Kazan, Kazan, Russian Federation
Kazan, Kazan, Russian Federation
Kazan', Kazan, Russian Federation
Kazan', Kazan, Russian Federation
from 01.01.1998 to 01.01.2019
Kazan', Kazan, Russian Federation
UDK 616.31 Стоматология. Заболевания ротовой полости и зубов
Item. The review of literature devoted to the actual problem of maxillofacial surgery — processes of bone tissue regeneration in mandibular fractures is presented. The purpose of the study — to study and analyze the materials of publications on the processes of bone tissue regeneration in mandibular fractures. Methodology. The publications of domestic and foreign authors devoted to the processes of bone tissue regeneration in mandibular fractures were studied. The publications were analyzed using scientific search library databases: PubMed Central, Google, Cyberleninka, eLibrary. Materials were selected by keywords. Full-text articles were included in the search. Results. In domestic and foreign literature, the processes of restoration of bone structures of the maxillofacial region as an organism's response to damage have been studied and described in detail. It has been established that two processes are simultaneously launched: resorption of damaged osteocytes and formation of osteoid tissue, one of which may be predominant at the moment. Conclusions. The article presents modern data on the key moments of bone tissue regeneration in the region of the mandible. All stages of the reparative process in bone tissue are described at the cellular level, and information about the main mechanisms, pathways and cell types involved in bone tissue regeneration is presented in detail, taking into account the stage of osteogenesis. Knowledge of the regularities of biological processes in the bone tissue regeneration zone allows scientific search and development of effective methods of treatment of mandibular fractures.
fractur of the mandible, bone regeneration, reparative osteogenesis, bone repair process, ossification
1. Abdullaev Sh.Yu., Halilov A.A., Yusupova D.Z. Aspekty sovremennogo lecheniya perelomov nizhney chelyusti: obzor literatury. In Library. 2021;21(2):190-195. [Sh.Yu. Abdullaev, A.A. Halilov, D.Z. Yusupova. Aspects of modern treatment of mandibular fractures: a review of the literature. In Library. 2021;21(2):190-195. (In Russ.)]. https://journals.scinnovations.uz/index.php/aposo/article/view/225
2. Gil'manova G.S., Gasymzade D.K., Ksembaev S.S., Gil'manov A.A. Rasprostranennost' i etiologiya perelomov nizhney chelyusti. Problemy stomatologii. 2021;1(17): 20-25. [G.S. Gil'manova, D.K. Gasymzade, S.S. Ksembaev, A.A. Gil'manov. The prevalence and etiology of fractures of the mandible. Actual problems in dentistry. 2021;1(17):20-25. (In Russ.)]. https://doi.org/10.18481/2077-7566-20-17-1-20-25
3. Gololobov V.G. Zakonomernye processy posttravmaticheskogo osteogistogeneza. Morfologiya. 2019;155(2):83. [V.G. Gololobov. Typical processes of post-travmatic osteohistogenesis. Morphology. 2019;155(2):83. (In Russ.)]. https://www.elibrary.ru/item.asp?id=38173853&ysclid=lufbja4bxp470520662
4. Ezhov M.Yu., Ezhov I.Yu., Kashko A.K. i dr. Nereshennye voprosy regeneracii hryaschevoy i kostnoy tkani (obzorno-analiticheskaya stat'ya). Uspehi sovremennogo estestvoznaniya. 2015;5:126-131. [M.Y. Yezhov, I.Y. Yezhov, A.K.Kashko, A.Y. Kayumov, A.A. Zykin, S.A. Gerasimov. Unresolved issues of the cartilage and bone regeneration (review). Advances in current natural sciences. 2015;5:126-131. (In Russ.)]. https://elibrary.ru/item.asp?id=23875867
