STUDYING THE REMINERALIZATION OF HARD DENTAL TISSUE IN PATIENTS AFTER RADIATION THERAPY ON THE NEWLY FORMED MAXILLOFACIAL AREA USING THE RAMAN FLUORESCENCE METHOD
Abstract and keywords
Abstract (English):
Subject. Mineralization of hard dental tissues and its correction in patients after radiation therapy for malignant neoplasms. Objectives. To develop a method for remineralization of hard dental tissues in patients after radiation therapy for neoplasms of the maxillofacial area using Raman fluorescence spectroscopy. Methodology. The study was conducted on a group of people who had previously received radiation therapy for malignant neoplasms of the head and neck, matched by gender and age, who voluntarily agreed to take part in it. The main group consisted of 20 people who underwent the proposed remineralization complex. Comparison group – without using the proposed complex. A study of Raman fluorescence of teeth was carried out using the InSpectrum computer in three areas (neck, equator, incisal edge) in patients before and after correction. Results. Raman fluorescence diagnostics of the tooth surface made it possible to clearly see the difference in mineralization in digitized indicators. The data for patients in the main group after correction of mineralization (y = 304, x = 963 cm-1) are higher than for patients in the comparison group (y = 287, x = 963 cm-1). Conclusion. In different areas of the tooth surface, the level of mineralization of hard tissues differs: neck (216 ± 0.019, x = 963 cm-1), equator (389 ± 0.024, x = 963 cm-1), cutting edge (282 ± 0.016, x = 963 cm-1). The Raman fluorescence diagnostic method allows you to monitor changes in mineralization. The developed method of remineralization of hard dental tissues in patients after radiation therapy for neoplasms of the maxillofacial area using Raman fluorescence spectroscopy makes it possible to influence mineralization and is recommended for further research to prevent the development of radiation caries

Keywords:
radiation caries, mineralization of hard tissues, Raman fluorescence, dentistry, radiation therapy, oncology
References

1. Tursun-zade R.T. Ocenka rasprostranennosti zlokachestvennyh novoobrazovaniy v Rossii s primeneniem modeli zabolevaemost'-smertnost'. Demograficheskoe obozrenie. 2018;5(3):103-126. [R.T.ursun-Zade. An evaluation of the prevalence of malignant neoplasms in Russia using an incidence-mortality model. Demographic survey. 2018;5(3):103-126. (In Russ.)]. https://doi.org/10.17323/demreview.v5i3.8137

2. Aleksandrov M.T., Margaryan E.G. Primenenie lazernyh tehnologiy v klinike terapevticheskoy stomatologii (obosnovanie, vozmozhnosti, perspektivy). Rossiyskaya stomatologiya. 2017;10(3):31-36. [M.T. Alexandrov, E.G. Margaryan. Laser technique application in therapeutic dentistry in clinic (rationale, possibilities, perspectives). Russian Stomatology. 2017;10(3):31-36. (In Russ.)]. https://doi.org/10.17116/rosstomat201710331-36

3. Aleksandrov M.T., Kukushkin V.I., Polyakova M.A., Novozhilova N.E., Babina K.S., Arakelyan M.G., Bagramova G.E., Pashkov E.P., Dmitrieva E.F. Raman-flyuorescentnye harakteristiki tverdyh tkaney zubov i ih klinicheskoe znachenie. Rossiyskiy stomatologicheskiy zhurnal. 2018;22(6):276-280. [M.T. Aleksandrov, V.I. Kukushkin, M.A. Polyakova, N.E. Novozhilova, K.S. Babina, M.G. Arakelyan, G.E. Bagramova, E.P. Pashkov, E.F. Dmitrieva. Raman fluorescence characteristics of hard dental tissues and their clinical significance. Russian Dental Journal. 2018;22(6):276-280. (In Russ.)]. https://doi.org/10.18821/1728-2802-2018-22-6-276-280

4. Nurieva N.S., Belyakov G.I. Issledovanie mineralizacii tverdyh tkaney zubov, porazhennyh luchevym kariesom, s pomosch'yu metoda raman-flyuorescentnoy diagnostiki. Problemy stomatologii. 2022;18(4):36-40. [N.S. Nurieva, G.I. Belyakov. Study of the mineralization of hard tissues of the teeth affected by radiation caries using the method of raman fluorescent diagnosis. Actual problems in dentistry. 2022;18(4):36-40. (In Russ.)]. https://doi.org/10.18481/2077-7566-2022-18-4-30-34

5. Magsumova O.A., Polkanova V.A., Timchenko E.V., Volova L.T. Ramanovskaya spektroskopiya i ee primenenie v stomatologii. Stomatologiya. 2021;100(4):137-142.[O.A. Magsumova, V.A. Polkanova, E.V. Timchenko, L.T. Volova. Raman spectroscopy and its application in different areas of medicine. Stomatologiya. 2021;100(4):137-142. (In Russ.)]. https://doi.org/10.17116/stomat2021100041137

6. Bazhutova I.V., Magsumova O.A., Frolov O.O., Timchenko E.V., Timchenko P.E., Trunin D.A., Komlev S.S., Polkanova V.A. Ocenka organicheskogo i mineral'nogo sostava emali zubov metodom ramanovskoy spektroskopii: eksperimental'noe nerandomizirovannoe issledovanie. Kubanskiy nauchnyy medicinskiy vestnik. 2021;28(4):118-132. [I.V. Bazhutova, O.A. Magsumova, O.O. Frolov, E.V. Timchenko, P.E. Timchenko, D.A. Trunin, S.S. Komlev, V.A. Polkanova. Raman spectroscopy analysis of dental enamel organic and mineral composition: an experimental non-randomised study. Kuban Scientific Medical Bulletin. 2021;28(4):118-132. (In Russ.)]. https://doi.org/10.25207/1608-6228-2021-28-4-118-132

7. Magsumova O.A. Ocenka izmeneniy kislotoustoychivosti i mineral'nogo sostava emali pri himicheskom otbelivanii zubov. Klinicheskaya stomatologiya. 2022;25(1):13-19. [O.A. Magsumova. Assessment of changes in acid resistance and mineral composition of enamel during chemical teeth whitening. Clinical dentistry. 2022;25(1):13-19. (In Russ.)]. DOI:https://doi.org/10.37988/1811-153X_2022_1_13

8. Bazhutova I.V., Magsumova O.A., Frolov O.O., Timchenko E.V., Timchenko P.E., Trunin D.A., Komlev S.S., Polkanova V.A. Ocenka organicheskogo i mineral'nogo sostava emali zubov metodom ramanovskoy spektroskopii: eksperimental'noe nerandomizirovannoe issledovanie. Kubanskiy nauchnyy medicinskiy vestnik. 2021;28(4):118-132. [I.V. Bazhutova, O.A. Magsumova, O.O. Frolov, E.V. Timchenko, P.E. Timchenko, D.A. Trunin, S.S. Komlev, V.A. Polkanova. Raman spectroscopy analysis of dental enamel organic and mineral composition: an experimental non-randomised study. Kuban Scientific Medical Bulletin. 2021;28(4):118-132. (In Russ.)]. https://doi.org/10.25207/1608-6228-2021-28-4-118-132

9. Cecilia Carlota Barrera Ortega. América Vázquez-Olmos, Roberto Ysaac Sato Berrú, Miguel Araiza. Study of Demineralized Dental Enamel Treated with Different Fluorinated Compounds by Raman Spectroscopy // Journal of Biomedical Engineering. - 2020;10(5):635-638. DOIhttps://doi.org/10.31661/jbpe.v0i0.2003-1089


Login or Create
* Forgot password?