Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Samarkand, Uzbekistan
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
UDK 616.31 Стоматология. Заболевания ротовой полости и зубов
The subject of the study is human oral fluid. The goal is quantitative and qualitative assessment of the crystalline structure of the oral fluid of personal computer users using the theory of fractals. The task is to characterize qualitatively the crystals of the oral fluid of volunteers; apply a computer program to calculate the fractal dimension and area of oral fluid crystals. Methodology. Research work consists of two stages. In the first stage, a quantitative and qualitative assessment of the crystalline structure of users’ oral fluid was carried out over time without exposure to electromagnetic radiation from a computer. In the second stage, a quantitative and qualitative assessment of the crystalline structure of the users’ oral fluid in dynamics under the influence of electromagnetic radiation from a computer was performed. A laboratory analysis of oral fluid was performed according to physicochemical parameters: pH, buffer capacity, surface tension, total protein, inorganic phosphorus, ammonium, potassium, sodium, magnesium, calcium and α-amylase. The type of structure of saliva microcrystals was determined using the method of P.A. Leus. Additionally, the structure of representative crystals was assessed. A fractal analysis of crystals was carried out (calculation of the fractal dimension and area of the crystals). Results. Qualitative and quantitative assessment of the state of users' oral fluid over time without exposure to electromagnetic radiation from a computer did not reveal statistically significant changes in physicochemical parameters and crystal structure. Based on the results of the second stage of research, the negative effect of the computer’s electromagnetic field on the oral fluid of users was established. Assessment of the crystalline structure of oral fluid according to the method of P.A. Leus did not reveal any negative changes against the background of computer radiation. However, a visual assessment of the representative crystals showed that there are disturbances in the structure of the crystal structures as a result of their destruction and loss of the first and second order axes, which was confirmed by fractal analysis. Conclusion. The negative impact of laptop electromagnetic radiation on the oral fluid of users has been revealed. Qualitative and quantitative crystallographic methods are complementary. Integration of these methods in the form of a quantitative and qualitative assessment of the crystalline structure of human oral fluid will allow the doctor to expand diagnostic capabilities in the field of saliva diagnostics.
saliva diagnostics, computer program, oral fluid, crystal structure, fractal dimension, area
1. Yangyang Cui, Mengying Yang, Jia Zhu et al. Developments in diagnostic applications of saliva in human organ diseases // Medicine in Novel Technology and Devices. – 2022;13(100115):1-11. https://doi.org/10.1016/j.medntd.2022.100115
2. Leszczyński P., Sokalski J., Jerzy. The use of fractal analysis in medicine: A literature review // Dental and Medical Problems. – 2017;54:79-83. doi:https://doi.org/10.17219/dmp/67501
3. Mengyuan Song, Hao Bai, Ping Zhang et al. Promising applications of human-derived saliva biomarker testing in clinical diagnostics // International Journal of Oral Science. – 2023;135(5):1-17. https://doi.org/10.1038/s41368-022-00209-w
4. Simonyan L.F., Lomiashvili L.M., Stafeev A.A. i dr. Kolichestvenno-kachestvennaya harakteristika kristallicheskogo stroeniya rotovoy zhidkosti cheloveka s ispol'zovaniem teorii fraktalov. Chast' I. Problemy stomatologii. 2024;20(1):80-84. [L.A. Simonyan, L.M. Lomiashvili, A.A. Stafeev et al. Quantitative and qualitative characteristics of the crystal structure of human oral fluid using the theory of fractals. Part I. Actual Problems of dentistry. 2024;20(1):80-84. (In Russ.)]. DOIhttps://doi.org/10.18481/2077-7566-2024-20-1-80-84.
5. Lomiashvili L.M., Elendo M.B., Sedel'nikov V.V. i dr. Kristallografiya rotovoy zhidkosti kak indikator narusheniy sostoyanii polosti rta pol'zovateley personal'nym komp'yuterom. Aktual'nye voprosy stomatologii. XX Mezhdunarodnaya nauchno-prakticheskaya konferenciya, sbornik statey, Omsk, 04–06 marta 2014 goda. Omsk : Gosudarstvennoe byudzhetnoe obrazovatel'noe uchrezhdenie vysshego professional'nogo obrazovaniya «Omskaya gosudarstvennaya medicinskaya akademiya» Ministerstva zdravoohraneniya Rossiyskoy Federacii. 2014:91-93. [L.M. Lomiashvili, M.B. Elendo, V.V. Sedelnikov et al. Crystallography of oral fluid as an indicator of violations of the oral cavity of users of a personal computer. Current issues in dentistry. XX International Scientific and Practical Conference, collection of articles, Omsk, March 04–06, 2014. Omsk : State budgetary educational institution of higher professional education “Omsk State Medical Academy” of the Ministry of Health of the Russian Federation. 2014:91-93.(In Russ.)]. https://www.elibrary.ru/item.asp?id=25784060
6. Simonyan L.A., Lomiashvili L.M., Anisimova I. V. i dr. Metody ocenki mikrokristallizacii rotovoy zhidkosti (literaturnyy obzor). Institut stomatologii. 2022;1(94):90-92. [L.A. Simonyan, L.M. Lomiashvili, I.V. Anisimova et al. Methods for assessing microcrystallization of oral fluid (literature review). Institute of Dentistry. 2022;1(94):90-92. (In Russ.)]. https://www.elibrary.ru/item.asp?id=48213688
7. Mitronin A.V., Antonova O.A. Biomarkery smeshannoy slyuny kak indikatory sostoyaniya organizma. Rossiyskaya stomatologiya. 2022;15(1):61-62. [A.V. Mitronin, O.A. Antonova. Biomarkers of mixed saliva as indicators of the state of the body. Russian Dentistry. 2022;15(1):61-62. (In Russ.)]. DOIhttps://doi.org/10.17116/rosstomat20221501125.