5. Zamay T.N., Tolmacheva T.V. Novye strategii regeneracii kostnoy tkani s pomosch'yu magnitomehanicheskoy transdukcii. Sibirskoe medicinskoe obozrenie. 2021;6:5-11. [T.N.Zamay, T.V. Tolmacheva. New strategies in bone tissue regeneration via application of magnetomechanical transduction. Siberian Medical Review. 2021;6:5-11. (In Russ.)]. doi:https://doi.org/10.20333/25000136-2021-6-5-11
6. Iordanishvili A., Muzykin M., Soldatov V. Zakonomernosti regeneracii kostnoy tkani. Stomatologicheskiy nauchno-obrazovatel'nyy zhurnal. 2019;2:21-29. [A.K.Iordanishvili, M.I. Muzikin, V.S. Soldatov. Regularities of bone tissue regeneration. Journal of dental scientific and education. 2019;2:21-29. (In Russ.)]. https://www.1spbgmu.ru/images/home/universitet/izdatelstvo/DentalScience/2011/DSE_1_2-2019.pdf?ysclid=lufbrydgkx744705642
7. Kostiv R.E., Kalinichenko S.G., Matveeva N.Yu. Troficheskie faktory rosta kostnoy tkani, ih morfogeneticheskaya harakteristika i klinicheskoe znachenie. Tihookeanskiy medicinskiy zhurnal. 2017;1:10-16. [R.E. Kostiv, S.G. Kalinichenko, N.Yu. Matveeva. Trophic factors of bone growth, their morphogenetic characterization and clinical significance. Pacific Medical Journal. 2017;1:10-16. (In Russ.)]. doi:https://doi.org/10.17238/PmJ1609-1175.2017.1.10-16
8. Kurzanov A.N., Ledvanov M.Yu., Bizenkova M.N. Vozmozhnosti primeneniya paratgormon-rodstvennogo proteina i drugih ligandov receptora PTH1R dlya optimizacii reparativnogo osteogeneza. Paratgormon-rodstvennyy protein. 2-e izd. Pererab. i dop. Moskva : Izdatel'skiy Dom "Akademiya Estestvoznaniya". 2020:569-625. [ A.N.Kurzanov, M.Yu. Levadnov, M.N.Bizenkova. Paratgormone-related protein. 2nd edition revised and supplemented. Moscow : Publishing House "Academy of Natural Sciences". 2020:569-625. (In Russ.)]. https://elibrary.ru/item.asp?id=44499424&ysclid=lufbxwqvmj604634252
9. Matchin A.A., Stadnikov A.A., Nosov E.V., Klevcov G.V. Reparativnye processy v tkanyah chelyustno-licevoy oblasti pri ispol'zovanii nanostrukturirovannogo titana. Zhurnal Medicina i innovacii. 2022;1:123-133. [A.A. Matchin, A.A. Stadnikov, E.V. Nosov, G.V. Klevtsov. Repaire processes in tissues of the maxillofacial area when using nanostructured titan. Journal of medicine and innovation. 2022;1:123-133. (In Russ.)]. https://inlibrary.uz/index.php/medicine_and_innovations /article/view/11768
10. Matchin A.A., Stadnikov A.A., Nosov E.V., Kiriakidi S.H. Eksperimental'no-morfologicheskoe obosnovanie primeneniya gipotalamicheskogo neyropeptida oksitocina pri lechenii perelomov nizhney chelyusti. Sovremennye tehnologii v chelyustno-licevoy hirurgii i hirurgicheskoy stomatologii. Materialy Regional'noy nauchno-prakticheskoy konferencii, posvyaschennoy 100-letiyu so dnya rozhdeniya professora, general-mayora medicinskoy sluzhby N.M. Aleksandrova. Sankt-Peterburg. 2023:62-67. [A.A. Matchin, A.A. Stadnikov, E.V. Nosov, S.Kh. Kiriakidi. Experimental and morphological substantiation of the use of the hypothalamic neuropeptide oxytocin in the treatment of mandibular fractures. Modern technologies in maxillofacial surgery and surgical dentistry. Materials of the Regional Scientific and Practical Conference dedicated to the 100th anniversary of the birth of Professor, Major General of the Medical Service N.M. Alexandrova. Saint Petersburg. 2023:62-67. (In Russ.)]. https://elibrary.ru/item.asp?id=56002431
