ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS

Oksana Shulyatnikova; Anatoliy Godovalov; Gennadiy Rogozhnikov; Mihail Yakovlev; Kirill Batog; Elena Leushina

doi:10.18481/2077-7566-20-17-1-172-176

VAK Russia 14.01.2014 UDC 61 CSCSTI 76.03 Russian Classification of Professions by Education 31.02.06 Russian Library and Bibliographic Classification 566 BISAC HEA040000 CSCSTI 76.29

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ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS

Published in Actual problems in dentistry · Volume 17, Issue 1 · Pages 172–176 · Rubric: ORTHOPEDIC DENTISTRY

DOI: https://doi.org/10.18481/2077-7566-20-17-1-172-176

Received: 22.02.2021 Accepted: 03.03.2021 Language of publication: RUS

Authors

Oksana Shulyatnikova

Anatoliy Godovalov

Gennadiy Rogozhnikov

Mihail Yakovlev

et al.

Kirill Batog

Elena Leushina

Oksana Shulyatnikova

Academic degree: doctor of medical sciences

Science rang: docent

Perm State Medical University named after Academician E. A. Vagner Professor of the Department · department of orthopedic stomatology · Russian Federation · Perm

Anatoliy Godovalov

Academic degree: candidate of medical sciences

Acad. E. A. Wagner Perm State Medical University Associate Professor of the Department · Department of Microbiology and Virology · Russian Federation · Perm

Gennadiy Rogozhnikov

Academic degree: doctor of medical sciences

Science rang: professor

Perm State Medical University named after Academician E. A. Vagner Professor of the Department · Orthopedic Dentistry Department · Russian Federation · Perm

Mihail Yakovlev

Permskiy gosudarstvennyy medicinskiy universitet im. akad. E.A. Vagnera Russian Federation · Пермь

FGBOU VO PGMU im. akademika E.A. Vagnera Minzdrava Rossii Russian Federation

Kirill Batog

FGBOU VO PGMU im. akademika E.A. Vagnera Minzdrava Rossii Russian Federation

Elena Leushina

Perm State medical University n.a. Academican E.A. Wagner Russian Federation · Perm

ABSTRACT

Subject. Changes in the activity of certain saliva enzymes, due to certain factors and in certain clinical conditions of the human body, can affect oral hygiene, as well as indirectly on the activity of the carious process. Of particular interest is the enzyme — alpha-amylase, which is due to its ability to cleave dextrans and levans, which are the basis of the matrix of the bacterial film. The article presents data on changes in the activity of saliva alpha-amylase in microecological disorders in the intestine and acute respiratory viral diseases, as well as its effect on the level of oral hygiene. The goal — the assessment of changes in the activity of saliva alpha-amylase in microecological disorders in the intestine and acute respiratory diseases, taking into account the level of oral hygiene. Methods. To determine the activity of alpha-amylase, a set of reagents "Amylase-Vital" was used according to the manufacturer's instructions, proportionally reducing the volume of reagents for the procedure in titration plates. The volunteers, divided into groups with severe acute respiratory syndrome, microecological intestinal disorders, and a control group, received mixed saliva and evaluated their oral hygiene status. Results. The inverse relationship between the severity of intoxication syndrome in severe acute respiratory syndrome and the level of saliva alpha-amylase activity is shown. In addition, a correlation was established between an increase in human body temperature and a decrease in the activity of alpha-amylase. There is also a link between the presence of decompensated intestinal dysbiosis in humans and the activity of the enzyme. The dependence between the decrease in the activity of the studied enzyme and the increase in biofilm formation on the organs of the oral cavity was revealed. Conclusions and Relevance. The conducted studies open up a promising direction for the development of additional diagnostic criteria based on the determination of the activity of saliva alpha-amylase. In addition, the data obtained on the deterioration of oral hygiene indicate the need for a comprehensive approach to the treatment of patients in this category with the mandatory involvement of a dentist.

KEYWORDS

saliva, alpha-amylase, biofilm, intestinal dysbiosis, severe acute respiratory syndrome, oral hygiene

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GOST

Shulyatnikova O. A., Godovalov A. P., Rogozhnikov G. I., Yakovlev M. V., Batog K. A., Leushina E. A. ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS // Actual problems in dentistry. 2021. no. 1. pp. 172-176. DOI: https://doi.org/10.18481/2077-7566-20-17-1-172-176. (Date of access 25.10.2026).

MLA

Oksana Shulyatnikova, Godovalov A. P., Rogozhnikov G. I., Yakovlev M. V., Batog K. A., Leushina E. A.. "ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS." Actual problems in dentistry 17.1 (2021): 172-176. DOI: https://doi.org/10.18481/2077-7566-20-17-1-172-176.

APA

Shulyatnikova O. A., Godovalov A. P., Rogozhnikov G. I., Yakovlev M. V., Batog K. A., Leushina E. A. (2021). ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS. Actual problems in dentistry, 17(1), 172-176. https://doi.org/10.18481/2077-7566-20-17-1-172-176

Chicago

Oksana Shulyatnikova, Godovalov A. P., Rogozhnikov G. I., Yakovlev M. V., Batog K. A., Leushina E. A.. "ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS." Actual problems in dentistry 17, no. 1 (2021): 172-176. https://doi.org/10.18481/2077-7566-20-17-1-172-176.

WIKI

{{cite journal | author = Shulyatnikova O. A., Godovalov A. P., Rogozhnikov G. I., Yakovlev M. V., Batog K. A., Leushina E. A. | title = ACTIVITY OF SALIV ALPHA AMYLASES AND LEVEL OF ORAL CAVITY HYGIENE UNDER DIFFERENT CLINICAL CONDITIONS | journal = Actual problems in dentistry | year = 2021 | volume = 17 | issue = 1 | pages = 172-176 | doi = 10.18481/2077-7566-20-17-1-172-176 }}

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