ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES

Anna Stepanova; Marina Nagaeva; Alina Sagandykova; Konstantin Polunov; Marina Semenova

doi:10.18481/2077-7566-2026-22-1-86-92

VAK Russia 3.1.7 UDC 616.31

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ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES

Published in Actual problems in dentistry · Volume 22, Issue 1 · Pages 86–92 · Rubric: SURGICAL DENTISTRY AND IMPLANTOLOGY. REVIEWS

DOI: https://doi.org/10.18481/2077-7566-2026-22-1-86-92

Received: 07.04.2026 Accepted: 19.04.2026 Published: 19.04.2026 Language of publication: RUS

Authors

Anna Stepanova

Marina Nagaeva

Alina Sagandykova

Konstantin Polunov

et al.

Marina Semenova

Anna Stepanova

Academic degree: candidate of medical sciences

Tyumen state medical University Associate Professor of the Department · Department of Therapeutic Dentistry · Russian Federation · Tyumen

Marina Nagaeva

Academic degree: candidate of medical sciences

Science rang: docent

Tyumenskiy gosudarstvennyy medicinskiy universitet zaveduyuschaya kafedroy terapevticheskoy i detskoy stomatologii · Russian Federation · Тюмень

Alina Sagandykova

Tyumen State Medical University Russian Federation · Tyumen

Konstantin Polunov

Tyumen State Medical University Russian Federation · Tyumen

Marina Semenova

Tyumen State Medical University Senior Lecturer · Department of Therapeutic Dentistry · Russian Federation · Tyumen

ABSTRACT

Periodontitis is one of the leading causes of tooth loss in adults and is often an indication for implant-supported rehabilitation. Aim – to analyze bone grafting techniques and bone graft materials used in implant placement in patients with periodontal diseases, with an assessment of their effect on osseointegration processes and the success of implant treatment. Materials and Methods. An analysis was conducted of Russian and international publications from 2016–2025 selected from the PubMed and eLibrary bibliographic databases using keyword searches. The review is based on 29 literature sources. Results and Discussion. Dental implantation in patients with periodontitis is often associated with peri-implant diseases due to deterioration of the biological conditions required for osseointegration. The bone augmentation methods used to restore bone volume before or during implantation in patients with periodontitis have their own characteristics and limitations. In periodontally compromised patients, autogenous, allogeneic, xenogeneic, and synthetic materials are used; however, autogenous bone is the most effective, although its availability is limited. The key requirements in planning bone grafting procedures are predictability of the regenerated bone volume, stability of soft-tissue closure, and minimization of infectious complications. The use of immediate implantation directly after extraction of teeth affected by periodontitis is undesirable; however, studies show that thorough debridement of the socket, the use of antiseptics, and bone grafting materials make it possible to achieve osseointegration even during immediate implantation into an infected socket. The ridge-splitting technique is used in cases of pronounced horizontal bone deficiency, and in periodontal cases, where the cortical plates are often thinned, the risk of cracks and fenestrations increases; therefore, indications for its use should be strict, and preference is often given to guided bone regeneration or block grafting. Autogenous block grafting provides high osteogenic potential and strong structural support. Achieving a favorable surgical outcome cannot be considered in isolation from the general condition of the periodontal tissues and the control of the inflammatory process.

KEYWORDS

periodontitis, implant treatment, peri-implantitis, bone grafting, osseointegration, osteoplastic materials

1. Moskovskiy A.V., Skvorcova D.A., Stepanova V.V., Hramova Ya.E. Protezirovanie pri parodontite. Problemy sovremennoy nauki i innovacii. 2025;(2):45-50. [Moskovsky A.V., Skvortsova D.A., Stepanova V.V., Khramova Ya.E. Prosthetics for Periodontitis. Problemy sovremennoi nauki i innovatsii. 2025;(2):45-50. (In Rus.)]. https://www.elibrary.ru/item.asp?id=82463188

2. Polupan P.V., Sipkin A.M. Optimizaciya hirurgicheskogo lecheniya bol'nyh, nuzhdayuschihsya v provedenii kostnoplasticheskih operaciy v polosti rta pri podgotovke k dental'noy implantacii: Uchebno-metodicheskoe posobie. Moskva: Gosudarstvennoe byudzhetnoe uchrezhdenie zdravoohraneniya Moskovskoy oblasti "Moskovskiy oblastnoy nauchno-issledovatel'skiy klinicheskiy institut im. M.F. Vladimirskogo"; 2022. 36 s. [Polupan P.V., Sipkin A.M. Optimization of Surgical Treatment of Patients in Need of Bone-Plastic Operations in the Oral Cavity in Preparation for Dental Implantation: Educational and Methodological Guide. Moscow: State Budgetary Healthcare Institution of the Moscow Region "Moscow Regional Research Clinical Institute named after M.F. Vladimirsky"; 2022. 36 p. (In Russ.)]. https://www.elibrary.ru/item.asp?id=49741783

