from 01.01.2018 until now
Moscow, Moscow, Russian Federation
from 01.01.2013 until now
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
from 01.01.2017 until now
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
UDK 616 Патология. Клиническая медицина
Subject. The periimplantitis management and prophylaxis technique using xenogenic collagen gel and laser technique, analysis of their results. Aim. To evaluate the effect of periimplantitis management and prophylaxis with xenogenic collagen gel and laser technique. Methodology. The study was conducted on the basis of Sechenov University from 2020 to 2022. The study included ten patients with diagnosed peri-implantitis (age range 28–45 years, median is 35 years). All patients underwent professional hygiene followed by division into 2 groups by random sampling: patients of group 1 were injected with xenogenic collagen gel in the area of the peri-implant pocket and in the soft tissues around the dental implant in the area of alveolar bone resorption, patients of group 2 were subjected to laser bactericidal treatment of peri-implant pockets. The results were evaluated by the depth of probing of the peri-implant pocket and the clinical symptoms of the disease, the presence of adverse outcomes after the application of the techniques. Results. During 12 months of observation, a decrease in the depth of the peri-implant pocket during probing was noted by an average of 3 mm from the initial depth in both groups (p < 0.05), an increase in the volume of soft tissues around the implants, mainly when xenogenic gel was used (p < 0.05). Conclusions. Xenogenic collagen gel and laser microbiocidal treatment of peri-implant pockets may be an alternative treatment for peri-implantitis after full-fledged randomized clinical multicenter trials.
dental implants, peri-implantitis, xenogenic collagen gel, peri-implantitis treatment, diode laser, laser curettage
1. Machtei E.E. From Periodontitis to Periimplantitis-the Quest for the Missing Link // Current Oral Health Reports. - 2020;7:72-78. https://doi.org/10.1007/s40496-020-00252-8
2. Heitz-Mayfield L.J., Heitz F., Lang N.P. Implant Disease Risk Assessment IDRA-a tool for preventing peri-implant disease // Clinical oral implants research. - 2020;31:397-403. https://doi.org/10.1111/clr.13585
3. Mayer Y., Ginesin, O., Horwitz J. A nonsurgical treatment of peri-implantitis using mechanic, antiseptic and anti-inflammatory treatment: 1-year follow-up // Clinical and experimental dental research. - 2020;6(4):478-485. doi:https://doi.org/10.1002/cre2.286.
4. Jepsen S. New classification of periodontal and peri-implant diseases and conditions // Endodontic Practice Today. - 2020;14(1):19-24. https://doi.org/10.1111/jcpe.12935
5. Berglundh T., Jepsen S., Stadlinger B., Terheyden H. Peri-implantitis and its prevention // Clinical oral implants research. - 2019;30:150-155. https://doi.org/10.1111/clr.13401
6. Berglundh T.,Armitage G., Araujo M.G., Avila-Ortiz G., Blanco J., Camargo P.M., Hämmerle C.H. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions // Journal of Periodontology. - 2018;89:313-318. https://doi.org/10.1002/JPER.17-0739
7. Dreyer H., Grischke J., Tiede C., Eberhard J., Schweitzer A., Toikkanen S.E., Glöckner S., Krause G., Stiesch M. Epidemiology and risk factors of peri-implantitis: A systematic review // J Periodontal Res. - 2018;53(5):657-681. doi:https://doi.org/10.1111/jre.12562.
8. Derks J., Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology // J Clin Periodontol. - 2015;42(16):158-171. doi:https://doi.org/10.1111/jcpe.12334.
9. Meyle J., Casado P., Fourmousis I., Kumar P., Quirynen M., Salvi G.E. General genetic and acquired risk factors, and prevalence of peri-implant diseases-Consensus report of working group 1 // International Dental Journal. - 2019;69:3-6. https://doi.org/10.1111/idj.12489
10. Francetti L., Cavalli N., Taschieri S., Corbella S. Ten years follow-up retrospective study on implant survival rates and prevalence of peri-implantitis in implant-supported full-arch rehabilitations // Clinical oral implants research. - 2019; 30(3): 252-260. doi:https://doi.org/10.1111/clr.13411.
11. Mordini L., Sun N., Chang N., De Guzman J.-P., Generali L., Consolo U. Peri-Implantitis Regenerative Therapy: A Review // Biology. - 2021;10(8):773. https://doi.org/10.3390/biology10080773
12. Almohandes A., Carcuac O., Abrahamsson I., Lund H., Berglundh T. Re-osseointegration following reconstructive surgical therapy of experimental peri-implantitis. A pre-clinical in vivo study // Clin Oral Impl Res. - 2019;30:447-456. https://doi.org/10.1111/clr.13430
13. Roccuzzo M, Gaudioso L., Lungo M., Dalmasso P. Surgical therapy of single peri-implantitis intrabony defects, by means of deproteinized bovine bone mineral with 10% collagen // J. Clin. Periodontol. - 2016;43:311-318. doi:https://doi.org/10.1111/jcpe.12516.