11. Nikonorova V.G., Krishtop V.V., Rumyanceva T.A. Granulyacionnaya tkan' kak raznovidnost' soedinitel'nyh tkaney (obzor). Zhurn. med.-biol. issledovaniy. 2022;10(2):167-179. [V.G. Nikanorova, T.A.Krishtop. Granulation tissue as a type of connective tissues (Review). Journal of Medical and Biological Research. 2022;10(2):167-179. (In Russ.)]. doi: https://doi.org/10.37482/2687-1491-Z098
12. Nosov E.V., Blinova E.V., Matchin A.A., Stadnikov A.A. O reparativnyh processah v zone eksperimental'nogo pereloma nizhney chelyusti u zhivotnyh. Stomatologicheskaya vesna v Belgorode – 2022. Sbornik trudov Mezhdunarodnoy nauchno-prakticheskoy konferencii v ramkah mezhdunarodnogo stomatologicheskogo festivalya «Ploschadka bezopasnosti stomatologicheskogo pacienta», posvyaschennogo 100-letiyu Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova. Belgorod. 2022:173-175. [E.V. Nosov, E.V. Blinova, A.A. Matchin, A.A. Stadnikov. On reparative processes in the zone of experimental mandibular fracture in animals. Dental spring in Belgorod – 2022. Proceedings of the International Scientific and Practical Conference within the framework of the International Dental Festival "Dental Patient Safety Platform" dedicated to the 100th anniversary of the Moscow State Medical and Dental University named after A.I. Evdokimov. Belgorod. 2022:173-175. (In Russ.)]. https://elibrary.ru/pysceu?ysclid=lufdibi6zx433119173
13. Povernov P.A., Shibryaeva L.S. Mehanobiologicheskie aspekty zazhivleniya perelomov kostey s primeneniem biorazlagaemyh kostnyh implantatov. Aktual'nye problemy nauki i tehniki. Sbornik trudov po materialam Mezhdunarodnogo konkursa nauchno-issledovatel'skih rabot. Ufa. 2020:29-30. [P.A. Povernov, L.S. Shibryaeva. Mechanobiologic aspects of bone fracture healing using biodegradable bone implants. Actual problems of science and technology. Collection of works on the materials of the International competition of research works. Ufa. 2020:29-30. (In Russ.)]. https://elibrary.ru/item.asp?id= 43794081&ysclid=lufdj4jlh881196160
14. Sirak S.V., Andreev A.A. Regeneraciya kostnoy tkani pri perelomah nizhney chelyusti, oslozhnennyh travmaticheskim osteomielitom nespecificheskoy etiologii. Stomatolog. 2018;4(31):83-87. [S.V. Sirak, A.A. Andreev. Bone tissue regeneration in mandibular fractures complicated by traumatic osteomyelitis of nonspecific etiology. Dentist. 2018;4(31):83-87. (In Russ.)]. https://doi.org/10.32993/stomatologist.2018.4(31).15
15. Toboev G.V., Kokoev V.A., Kocoeva G.A. Ispol'zovanie medikamentoznoy korrekcii regeneratornoy aktivnosti kostnoy tkani pri perelomah nizhney chelyusti u lic s hronicheskoy alkogol'noy intoksikaciey. Medicina. Sociologiya. Filosofiya. Prikladnye issledovaniya. 2020;1:3-6. [G.V. Toboev, V.A. Kokoev, G.A. Kotsoeva. Use of medicinal correction of regenerative activity of bone tissue in fractures of the lower jaw in persons with chronic alcohol intoxication. Medicine. Sociology. Philosophy. Applied research. 2020;1:3-6. (In Russ.)]. https://medsociofil.ru/upload/iblock/c6e/%D0%9C%D0%A1%D0%A4_01_2020_FIN.pdf
