DIAGNOSIS OF ORAL LICHEN PLANUS

Anna Dregalkina; Natali Borisenko; Dmitriy Tolstykh; Anna Yepishova; Nina Chernyshova; Aleksandr Plotnikov

doi:10.18481/2077-7566-2025-21-4-58-64

VAK Russia 3.1.7 UDC 616.31

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DIAGNOSIS OF ORAL LICHEN PLANUS

Published in Actual problems in dentistry · Volume 21, Issue 4 · Pages 58–64 · Rubric: THERAPEUTIC DENTISTRY

DOI: https://doi.org/10.18481/2077-7566-2025-21-4-58-64

Received: 14.01.2026 Accepted: 29.01.2026 Published: 29.01.2026 Language of publication: RUS

Authors

Anna Dregalkina

Natali Borisenko

ORCID SPIN

Dmitriy Tolstykh

Anna Yepishova

et al.

Nina Chernyshova

Aleksandr Plotnikov

Anna Dregalkina

Academic degree: candidate of medical sciences

Ural State Medical University associate professor · Department of Surgical Dentistry, Otolaryngology and CHLH · Ekaterinburg

Natali Borisenko

Ural State Medical University Russian Federation · Ekaterinburg

ORCID SPIN

Dmitriy Tolstykh

Ural State Medical University Assistant of the Department · Department of Pathological Anatomy and Forensic Medicine · Russian Federation · Ekaterinburg

Anna Yepishova

Academic degree: candidate of medical sciences

Ural State Medical University docent of the department · Department of Therapeutic Dentistry and Dental Diseases · Ekaterinburg

Nina Chernyshova

Academic degree: candidate of medical sciences

Science rang: docent

Ural State Medical University Docent · Department of Therapeutic Dentistry · Ekaterinburg

Aleksandr Plotnikov

Ural State Medical University Assistant of the department · Department of Pediatric Dentistry and Orthodontics · Russian Federation · Yekaterinburg

ABSTRACT

The subject of the research is a study of the diagnostic features of oral lichen planus and the application of diagnostic criteria. The aim of the research is to determine the role of pathomorphological diagnostics of oral lichen planus in making a diagnosis. Methodology. The study was conducted at the Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases, the Department of Surgical Dentistry, Otolaryngology, and Maxillofacial Surgery, as well as at the clinical site of the Department of Pathological Anatomy and Forensic Medicine in the histology laboratory of the General Pathology Department of the Central Research Laboratory of the Ural State Medical University (Yekaterinburg). The study was based on an analysis of clinical examination data from 32 patients and a study of histological specimens from biopsy specimens. Results. Surgical biopsy of patients with suspected oral lichen planus revealed discrepancies between clinical and histological diagnoses. As the clinical presentation of oral lichen planus often overlaps with other diseases, and applying the new American Academy of Oral and Maxillofacial Pathology criteria showed that not all specimens contained all required pathological features, the reliability of these criteria in practice remains uncertain. Conclusion. A comprehensive approach combining clinical and histopathological analysis is crucial for diagnosing and managing lichen planus. This is mandatory not only for initial diagnosis but also for patient monitoring, particularly in cases of suspected malignancy.

KEYWORDS

oral lichen planus, lichen planus, oral mucosa, pathomorphology, diagnostics

1. Gururaj N., Hasinidevi P., Janani V., Divynadaniel T. Diagnosis and management of oral lichen planus - Review. Journal of oral and maxillofacial pathology. 2021;25(3):383-393. https://doi.org/10.4103/jomfp.jomfp_386_21

2. Grigor'ev S.S., Ron' G.I., Epishova A.A. Giperkeratozy slizistoy obolochki rta (krasnyy ploskiy lishay, leykoplakiya). Ekaterinburg: Tirazh; 2019. 37 s. [Grigoriev S.S., Ron' G.I., Epishova A.A. Hyperkeratoses of the Oral Mucosa (Lichen Planus, Leukoplakia). Ekaterinburg: Tirazh; 2019. 37 p. (In Russ.)]. https://doi.org/10.18481/textbook_5d8c980a88a414.80041985

3. Erthal A., Lourenço S.V., Nico M.M.S. Oral lichen planus: case series and experience in a tertiary dermatology service in Brazil. Anais brasileiros de dermatologia. 2023;98(4):493-497. https://doi.org/10.1016/j.abd.2022.06.005

4. Rabinovich O.F., Rabinovich I.M., Babichenko I.I. Krasnyy ploskiy lishay slizistoy obolochki rta – klinika, diagnostika i lechenie. Moskva: Rossiyskaya akademiya nauk; 2018. 80 s. [Rabinovich O.F., Rabinovich I.M., Babichenko I.I. Oral Lichen Planus: Clinical Features, Diagnosis, and Treatment. Moscow: Russian Academy of Sciences; 2018. 80 p. (In Russ.)]. https://new.ras.ru/work/publishing/monographs/krasnyy-ploskiy-lishay-slizistoy-obolochki-rta-klinika-diagnostika-i-lechenie/

5. Li C., Tang X., Zheng X., Ge S., Wen H., Lin X. et al. Global Prevalence and Incidence Estimates of Oral Lichen Planus: A Systematic Review and Meta-analysis. JAMA dermatology. 2020;156(2):172-181. https://doi.org/10.1001/jamadermatol.2019.3797