8. Pohoden'ko-Chudakova I.O. Mikrokristallizaciya rotovoy zhidkosti v diagnostike, prognozirovanii razvitiya i techeniya hirurgicheskoy patologii chelyustno-licevoy oblasti. Vestnik Kyrgyzskoy gosudarstvennoy medicinskoy akademii imeni I.K. Ahunbaeva. 2022;2:48-57. [I.O. Pokhodenko-Chudakova. Microcrystallization of oral fluid in the diagnosis, prediction of the development and course of surgical pathology of the maxillofacial region. Bulletin of the Kyrgyz State Medical Academy named after I.K. Akhunbaeva. 2022;2:48-57. (In Russ.)]. DOIhttps://doi.org/10.54890/1694-6405_2022_2_48.
9. Skripkina G.I., Solonenko A.P., Garifullina A.Zh. Rotovaya zhidkost' i ee rol' v opredelenii urovnya zdorov'ya polosti rta. Ucheb. Posobie. Omsk : Izd-vo OmGM. 2016:48. [G.I. Skripkina, A.P. Solonenko, A.Zh. Garifullina. Oral fluid and its role in determining the level of oral health. Textbook. Manual. Omsk : Omsk State Medical University Publishing House. 2016:48. (In Russ.)]. http://weblib.omsk-osma.ru/fulltext/k552.html
10. Saratovkin D.D. Dendritnaya kristallizaciya. Moskva : Metallurgizdat. 1957:128. [D.D. Saratovkin. Dendritic crystallization. Moscow : Metallurgizdat. 1957:128. (In Russ.)]. https://urss.ru/cgi-bin/db.pl?lang=Ru&blang=ru&page=Book&id=75259
11. Sedel'nikov V.V. Strukturoobrazovanie kristallizuyuschihsya sistem pri modificirovanii ih ul'tradispersnymi poroshkami. Liteynoe proizvodstvo. 2005;1:2-5 ; 2005;2:2-6. [V.V. Sedelnikov. Structure formation of crystallizing systems when modifying them with ultrafine powders. Foundry production. 2005;1:2-5 ; 2005;2:2-6. (In Russ.)]. http://www.foundrymag.ru/mm_2011_01_bibl.html
12. Simonyan, L. A. Stabilizaciya pokazateley smeshannoy slyuny cheloveka pod vozdeystviem elektromagnitnogo izlucheniya personal'nogo komp'yutera. Problemy stomatologii. 2022;18(2):87-92. [L.A. Simonyan. Stabilization of indicators of mixed human saliva under the influence of electromagnetic radiation of a personal computer. Actual Problems in dentistry. 2022;18(2):87-92. (In Russ.)]. DOIhttps://doi.org/10.18481/2077-7566-2022-18-2-87-92.
13. Cherkasova M.S. Primenenie fraktalov v medicine. Molodoy uchenyy. 2019;8(246):175-177. [M.S. Cherkasova. Application of fractals in medicine. Young scientist. 2019;8(246):175-177. (In Russ.)]. https://moluch.ru/archive/246/56636/
14. Shabalin V.N., Shatohina S.N. Morfologiya biologicheskih zhidkostey cheloveka. Moskva. 2001:303. [V.N. Shabalin, S.N. Shatokhina. Morphology of human biological fluids. Moscow. 2001:303. (In Russ.)]. https://elibrary.ru/item.asp?id=21943409
15. Shatohina S.N. Funkcional'naya morfologiya biologicheskih zhidkostey - novoe napravlenie v klinicheskoy laboratornoy diagnostike. Al'manah klinicheskoy mediciny. 2008;18:50-56. [S.N. Shatokhina. Functional morphology of biological fluids - a new direction in clinical laboratory diagnostics. Almanac of Clinical Medicine. 2008;18:50-56. (In Russ.)]. https://cyberleninka.ru/article/n/funktsionalnaya-morfologiya-biologicheskih-zhidkostey-novoe-napravlenie-v-klinicheskoy-laboratornoy-diagnostike
