employee
Yekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
student
Yekaterinburg, Ekaterinburg, Russian Federation
employee
Yekaterinburg, Ekaterinburg, Russian Federation
employee
Bishkek, Kyrgyzstan
UDK 616.31 Стоматология. Заболевания ротовой полости и зубов
Introduction. Introduction. Primary hypothyroidism refers to a common pathological condition associated with thyroid hormone deficiency. Among all thyroid diseases, its share reaches 20%, while the detection rate tends to grow steadily every year in all age groups. An urgent task remains to study the dental status against the background of thyroid diseases developing as a result of iodine deficiency, as well as due to a relative shortage of thyroid hormones. The purpose of the work is to identify the relationship between the quality of the performed restorations and the properties of oral fluid in patients with primary hypothyroidism. Materials and methods. The main study cohort included 60 women with a primary diagnosis of primary hypothyroidism aged 44–59 years. The comparison group consisted of 30 patients without thyroid pathology, identical in sex and age. All patients were evaluated for salivary gland secretory activity, oral fluid properties, and quality of direct oral restorations performed. Results. In the main group of the study, a decrease in the salivation rate, an increase in the viscosity of the oral fluid and a shift in saliva pH to the acidic side relative to the results obtained in the comparison group were detected. Assessment of the quality of direct restorations performed showed an increase in the number of their insolvency in patients of the main group, relative to the comparison group. Discussion. Deficiency of thyroid hormones in primary hypothyroidism is accompanied by a change in the properties of the oral fluid and the quality of direct restorations performed in the oral cavity in the distant period. Conclusion. The identification of the relationship between dental and somatic health parameters will allow the development of a new treatment approach in patients with primary hypothyroidism.
primary hypothyroidism, salivation rate, salivary rn, salivary viscosity, direct restorations
1. Popovicheva O.O., Kiselev A.I., Mazlov A.M. Schitovidnaya zheleza, ee stroenie i klinicheskie proyavleniya gipotireoza. Evraziyskoe nauchnoe ob'edinenie. 2021;2-3(72):153-154. [O.O. Popovicheva, A.I. Kiselev, A.M. Mazlov. Thyroid gland, its structure and clinical manifestations of hypothyroidism. Eurasian Scientific Association. 2021;2-3(72):153-154. (In Russ.)]. https://elibrary.ru/item.asp?id=44886134
2. Nasvaliev Z.A., Zhurakulov M.Sh., Zhuraev Sh.B. Gipotireoz. «Science and Education» Scientific Journal. 2023;4(5):328-338. [Z.A. Nasvaliev, M.Sh. Zhurakulov, Sh.B. Zhuraev. Hypothyroidism. «Science and Education» Scientific Journal 2023;4(5):328-338. (In Russ.)]. https://cyberleninka.ru/article/n/gipotireoz
3. Bulgakova A.I., Hafizova A.S. Stomatologicheskiy status pacientov s gipotireozom (obzor literatury). Aktual'nye problemy i perspektivy razvitiya stomatologii v usloviyah Sbornik statey mezhregional'noy nauchno-prakticheskoy konferencii, posvyaschennoy 25-letiyu stomatologicheskogo otdeleniya Medicinskogo instituta FGAOU VO «Severo-Vostochnyy federal'nyy universitet imeni M.K. Ammosova». Yakutsk. 2021:162-164. [A.I. Bulgakova, A.S. Hafizova. Dental status of patients with hypothyroidism (literature review). Current problems and prospects for the development of dentistry in the context of a collection of articles of the interregional scientific and practical conference dedicated to the 25th anniversary of the dental department of the Medical Institute of the Northeastern Federal University named after M.K. Ammosov. Yakutsk. 2021:162-164. (In Russ.)]. https://elibrary.ru/iouqyk