6. Grabovskaya O.V., Kayumova L.N., Nikulina A.S., Damdinova B.Sh., Shahmanova S.I. Problema diagnostiki krasnogo ploskogo lishaya pri porazhenii slizistoy obolochki polosti rta. Rossiyskiy zhurnal kozhnyh i venericheskih bolezney. 2022;25(3):229–238. [Grabovskaya O.V., Kayumova L.N., Nikulina A.S., Damdinova B.S., Shakhmanova S.I. Problems of diagnostics of oral lichen planus. Russian Journal of Skin and Venereal Diseases. 2022;25(3):229–238. (In Russ.)]. https://doi.org/10.17816/dv109678

7. Hansen B.T., Payne J.B., Samson K.K., Giannini P.J. Assessing the Agreement of Light Microscopic Evaluation of Oral Lichen Planus Lesions With Associated Direct Immunofluorescence Evaluation. Clinical pathology. 2023;16:2632010X231197111. https://doi.org/10.1177/2632010X231197111

8. Gruda Y., Albrecht M., Buckova M., Haim D., Lauer G., Koch E. et al. Characteristics of Clinically Classified Oral Lichen Planus in Optical Coherence Tomography: A Descriptive Case-Series Study. Diagnostics (Basel). 2023;13(16):2642. https://doi.org/doihttps://doi.org/10.3390/diagnostics13162642

9. Mathur M., Jha A., Thakur N., Das G., Shah S., Jaiswal S. et al. Clinicopathological Correlation in Patients with Oral Lichen Planus. Journal of Dental Pathology and Medicine. 2023;7(3):154. https://www.omicsonline.org/open-access/clinicopathological-correlation-in-patients-with-oral-lichen-planus-125322.html#citation-btn

10. Akmalova G.M., Chuykin S.V., Chernysheva N.D., Bikmurzin V.P. Sovremennye aspekty patogeneza krasnogo ploskogo lishaya slizistoy obolochki rta. Problemy stomatologii. 2021;17(1):44-50. [Akmalova G.M. Chuikin S.V., Chernysheva N.D. Bikmurzin V.P. Modern aspects of the pathogenesis of lichen planus of the oral mucosa. Actual problems in dentistry. 2021;17(1):44-50. (In Russ.)]. https://doi.org/10.18481/2077-7566-20-17-1-44-50

11. Rotaru D.I., Sofineti D., Bolboacă S.D., Bulboacă A.E. Diagnostic Criteria of Oral Lichen Planus: A Narrative Review. Acta clinica Croatica. 2020;59(3):513-522. https://doi.org/10.20471/acc.2020.59.03.16

12. Cheng Y.S., Gould A., Kurago Z., Fantasia J., Muller S. Diagnosis of oral lichen planus: a position paper of the American Academy of Oral and Maxillofacial Pathology. Oral surgery, oral medicine, oral pathology and oral radiology. 2016;122(3):332-354. https://doi.org/10.1016/j.oooo.2016.05.004

13. Mutafchieva M.Z., Tashkova D.A. Discrepancy in the Histological Diagnoses of Oral Lichen Planus Based on WHO Criteria Versus the Newly Proposed Diagnostic Set of the American Academy of Oral and Maxillofacial Pathology. Diagnostics (Basel, Switzerland). 2025;15(5):558. https://doi.org/10.3390/diagnostics15050558

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GOST

Dregalkina A. A., Borisenko N. S., Tolstykh D. V., Yepishova A. A., Chernyshova N. D., Plotnikov A. S. DIAGNOSIS OF ORAL LICHEN PLANUS // Actual problems in dentistry. 2026. no. 4. pp. 58-64. DOI: https://doi.org/10.18481/2077-7566-2025-21-4-58-64. (Date of access 05.10.2026).

MLA

Anna Dregalkina, Borisenko N. S., Tolstykh D. V., Yepishova A. A., Chernyshova N. D., Plotnikov A. S.. "DIAGNOSIS OF ORAL LICHEN PLANUS." Actual problems in dentistry 21.4 (2026): 58-64. DOI: https://doi.org/10.18481/2077-7566-2025-21-4-58-64.

APA

Dregalkina A. A., Borisenko N. S., Tolstykh D. V., Yepishova A. A., Chernyshova N. D., Plotnikov A. S. (2026). DIAGNOSIS OF ORAL LICHEN PLANUS. Actual problems in dentistry, 21(4), 58-64. https://doi.org/10.18481/2077-7566-2025-21-4-58-64

Chicago

Anna Dregalkina, Borisenko N. S., Tolstykh D. V., Yepishova A. A., Chernyshova N. D., Plotnikov A. S.. "DIAGNOSIS OF ORAL LICHEN PLANUS." Actual problems in dentistry 21, no. 4 (2026): 58-64. https://doi.org/10.18481/2077-7566-2025-21-4-58-64.

WIKI

{{cite journal | author = Dregalkina A. A., Borisenko N. S., Tolstykh D. V., Yepishova A. A., Chernyshova N. D., Plotnikov A. S. | title = DIAGNOSIS OF ORAL LICHEN PLANUS | journal = Actual problems in dentistry | year = 2026 | volume = 21 | issue = 4 | pages = 58-64 | doi = 10.18481/2077-7566-2025-21-4-58-64 }}

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