sijanivandi S. Unusual microscopic changes of Ameloblastic Fibroma and Ameloblastic Fibro-odontoma: A systematic review. Journal of clinical and experimental dentistry. 2019;11(5):e476-e481. https://doi.org/10.4317/jced.55460
8. Bilodeau E.A., Collins B.M. Odontogenic Cysts and Neoplasms. Surgical pathology clinics. 2017;10(1):177-222. https://doi.org/10.1016/j.path.2016.10.006
9. Bilodeau E.A., Hunter K.D. Odontogenic and Developmental Oral Lesions in Pediatric Patients. Head and neck pathology. 2021;15(1):71-84. https://doi.org/10.1007/s12105-020-01284-3
10. Chrcanovic B.R., Brennan P.A., Rahimi S., Gomez R.S. Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review. Journal of oral pathology & medicine. 2018;47(4):315-325. https://doi.org/10.1111/jop.12622
11. Cieliszka C., Galmiche-Rolland L., Khonsari R.H. Early presentation in ameloblastic fibroma. Journal of stomatology, oral and maxillofacial surgery. 2020;121(1):95-97. https://doi.org/10.1016/j.jormas.2019.04.015
12. Leuci S., Coppola N., Mignogna M.D., Di Lauro A.E. Peripheral ameloblastic fibroma: a rare case report. European journal of paediatric dentistry. 2023;24(3):178-179. https://doi.org/10.23804/ejpd.2023.1572
13. Martín-Granizo López R., Ortega L., González Corchón M.A., Berguer Sández A. Ameloblastic fibroma of the mandible. Report of two cases. Medicina oral. 2003;8(2):150-153. English, Spanish. https://pubmed.ncbi.nlm.nih.gov/12618676
14. Mohapatra P.K., Choudhury A.R., Parkash H. Ameloblastic fibroma in the midline of mandible: a case report. The Journal of clinical pediatric dentistry. 2000;24(4):321-327. https://doi.org/10.17796/jcpd.24.4.a52j7477r4650366
15. Nasir A., Khare A., Ali I., Khan M.I. Ameloblastic fibroma: A case report. Journal of oral and maxillofacial pathology. 2023;27(Suppl 1):S60-S63. https://doi.org/10.4103/jomfp.jomfp_337_22
16. Phattarataratip E., Sappayatosok K. The Significance of Relative Claudin Expression in Odontogenic Tumors. Head and neck pathology. 2020;14(2):480-488. https://doi.org/10.1007/s12105-019-01072-8
17. Ramakrishnan D.S., Gouthaman S.S., Muthusekhar M.R. Ameloblastic fibrosarcoma transformation from ameloblastic fibroma. National journal of maxillofacial surgery. 2022;13(Suppl 1):S145-S149. https://doi.org/10.4103/njms.NJMS_100_20