4. D'yachenko S.V., Firsova I.V., Yakovlev A.T., Gavrikova L.M. Stomatologicheskiy status pozhilyh pacientov s gipofunkciey schitovidnoy zhelezy. Prikaspiyskiy vestnik mediciny i farmacii. 2021;2(2.):52-56. [S.V. Dyachenko, I.V. Firsova, A.T. Yakovlev, L.M. Gavrikova. Dental status of elderly patients with thyroid hypofunction. Caspian Bulletin of Medicine and Pharmacy. 2021;2(2.):52-56. (In Russ.)]. https://cyberleninka.ru/article/n/stomatologicheskiy-status-pozhilyh-patsientov-s-gipofunktsiey-schitovidnoy-zhelezy
5. Tishkov D.S. Osobennost' techeniya stomatologicheskih zabolevaniy u bol'nyh s gipo- i giperfunkciey gormonov schitovidnoy zhelezy. Regional'nyy vestnik. 2020;1(40):10. [D.S. Tishkov. The peculiarity of the course of dental diseases in patients with hypo- and hyperfunction of thyroid hormones. Regional Bulletin. 2020;1(40):10. (In Russ.)]. https://elibrary.ru/item.asp?edn=fsjyah
6. Islamova N.B. Chakkonov F.H. Izmeneniya v tkanyah i organah rta pri endokrinnyh zabolevaniyah. Aktual'nye voprosy stomatologii. 2021:320-326. [N.B. Islamova, F.H. Chakkonov. Changes in tissues and organs of the mouth in endocrine diseases. Topical issues of dentistry. 2021:320-326. (In Russ.)]. https://elibrary.ru/item.asp?id=45687246
7. Ganeev T.I., Kabirova M.F., Aver'yanov S.V., Kamilov F.H., Farshatova E.R., Kozlov V.N., Yunusov R.R., Ponomarev E.E. Stomatologicheskoe zdorov'e vzroslogo naseleniya na fone deficita obespechennosti yoda. Institut stomatologii. 2021;4(97):58-61. [T.I. Ganeev, M.F. Kabirova, S.V. Averyanov, F.H. Kamilov, E.R. Farshatova, V.N. Kozlov, R.R. Yunusov, E.E. Ponomarev. Dental health of the adult population against the background of iodine deficiency. Institute of Dentistry. 2021;4(97):58-61. (In Russ.)]. https://elibrary.ru/item.asp?id=50085799
8. Canava I.A., Bulgakova S.V., Melikova A.V., Zaharova N.O. Gipotireoz u pozhilyh. Klinicheskaya gerontologiya. 2021;27(3-4):75-81. [I.A. Tsanava, S.V. Bulgakova, A.V. Melikova, N.O. Zakharova. Hypothyroidism in the elderly. Clinical gerontology. 2021;27(3-4):75-81. (In Russ.)]. https://cyberleninka.ru/article/n/gipotireoz-u-pozhilyh
9. Verbovoy A.F., Sharonova L.A., Burakshaev S.A., Shuhorova Yu.A. Osobennosti stomatologicheskogo statusa pri endokrinnyh zabolevaniyah. Medicinskaya nauka i obrazovanie Urala. 2022;23(2(110)):183-189. [A.F. Verbovoy, L.A. Sharonova, S.A. Burakshaev, Yu.A. Shukhorova. Features of the dental status in endocrine diseases. Medical science and education of the Urals. 2022;23(2(110)):183-189. (In Russ.)]. https://elibrary.ru/item.asp?id=48700006
10. Rahmatova M.H., Tarinova M.V., Shigakova L.A. Vliyanie schitovidnoy zhelezy na sostoyanie zubochelyustnoy sistemy: literaturnyy obzor. Internauka. 2021;4-1(180):41-44. [M.H. Rakhmatova, M.V. Tarinova, L.A. Shigakova. The influence of the thyroid gland on the state of the dental system: a literary review. Internauka. 2021;4-1(180):41-44. (In Russ.)]. https://elibrary.ru/item.asp?id=44705933
11. Boldyreva Yu.V., Bragin A.V., Lebedev I.A. «Tipichnyy pacient» s gipotireozom (klinicheskiy sluchay). Ural'skiy medicinskiy zhurnal. 2020;10(193):35-39. [Yu.V. Boldyreva, A.V. Bragin, I.A. Lebedev. "A typical patient" with hypothyroidism (clinical case). Ural Medical Journal. 2020;10(193):35-39. (In Russ.)]. https://elibrary.ru/item.asp?id=44346802
12. Borzm A.M. et al. Diagnosis and treatment of hypothyroidism in old people: A new old challenge // Wiener Klinische Wochenschrift. – 2020;132(5-6):161-167. doi:https://doi.org/10.1007/s00508-019-01579-8.
13. Urgatz B., Razvi S. Subclinical hypothyroidism, outcomes and management guidelines : a narrative review and update of recent literature // Curr Med Res Opin. – 2023;39(3):351-365. doi:https://doi.org/10.1080/03007995.2023.2165811.
