MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS

Roman Harchenko; Natalia Lazarikhina; Denis Nikolenko; Oksana Avdeenko; Maksim Putincev

doi:10.18481/2077-7566-2025-21-3-93-98

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MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS

Published in Actual problems in dentistry · Pages 93–98 · Rubric: THERAPEUTIC DENTISTRY

DOI: https://doi.org/10.18481/2077-7566-2025-21-3-93-98

Received: 03.09.2025 Accepted: 13.10.2025 Published: 29.10.2025 Language of publication: RUS

Authors

Roman Harchenko

Natalia Lazarikhina

Denis Nikolenko

ORCID

Oksana Avdeenko

ORCID

Maksim Putincev

ORCID

Roman Harchenko

I.M. Sechenov First Moscow State Medical University (Sechenov University) teacher of the department · Department of Orthopedic Dentistry · Russian Federation · Moscow

Natalia Lazarikhina

Academic degree: candidate of medical sciences

Federal State Budgetary Educational Institution of Higher Education "Russian University of Medicine" of the Ministry of Healthcare of the Russian Federation Assistant Professor of the Department · Department of Surgical Dentistry · Russian Federation · Moscow

Denis Nikolenko

I.M. Sechenov First Moscow State Medical University Associate Professor · Ortopedic dentistry

ORCID

Oksana Avdeenko

I.M. Sechenov First Moscow State Medical University Assistant Professor · therapeutic dentistry

ORCID

Maksim Putincev

Sechenov University Postgraduate student · Orthopedic dentistry · Moscow

ORCID

ABSTRACT

In modern orthopedic dentistry practice, there is an increase in the number of patients with various inflammatory diseases of the oral cavity, among them lichen planus (LP) is increasingly being detected. Statistics indicate the prevalence of LP at 1.3-2.4% among all skin diseases, while oral lichen planus (OLP) can occur in 35% of cases. Current methods of treating partial and complete edentia in these patients include many types of prosthetics, both removable and non-removable. Although OLP is not an absolute contraindication to implantation surgery, removable dentures are most often indicated for such patients. The most popular and cost-effective materials for their manufacture at the moment are acrylic plastics, thermoplastics, polyurethane. The aim of the study was to analyze the microbiological profile of the oral cavity in patients with OLP using different types of removable dentures and to identify the relationship between denture material and the level of microbial colonization. The study included 20 patients with various forms of OLP who were using acrylic, thermoplastic (nylon), and polyurethane dentures. Microbiological analysis revealed that acrylic dentures had the highest tendency for microbial colonization, including Candida species, whereas thermoplastic and polyurethane dentures demonstrated better biocompatibility. Chi-square analysis indicated a tendency toward correlation between denture material and the degree of microbial colonization, although statistical significance was not reached. The results highlight the importance of considering microbial load when selecting denture materials for OLP patients and underscore the necessity of regular microbiological monitoring.

KEYWORDS

oral lichen planus, microbial colonization, removable dentures, acrylic dentures, thermoplastic polymers, polyurethane dentures, Candida albicans

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GOST

Harchenko R. E., Lazarikhina N. M., Nikolenko D. A., Avdeenko O. Y., Putincev M. Y. MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS // Actual problems in dentistry. 2025. no. 3. pp. 93-98. DOI: https://doi.org/10.18481/2077-7566-2025-21-3-93-98. (Date of access 06.09.2026).

MLA

Roman Harchenko, Lazarikhina N. M., Nikolenko D. A., Avdeenko O. Y., Putincev M. Y.. "MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS." Actual problems in dentistry 21.3 (2025): 93-98. DOI: https://doi.org/10.18481/2077-7566-2025-21-3-93-98.

APA

Harchenko R. E., Lazarikhina N. M., Nikolenko D. A., Avdeenko O. Y., Putincev M. Y. (2025). MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS. Actual problems in dentistry, 21(3), 93-98. https://doi.org/10.18481/2077-7566-2025-21-3-93-98

Chicago

Roman Harchenko, Lazarikhina N. M., Nikolenko D. A., Avdeenko O. Y., Putincev M. Y.. "MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS." Actual problems in dentistry 21, no. 3 (2025): 93-98. https://doi.org/10.18481/2077-7566-2025-21-3-93-98.

WIKI

{{cite journal | author = Harchenko R. E., Lazarikhina N. M., Nikolenko D. A., Avdeenko O. Y., Putincev M. Y. | title = MICROBIOLOGICAL PROFILE OF THE ORAL CAVITY IN PATIENTS WITH LICHEN PLANUS: FEATURES IN REMOVABLE PROSTHETICS | journal = Actual problems in dentistry | year = 2025 | volume = 21 | issue = 3 | pages = 93-98 | doi = 10.18481/2077-7566-2025-21-3-93-98 }}

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