3. Careva T.V., Balmasova I.P., Carev V.N. Poddesnevoy mikrobiom pri zabolevaniyah parodonta i komorbidnoy patologii (metaanaliz). Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2024;101(2):281-292. [Tsareva T.V., Balmasova I.P., Tsarev V.N. Subgingival microbiome in periodontal disease and comorbid pathology (meta-analysis). Journal of microbiology, epidemiology and immunobiology. 2024;101(2):281-292]. https://doi.org/10.36233/0372-9311-500

4. Atieh M.A., Alsabeeha N.H., Payne A.G., Ali S., Faggion C.M.J., Esposito M. Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development. The Cochrane database of systematic reviews. 2021;4(4):CD010176. https://doi.org/10.1002/14651858.CD010176.pub3

5. Atieh M.A., Shah M., Hakam A., Aid A., Tawse-Smith A., Alsabeeha N.H.M. Peri-Implantitis and Survival Outcomes of Tissue Level Versus Bone Level Dental Implants: A Systematic Review and Meta-Analysis. Clinical and experimental dental research. 2025;11(5):e70242. https://doi.org/10.1002/cre2.70242

6. Berglundh T., Armitage G., Araujo M.G., Avila-Ortiz G., Blanco J., Camargo P.M. et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. Journal of clinical periodontology. 2018;45(Suppl 20):S286–S291. https://doi.org/10.1111/jcpe.12957

7. Buser D., Urban I., Monje A., Kunrath M.F., Dahlin C. Guided bone regeneration in implant dentistry: Basic principle, progress over 35 years, and recent research activities. Periodontology 2000. 2023;93(1):9-25. https://doi.org/10.1111/prd.12539

8. Cao Y., Ni Q., Bao C., Cai C., Wang T., Ruan X. et al. The Role of Pericyte Migration and Osteogenesis in Periodontitis. Journal of dental research. 2024;103(7):723-733. https://doi.org/10.1177/00220345241244687

9. Castro F., Bouzidi A.S., Fernandes J.C.H., Bottino M.C., Fernandes G.V.O. Bone tissue regeneration in peri-implantitis: A systematic review of randomized clinical trials. The Saudi dental journal. 2023;35(6):589-601. https://doi.org/10.1016/j.sdentj.2023.05.022

10. Chahal G., Yadav B.K., Thakur R.K., Saini R., Kumar M., Saurabh K. Clinicoradiographic Evaluation of Long-term Efficacy and Risk Factors Associated with Dental Implants used for Full Mouth Rehabilitation. Journal of pharmacy & bioallied sciences. 2022;14(Suppl 1):S1014–S1018. https://doi.org/10.4103/jpbs.jpbs_788_21

11. Chiapasco M., Casentini P. Horizontal bone-augmentation procedures in implant dentistry: prosthetically guided regeneration. Periodontology 2000. 2018;77(1):213-240. https://doi.org/10.1111/prd.12219

12. Ciszyński M., Dominiak S., Dominiak M., Gedrange T., Hadzik J. Allogenic Bone Graft in Dentistry: A Review of Current Trends and Developments. International journal of molecular sciences. 2023;24(23):16598. https://doi.org/10.3390/ijms242316598

13. Cosyn J., Struys T., Van Hove P.J., De Buyser S., De Bruyckere T. A Randomized Controlled Trial on the Timing of Soft-Tissue Augmentation in Immediate Implant Placement: Hard-Tissue Changes and Clinical Outcome. Journal of clinical periodontology. 2024;51(11):1534-1544. https://doi.org/10.1111/jcpe.14060

14. Ferreira S.D., Martins C.C., Amaral S.A., Vieira T.R., Albuquerque B.N., Cota L.O.M. et al. Periodontitis as a risk factor for peri-implantitis: Systematic review and meta-analysis of observational studies. Journal of dentistry. 2018;79:1-10. https://doi.org/10.1016/j.jdent.2018.09.010

15. Garcia D.C., Mingrone L.E., de Sá M.J.C. Evaluation of Osseointegration and Bone Healing Using Pure-Phase β - TCP Ceramic Implant in Bone Critical Defects. A Systematic Review. Frontiers in veterinary science. 2022;9:859920. https://doi.org/10.3389/fvets.2022.859920

16. Jo S.H., Kim Y.K., Choi Y.H. Histological Evaluation of the Healing Process of Various Bone Graft Materials after Engraftment into the Human Body. Materials (Basel). 2018;11(5):714. https://doi.org/10.3390/ma11050714

17. Kotsakis G.A., Ganesan S.M. Microbial Dysbiosis, Titanium Release, and Peri-implantitis. Journal of dental research. 2025;104(5):473-480. https://doi.org/10.1177/00220345241307939

18. Li J.T.W., Leung Y.Y. Effect of Antiresorptive Drugs on Osseointegrated Dental Implants: A Systematic Review. Journal of clinical medicine. 2024;13(7):2091. https://doi.org/10.3390/jcm13072091