14. Ruderich F., Feldkamp J. Subklinische Hypothyreose [Subclinical hypothyroidism] // Dtsch Med Wochenschr. – 2022;147(6):289-294. DOI:https://doi.org/10.1055/a-1612-4816
15. Mohnacheva S.B., Moseeva M.V. Izmenenie slyunnyh zhelez u krys v eksperimente pri gipotireoze i metabolicheskom sindrome. Zdorov'e, demografiya, ekologiya finno-ugorskih narodov. 2020;3:72-74. [S.B. Mokhnacheva, M.V. Moseeva. Changes in salivary glands in rats in an experiment with hypothyroidism and metabolic syndrome. Health, demography, ecology of the Finno-Ugric peoples. 2020;3:72-74. (In Russ.)]. https://elibrary.ru/item.asp?id=44343534
16. Rabinovich O.F., Umarova K.V., Agapitova L.P. Zabolevaniya slizistoy obolochki polosti rta u pacientov s saharnym diabetom II tipa i patologiey schitovidnoy zhelezy. Klinicheskaya stomatologiya. 2018;4(88):6-9. [O.F. Rabinovich, K.V. Umarova, L.P. Agapitova. Diseases of the oral mucosa in patients with type II diabetes mellitus and thyroid pathology. Clinical dentistry. 2018;4(88):6-9. (In Russ.)]. https://elibrary.ru/item.asp?id=36517605
17. Sul'timova T.B., Kozlova M.V. Zabolevaniya slyunnyh zhelez pri endokrinopatiyah. Vestnik KGMA imeni I.K. Ahunbaeva. 2020;2(2):79-86. [T.B. Sultimova, M.V. Kozlova. Diseases of the salivary glands in endocrinopathies. Bulletin of the I.K. Akhunbayev KSMU. 2020;2(2):79-86. (In Russ.)]. https://elibrary.ru/item.asp?id=43922641
18. Borzuei S., Amjad S.V., Badiei M., Farmany A., Cheraghi Z. Invastigated salivary concentration of calcium ion in hypothyroidism // Health Sci Rep. – 2023;6(10):e1669. doi:https://doi.org/10.1002/hsr2.1669.
19. Naik M.M., Vaddandacoumara V. Qualitative and quantitative salivary changes and subjective oral dryness among patients with thyroid dysfunction // Indian J Dent Res. – 2018;29(1):16-21. doi:https://doi.org/10.4103/ijdr.IJDR_501_16.
20. Guseynova E.A. Rol' slyuny v razvitii kariesa. Byulleten' medicinskih internet – konferenciy. 2018;8(7):270. [E.A. Huseynova. The role of saliva in the development of caries. Bulletin of medical Internet conferences. 2018;8(7):270. (In Russ.)]. https://elibrary.ru/item.asp?id=35644500
21. Kasimova G.I. Epidemiologiya ocenka intensivnosti kariesa postoyannyh zubov u pacientov s gipotireozom. Central Asian Journal of Medical and Natural Science. 2024;5(1):552-558. [G.I. Kasimova. Epidemiology assessment of the intensity of caries of permanent teeth in patients with hypothyroidism. Central Asian Journal of Medical and Natural Science. 2024;5(1):552-558. (In Russ.)]. https://doi.org/10.17605/cajmns.v5i1.2369
22. Nazarova N., Ruzimurodova Z. Kliniko-funkcional'nye aspekty zabolevaniy parodonta i tverdyh tkaney zubov u bol'nyh s gipotireozom. Profilakticheskaya medicina i zdorov'e. 2022;1(1):83-91. [N. Nazarova, Z. Ruzimurodova. Clinical and functional aspects of periodontal diseases and dental hard tissues in patients with hypothyroidism. Preventive medicine and health. 2022;1(1):83-91. (In Russ.)]. https://elibrary.ru/mtvdve
23. Masyuk N.Yu., Gorodeckaya I.V. Korrelyacionnyy analiz svyazi urovnya yodsoderzhaschih tireoidnyh gormonov v krovi, aktivnosti karioznogo processa i mehanizmov ego vyzyvayuschih. Stomatologiya. Estetika. Innovacii. 2018;2(5):296-303. [N.Yu. Masyuk, I.V. Gorodetskaya. Correlation analysis of the relationship between the level of iodine-containing thyroid hormones in the blood, the activity of the carious process and the mechanisms causing it. Dentistry. Aesthetics. Innovation. 2018;2(5):296-303. (In Russ.)]. https://elibrary.ru/item.asp?id=35740731
24. Grebennikov Yu.A., Gol'berg N.D. Sostoyanie tverdyh tkaney zubov i rotovoy zhidkosti u sportsmenov plovcov. Sportivnaya medicina: nauka i praktika. 2021;11(1):19-23. [Yu.A. Grebennikov, N.D. Golberg. The condition of hard tissues of teeth and oral fluid in athletes swimmers. Sports medicine: science and practice. 2021;11(1):19-23. (In Russ.)]. https://doi.org/10.47529/2223-2524.2021.1.1
25. D'yachenko S.V., Firsova I.V., Gavrikova L.M. Sostoyanie tverdyh tkaney zubov u pozhilyh pacientov s gipofunkciey schitovidnoy zhelezy. Mediko-farmacevticheskiy zhurnal Pul's. 2021;23(10):43-49. [S.V. Dyachenko, I.V. Firsova, L.M. Gavrikova. The condition of hard dental tissues in elderly patients with hypofunction of the thyroid gland. Medical and pharmaceutical journal Pulse. 2021;23(10):43-49. (In Russ.)]. https://cyberleninka.ru/article/n/sostoyanie-tverdyh-tkaney-zubov-u-pozhilyh-patsientov-s-gipofunktsiey-schitovidnoy-zhelezy
