MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON

Tat'yana Elovicova; Elena Ermishina; Svetlana Sablina; Yuliya Mandra; Sergey Griroriev; V. Karaseva; N. Gegalina; Natal'ya Uporova; Nadezhda Gabdulvalieva; Varvara Pryadeina

doi:10.18481/2077-7566-2026-22-1-30-37

VAK Russia 3.1.7 UDC 616.31

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MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON

Published in Actual problems in dentistry · Volume 22, Issue 1 · Pages 30–37 · Rubric: TERAPEUTIC DENTISTRY. ORIGINAL RESEARCH PAPERS

DOI: https://doi.org/10.18481/2077-7566-2026-22-1-30-37

Received: 04.04.2026 Accepted: 19.04.2026 Published: 19.04.2026 Language of publication: RUS

Authors

Tat'yana Elovicova

Elena Ermishina

Svetlana Sablina

ORCID

Yuliya Mandra

ORCID

et al.

Sergey Griroriev

V. Karaseva

N. Gegalina

Natal'ya Uporova

Nadezhda Gabdulvalieva

Varvara Pryadeina

Tat'yana Elovicova

Academic degree: doctor of medical sciences

Ural State Medical University Professor of the Department · Department of Therapeutic Dentistry and Propedeutics of Dental Diseases · Ekaterinburg

Elena Ermishina

Ural State Medical University Docent of Department · Department of General Chemistry · Russian Federation · Ekaterinburg

Svetlana Sablina

Ural State Medical University assistant of the department · Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases · Ekaterinburg

ORCID

Yuliya Mandra

Academic degree: doctor of medical sciences

Science rang: professor

Ural State Medical University Director of the Institute of Dentistry, Professor of Department · Department of therapeutic dentistry and propaedeutics of dental diseases · Russian Federation · Yekaterinburg

ORCID

Sergey Griroriev

Academic degree: doctor of medical sciences

Science rang: professor

Ural State Medical University Head of the Department · Department of Therapeutic Dentistry and Propedeutics of Dental Diseases · Ekaterinburg

V. Karaseva

Academic degree: candidate of medical sciences

Ural State Medical University Docent of Department · Department of Orthopedic Dentistry and General Dentistry · Russian Federation · Ekaterinburg

N. Gegalina

Academic degree: candidate of medical sciences

Ural State Medical University Docent of Department · Department of Therapeutic Dentistry and Propedeutics of Dental Diseases · Ekaterinburg

Natal'ya Uporova

Academic degree: candidate of medical sciences

Science rang: docent

Ural State Medical University Associate Professor · Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases · Ekaterinburg

Nadezhda Gabdulvalieva

Ural State Medical University Assistant of the Department · Department of Therapeutic Dentistry and Propedeutics of Dental Diseases · Russian Federation · Ekaterinburg

Varvara Pryadeina

Ural State Medical University Russian Federation · Ekaterinburg

ABSTRACT

Subject. The subject of this study is the toothpaste with herbal extracts and polydon. Objective. The study aims to find out the toothpastes that are most commonly used by senior students of the Dental Institute, as well as to investigate the effect of SPLAT Professional Healthy Gums Toothpaste with herbal extracts and polydon on mineralizing parameters of oral fluid. Methodology. The study is conducted by the Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases, the Department of General Chemistry at Ural State Medical University. To achieve the outlined objective, to investigate the effect of SPLAT Professional Healthy Gums Toothpaste with herbal extracts and polydon on mineralizing parameters of oral fluid, the study group comprised 46 volunteers among students in the first, third and fourth years of the Dental Institute (16 males, 30 females) aged 18 to 24. The physicochemical properties of SPLAT Professional Healthy Gums Toothpaste were assessed using concentrations (1 %, 2 % and 3 %) of toothpaste solutions in water. Statistical analysis of results was performed using MS Excel software package together with a set of tools for medical statistics. The statistical significance was assessed using Student’s t-distribution. The results were considered significantly different at p ≤0.05 [2–6]. Conclusions. The elevated levels of phosphorus and calcium found in toothpaste water extracts increase levels of these two elements in the oral fluid of volunteer patients. Initially, an increase in phosphorus content in the toothpaste compared to the calcium content proportionally enhanced the phosphorus content in patients’ oral fluid. A temporary decrease in total Ca/P ratio in study participants’ oral fluid was observed, while the oral fluid was still oversaturated with necessary inorganic elements creating an environment that maintains the consistent structure of tooth tissues, that is mineralization (and remineralization).

KEYWORDS

oral fluid, toothpaste with herbal extracts and polydon, therapeutic effect, study of mineralization potential of saliva, sialometry

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Sergey Zholudev

zholudev_se@mail.ru

Deputy editor

Yuliya Mandra

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GOST

Elovicova T. M., Ermishina E. Y., Sablina S. N., Mandra Y. V., Griroriev S. S., Karaseva V. V., Gegalina N. M., Uporova N. A., Gabdulvalieva N. A., Pryadeina V. V. MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON // Actual problems in dentistry. 2026. no. 1. pp. 30-37. DOI: https://doi.org/10.18481/2077-7566-2026-22-1-30-37. (Date of access 13.10.2026).

MLA

Tat'yana Elovicova, Ermishina E. Y., Sablina S. N., Mandra Y. V., Griroriev S. S., Karaseva V. V., Gegalina N. M., Uporova N. A., Gabdulvalieva N. A., Pryadeina V. V.. "MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON." Actual problems in dentistry 22.1 (2026): 30-37. DOI: https://doi.org/10.18481/2077-7566-2026-22-1-30-37.

APA

Elovicova T. M., Ermishina E. Y., Sablina S. N., Mandra Y. V., Griroriev S. S., Karaseva V. V., Gegalina N. M., Uporova N. A., Gabdulvalieva N. A., Pryadeina V. V. (2026). MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON. Actual problems in dentistry, 22(1), 30-37. https://doi.org/10.18481/2077-7566-2026-22-1-30-37

Chicago

Tat'yana Elovicova, Ermishina E. Y., Sablina S. N., Mandra Y. V., Griroriev S. S., Karaseva V. V., Gegalina N. M., Uporova N. A., Gabdulvalieva N. A., Pryadeina V. V.. "MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON." Actual problems in dentistry 22, no. 1 (2026): 30-37. https://doi.org/10.18481/2077-7566-2026-22-1-30-37.

WIKI

{{cite journal | author = Elovicova T. M., Ermishina E. Y., Sablina S. N., Mandra Y. V., Griroriev S. S., Karaseva V. V., Gegalina N. M., Uporova N. A., Gabdulvalieva N. A., Pryadeina V. V. | title = MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON | journal = Actual problems in dentistry | year = 2026 | volume = 22 | issue = 1 | pages = 30-37 | doi = 10.18481/2077-7566-2026-22-1-30-37 }}

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MECHANISMS OF MINERALIZATION ACTION FOR THERAPEUTIC PREVENTIVE TOOTHPASTE WITH HERBAL EXTRACTS AND POLYDON

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