16. Uruzbaev R.M., Silant'eva T.A., Gorbach E.N. i dr. Regenerativnye svoystva tkaney i organov, faktory uskoreniya reparativnyh processov (obzor literatury). Medicinskaya nauka i obrazovanie Urala. 2017;18(1):171-178. [R.M. Uruzbaev, T.A. Silanteva, E.N. Gorbach, V.G.Bychkov, E.A. Yuzhakova. Regenerativ properties of tissues and organs, factors of improvement of reparative processes (review). Medical science and education in the Urals. 2017;18(1):171-178. (In Russ.)]. https://elibrary.ru/item.asp?id=36455733&ysclid=lufdpk3c1d198708168
17. Yushkov B.G. Kletki immunnoy sistemy i regulyaciya regeneracii. Byulleten' sibirskoy mediciny. 2017;16(4):94-105. [B.G. Yushkov. Immune system and regulation of regeneration. Bulletin of Siberian Medicine. 2017;16(4):94-105. (In Russ.)]. https://cyberleninka.ru/article/n/kletki-immunnoy-sistemy-i-regulyatsiya-regeneratsii?ysclid=lufdtqwlm343484465
18. Antúnez-Conde R., Salmerón J.I., Díez-Montiel A. et al. Mandibular reconstruction with fibula flap and dental implants through virtual surgical planning and three different techniques: Double-barrel flap, implant dynamic navigation and CAD/CAM mesh with iliac crest graft // Front. Oncol. – 2021;11:719712. doi:https://doi.org/10.3389/fonc.2021.719712. eCollection 2021.
19. Bosch-Rué È., Díez-Tercero L., Buitrago J.O., Castro E., Pérez R.A. Angiogenic and immunomodulation role of ions for initial stages of bone tissue regeneration // Acta Biomater. – 2023;166:14-41. doi:https://doi.org/10.1016/j.actbio.2023.06.001.
20. Duda G.N., Geissler S., Checa S. et al. The decisive early phase of bone regeneration // Nat. Rev. Rheumatol. – 2023;19(2):78-95. doi:https://doi.org/10.1038/s41584-022-00887-0.
21. Mackey A.L., Kjaer M. Connective tissue regeneration in skeletal muscle after eccentric contraction-induced injury // J. Appl. Physiol. – 2017;122(3):533-540. doi:https://doi.org/10.1152/japplphysiol.00577.2016.
22. Marcio M.B., Adalberto L.R. Bone Regeneration and Repair Materials // J Funct Biomater. – 2024;21;15(3):78. doi:https://doi.org/10.3390/jfb15030078.
23. Nambiar J., Sonali J., Samit Kumar N. Strategies for Enhancing Vascularization of Biomaterial-Based Scaffold in Bone Regeneration // Chem Rec. – 2022;22(6):202200008. doi:https://doi.org/10.1002/tcr.202200008.
24. Reinke J.M., Sorg H. Wound Repair and Regeneration // European Surical Research. – 2012;49(1):35-43. https://doi.org/10.1159/000339613
25. Schlickewei C.W., Kleinertz H., Thiesen D.M. et al. Current and future concepts for the treatment of impaired fracture healing // Int. J. Mol. Sci. – 2019;20(22):5805. doi:https://doi.org/10.3390/ijms20225805.
26. Soares A.P., Fischer H., Aydin S. et al. Uncovering the unique characteristics of the mandible to improve clinical approaches to mandibular regeneration // Front. Physiol. – 2023;14:1152301. doi:https://doi.org/10.3389/fphys.2023.1152301.
27. Vermeulen S., Tahmasebi Z., Habibovic P. Birgani Biomaterial-induced pathway modulation for bone regeneration // Biomaterials. – 2022;283:121431. doi:https://doi.org/10.1016/j.biomaterials.2022.121431.
28. Yanfeng T., Jianlin C., Yunbiao Z. Experimental study on accelerated healing of jaw fracture using gelatin sponge compound growth factor // Hua Xi Kou Qiang Yi Xue Za Zhi. – 2017;35(5):506-509. doi:https://doi.org/10.7518/hxkq.2017.05.012.11
