ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT

Mohamed M. Al; Irina Usmanova; Amina Ishmukhametova; Irina Lakman; Regina Safiullina; Liana Muzaeva

doi:10.18481/2077-7566-2022-18-2-44-54

VAK Russia 3.1 UDC 616 CSCSTI 76.29 Russian Classification of Professions by Education 31.05.03 Russian Library and Bibliographic Classification 566

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ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT

Published in Actual problems in dentistry · Volume 18, Issue 2 · Pages 44–54 · Rubric: THERAPEUTIC DENTISTRY

DOI: https://doi.org/10.18481/2077-7566-2022-18-2-44-54

Received: 08.08.2022 Accepted: 18.08.2022 Published: 18.08.2022 Language of publication: RUS

Authors

Mohamed M. Al

Irina Usmanova

Amina Ishmukhametova

Irina Lakman

et al.

Regina Safiullina

Liana Muzaeva

Mohamed M. Al

Bashkirskiy gosudarstvennyy medicinskiy universitet Department of Therapeutic Dentistry with the course of Institute of additional professional education · Russian Federation · Уфа

Irina Usmanova

Academic degree: doctor of medical sciences

Science rang: docent

Bashkirian State Medical University Professor of the Department · Department of Therapeutic Dentistry with the course of ICPE · Ufa

Amina Ishmukhametova

Academic degree: candidate of medical sciences

Bashkirian State Medical University Docent of Department · Department of Internal diseases · Ufa

Irina Lakman

Academic degree: candidate of technical sciences

Bashkir State Medical University Heaf of the scientific laboratory · scientific laboratory for the study of socio-economic problems of the regions · Russian Federation · Ufa

Bashkir State University Head of the Scientific Laboratory · Scientific Laboratory for the Study of Social and Economic Problems · Russian Federation · Ufa

Regina Safiullina

Dental polyclinic No. 2, Ufa Dentist-therapist · Russian Federation · Ufa

Liana Muzaeva

Clinics of FSBEI HE "Bashkir State Medical University" Gastroenterologist · Russian Federation · Ufa

ABSTRACT

Relevance. The authors found that the development of mucosal pathology is influenced by classical (major) and mediated hypersecretory diseases of the gastrointestinal tract. Kyoto Consensus (2014) suggested that gastroenterological patients have manifestations of functional dyspepsia, the mucosa of the stomach and duodenum has increased sensitivity to excessive production of hydrochloric acid, and various pathological changes are observed on the mucosa of the oral cavity proper. The aim was study of the relationship between the severity of dyspeptic disorders on the 7×7 questionnaire and clinical features of oral mucosal pathology manifestations in patients with classical and mediated hypersecretory diseases of the gastrointestinal tract. Materials and Methods. The study included 105 patients with the presence of classical gastrointestinal disease (simple non-atrophic chronic gastritis with dyspepsia syndrome after eradication of H.pylori) and hypersecretory mediated gastrointestinal disease (chronic pancreatitis) with increased or normal production of hydrochloric acid in the stomach. Clinical condition of oral mucosa corresponded to the presence of manifestations of classical and mediated hypersecretory diseases of the gastrointestinal tract. To assess pain intensity we used pain index index (PIH) according to Hossley-Bergman scale, examination of symptoms of functional dyspepsia (FD) and irritable bowel syndrome (IBS) was carried out by means of questionnaire "7×7". To determine statistical differences we used chi-square test, including Yates-adjusted test and Mann-Whitney test. Results. In the clinical group with classic hypersecretory gastrointestinal disease only in 25,71% of cases pathology of oral mucosa was revealed. On the background of clinical manifestations in mediated GIT pathology of oral mucosa – oral candidiasis, cheilitis, glossitis, burning sensation of the oral cavity was revealed in 100% of cases. Dyspeptic disorders according to 7×7 questionnaire prevailed in persons with indirect hypersecretory gastrointestinal disease in the form of chronic pancreatitis with GERD symptoms.

KEYWORDS

pain, burning, oral mucosa, candidiasis, aphthae, glossitis, classical and mediated hypersecretory gastrointestinal diseases, functional dyspepsia, "7×7" gastrointestinal functional dyspepsia questionnaire

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Al Mohamed M. A., Usmanova I. N., Ishmukhametova A. N., Lakman I. A., Safiullina R. A., Muzaeva L. I. ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT // Actual problems in dentistry. 2022. no. 2. pp. 44-54. DOI: https://doi.org/10.18481/2077-7566-2022-18-2-44-54. (Date of access 27.10.2026).

MLA

Mohamed M. Al, Usmanova I. N., Ishmukhametova A. N., Lakman I. A., Safiullina R. A., Muzaeva L. I.. "ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT." Actual problems in dentistry 18.2 (2022): 44-54. DOI: https://doi.org/10.18481/2077-7566-2022-18-2-44-54.

APA

Al Mohamed M. A., Usmanova I. N., Ishmukhametova A. N., Lakman I. A., Safiullina R. A., Muzaeva L. I. (2022). ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT. Actual problems in dentistry, 18(2), 44-54. https://doi.org/10.18481/2077-7566-2022-18-2-44-54

Chicago

Mohamed M. Al, Usmanova I. N., Ishmukhametova A. N., Lakman I. A., Safiullina R. A., Muzaeva L. I.. "ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT." Actual problems in dentistry 18, no. 2 (2022): 44-54. https://doi.org/10.18481/2077-7566-2022-18-2-44-54.

WIKI

{{cite journal | author = Al Mohamed M. A., Usmanova I. N., Ishmukhametova A. N., Lakman I. A., Safiullina R. A., Muzaeva L. I. | title = ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT | journal = Actual problems in dentistry | year = 2022 | volume = 18 | issue = 2 | pages = 44-54 | doi = 10.18481/2077-7566-2022-18-2-44-54 }}

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ANALYSIS OF FUNCTIONAL AND CLINICAL SYMPTOMS IN PATIENTS WITH CLASSICAL AND MEDIATED HYPERSECRETORY DISEASES OF THE GASTROINTESTINAL TRACT

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