Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
Yekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
UDK 616.31 Стоматология. Заболевания ротовой полости и зубов
Subject. The subject of this study is the dental status of young patients. Objectives. The objective of this study is to conduct a clinical and laboratory study to substantiate application of therapeutic and prophylactic toothpaste with plant extract in young patients in the area of prevention of dental diseases based on assessment of cleansing, rheological and organoleptic parameters of the toothpaste and resulting changes in the nonspecific resistance of the oral cavity. Methodology. The study was conducted by the Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases, the Department of General Chemistry of the Ural State Medical University, the Department of Controlled Systems Modeling of the Ural Federal University. The study group comprised 26 volunteer students of the Faculty of Dentistry (8 young men, 18 young women) aged between 19 and 24 years old. The dental examination of patients included the analysis of complaints and anamnesis data, examination of the oral cavity, the analysis of the intensity of caries (according to the DMFT index). The analysis of cleansing effect of SPLAT Special Love tooth paste with plant extract was done by determination of the oral hygiene index (OHI, Greene, Vermillion, 1964), and the qualitative analysis of saliva. Dental records were made. Integral assessment of non-specific resistance of the oral cavity was studied using microbial cell adsorption reaction by epithelial cells. The organoleptic properties of the tooth paste were determined using participants’ taste testing survey questions. Statistical analysis of data was made using the software package Vortex 5.0 and MS Excel together with a set of tools for medical statistics. The representative values of data were arithmetic means and the standard error of the mean (M ± m). The statistical significance was assessed using Student’s t-distribution. The results were considered significantly different at p ≤ 0.05. Conclusions. The research results showed the increase in nonspecific resistance of the oral cavity, restoration of the receptors in epithelial cells and improvement of epithelium adsorption after application of SPLAT "Special LOVE" tooth paste with plant extract on the oral mucosa. It positively influences metabolism of the oral cavity. The tooth paste promotes changes to the physical and chemical parameters such as the lower surface tension of saliva. The organoleptic properties of the experimental tooth paste were highly ranked by the volunteers. The highest scores were given to parameters like “Flavor” (10 points), “Scent” (10 points) and “Consistency” (9.8 points).
oral fluid, nonspecific resistance, microbial cell adsorption reaction by epithelial cells, organoleptic properties of toothpaste, stomatology
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