14. Hattori S., Adachi E., Ebihara T., Shirai T., Someki I., Irie S. Alkali-treated collagen retained the triple helical conformation and the ligand activity for the cell adhesion via alpha2beta1 integrin // J Biochem. - 1999;125(4):676-684. doi:https://doi.org/10.1093/oxfordjournals.jbchem.a022336.
15. Renvert S., Persson G.R., Pirih F.Q., Camargo P.M. Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations // Journal of clinical periodontology. - 2018;45:278-285. doi:https://doi.org/10.1002/JPER.17-0588.
16. Rubnikovich S.P., Denisova Y.L., Vladimirskaya T.E., Andreyeva V.A., Kvacheva Z.B., Panasenkova G.Y., Volotovsky I.D. Regenerative cell technologies for gingival recession treatment // Sovremennye tehnologii v medicine. - 2018;10(4):94-102. https://cyberleninka.ru/article/n/regenerative-cell-technologies-for-gingival-recession-treatment
17. Demyanenko I.A., Kalmykova N.V., Melnikova S.V., Tretyakova A.V., Marchenko A.I., Mikhina L.V., Suslov A.P. The study of allergenic and genotoxic effects of the medical device" resorbable collagen material" collost®", gel" in the pre-clinical models in vivo // Drug development & registration. - 2017;4:256-261. https://www.pharmjournal.ru/jour/article/view/525?locale=en_US
18. Budkevich L.I., Mirzoyan G.V., Gabitov R.B., Brazol M.A., Salistyj P.V., Chikinev Y.V., Glutkin A.V. Collost bioplastic collagen material for the treatment of burns // Sovremennye tehnologii v medicine. - 2020;12(1):92-96. doi:https://doi.org/10.17691/stm2020.12.1.12
19. Andreev-Andrievskiy A.A., Bolgarina A.A., Manskih V.N., Gabitov R.B., Lagereva E.A., Fadeeva O.V., Telyatnikova E.V., Scherbakova V.S. Mehanizmy ranozazhivlyayuschego deystviya nativnogo kollagena I tipa v modeli ishemizirovannyh polnosloynyh ran kozhi na primere medicinskogo izdeliya «Kollost». (Chast' I). Hirurgiya. Zhurnal im. N.I. Pirogova. 2020;(10):79-87. [A.A. Andreev-Andrievsky, A.A. Bolgarina, V.N. Manskikh, R.B. Gabitov, E.A. Lagereva, O.V. Fadeeva, E.V. Telyatnikova, V.S. Shcherbakova. Mechanisms of the wound-healing action of native collagen type I in ischemic model full-thickness skin wounds on the example - medical devices Collost «(part I). Pirogov Russian Journal of Surgery. Khirurgiya. Zurnal im. N.I. Pirogova. 2020;(10):79-87. (In Russ.)]. https://doi.org/10.17116/hirurgia202010179
20. Lima R.P.E., Abreu L.G., Belém F.V., de Mattos Pereira G.H., Brant R.A., Costa F.O. Is implantoplasty efficacious at treating peri-implantitis? a systematic review and meta-analysis // Journal of Oral and Maxillofacial Surgery. - 2021;79(11):2270-2279. https://doi.org/10.1016/j.joms.2021.06.015
21. Figuero E., Graziani F., Sanz I., Herrera D., Sanz M. Management of peri-implant mucositis and peri-implantitis // Periodontol 2000. - 2014;66:255-273. https://doi.org/10.1111/prd.12049
22. Bianchini M.A., Galarraga-Vinueza M.E., Apaza-Bedoya K., De Souza J.M., Magini R., Schwarz F. Two to six-year disease resolution and marginal bone stability rates of a modified resective-implantoplasty therapy in 32 peri-implantitis cases // Clin Implant Dent Relat Res. - 2019;21:758-765. https://doi.org/10.1111/cid.12773
23. Pilar Valderrama, Thomas G. Wilson Jr, Detoxification of Implant Surfaces Affected by Peri-Implant Disease: An Overview of Surgical Methods // International Journal of Dentistry. 2013;2013:9. https://doi.org/10.1155/2013/740680
24. Matarasso S., Iorio Siciliano V., Aglietta M., Andreuccetti G., Salvi G.E. Clinical and radiographic outcomes of a combined resective and regenerative approach in the treatment of peri-implantitis: a prospective case series // Clin. Oral Impl. Res. - 2014;25:761-767. doi:https://doi.org/10.1111/clr.12183
25. Schwarz F., John G., Schmucker A., Sahm N., Becker J. Combined surgical therapy of advanced peri-implantitis evaluating two methods of surface decontamination: a 7-year follow-up observation // J Clin Periodontol. - 2017;44:337-342. doi:https://doi.org/10.1111/jcpe.12648.