19. Monje A., Insua A., Wang H.L. Understanding Peri-Implantitis as a Plaque-Associated and Site-Specific Entity: On the Local Predisposing Factors. Journal of clinical medicine. 2019;8(2):279. https://doi.org/10.3390/jcm8020279

20. Oliveira J.A., de Oliveira Alves R., Nascimento I.M., Hidalgo M.A.R., Scarel-Caminaga R.M., Cristina Pigossi S. Pro- and anti-inflammatory cytokines and osteoclastogenesis-related factors in peri-implant diseases: systematic review and meta-analysis. BMC Oral Health. 2023;23(1):420. https://doi.org/10.1186/s12903-023-03072-1

21. Rathore P., Manjunath S., Singh R. Evaluating and comparing the efficacy of the microsurgical approach and the conventional approach for the periodontal flap surgical procedure: A randomized controlled trial. Dental and medical problems. 2024;61(1):23-28. https://doi.org/10.17219/dmp/147183

22. Roccuzzo M., Mirra D., Roccuzzo A. Surgical treatment of peri-implantitis. British dental journal. 2024;236(10):803-808. https://doi.org/10.1038/s41415-024-7405-9

23. Ryoo K.S., Kim K.H., Cho Y.D., Seol Y.J., Ku Y. Effects of adjacent periodontitis on osseointegrated dental implants. Journal of periodontal & implant science. 2024;54(4):280-291. https://doi.org/10.5051/jpis.2302400120

24. Sekar P., Rizvi Z., Abdullah N., Samsudin A.R., Kheder W. Oral microbiota interactions with titanium implants: A pilot in-vivo and in-vitro study on the impact of peri-implantitis. PLoS One. 2025;20(7):e0321428. https://doi.org/10.1371/journal.pone.0321428

25. Smeets R., Matthies L., Windisch P., Gosau M., Jung R., Brodala N. et al. Horizontal augmentation techniques in the mandible: a systematic review. International journal of implant dentistry. 2022;8(1):23. https://doi.org/10.1186/s40729-022-00421-7

26. Valles C., Vilarrasa J., Barallat L., Pascual A., Nart J. Efficacy of soft tissue augmentation procedures on tissue thickening around dental implants: A systematic review and meta-analysis. Clinical oral implants research. 2022;33(Suppl 23):72-99. https://doi.org/10.1111/clr.13920

27. Wang K., Zhang J., Ding M., Xie Y., Wang Y., Jin C. et al. Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis. International journal of implant dentistry. 2025;11(1):45. https://doi.org/10.1186/s40729-025-00630-w

28. Yazan M., Kocyigit I.D., Atil F., Tekin U., Gonen Z.B., Onder M.E. Effect of hyaluronic acid on the osseointegration of dental implants. The British journal of oral & maxillofacial surgery. 2019;57(1):53-57. https://doi.org/10.1016/j.bjoms.2018.08.014

29. Zhang Q., Guo S., Li Y., Li Z., Wang D., Zhang K. Analysis of risk indicators for implant failure in patients with chronic periodontitis. BMC Oral Health. 2024;24(1):1051. https://doi.org/10.1186/s12903-024-04806-5

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GOST

Stepanova A. I., Nagaeva M. O., Sagandykova A. A., Polunov K. D., Semenova M. V. ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES // Actual problems in dentistry. 2026. no. 1. pp. 86-92. DOI: https://doi.org/10.18481/2077-7566-2026-22-1-86-92. (Date of access 25.10.2026).

MLA

Anna Stepanova, Nagaeva M. O., Sagandykova A. A., Polunov K. D., Semenova M. V.. "ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES." Actual problems in dentistry 22.1 (2026): 86-92. DOI: https://doi.org/10.18481/2077-7566-2026-22-1-86-92.

APA

Stepanova A. I., Nagaeva M. O., Sagandykova A. A., Polunov K. D., Semenova M. V. (2026). ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES. Actual problems in dentistry, 22(1), 86-92. https://doi.org/10.18481/2077-7566-2026-22-1-86-92

Chicago

Anna Stepanova, Nagaeva M. O., Sagandykova A. A., Polunov K. D., Semenova M. V.. "ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES." Actual problems in dentistry 22, no. 1 (2026): 86-92. https://doi.org/10.18481/2077-7566-2026-22-1-86-92.

WIKI

{{cite journal | author = Stepanova A. I., Nagaeva M. O., Sagandykova A. A., Polunov K. D., Semenova M. V. | title = ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES | journal = Actual problems in dentistry | year = 2026 | volume = 22 | issue = 1 | pages = 86-92 | doi = 10.18481/2077-7566-2026-22-1-86-92 }}

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ANALYSIS OF BONE GRAFTING TECHNIQUES AND OSTEOPLASTIC MATERIALS USED IN IMPLANT PLACEMENT IN PATIENTS WITH PERIODONTAL DISEASES

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