Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
employee from 01.01.2004 until now
Ufa, Ufa, Russian Federation
employee from 01.01.1983 until now
Ufa, Ufa, Russian Federation
employee
Ufa, Russian Federation
Ufa, Ufa, Russian Federation
employee from 01.01.1993 until now
Ufa, Ufa, Russian Federation
student
Ufa, Ufa, Russian Federation
The study of the pathogenesis of enamel demineralization in children living in a city with ecotoxicants is an urgent task of modern dentistry. We examined 183 schoolchildren aged 7 and 12 in Ufa. The children were divided into groups depending on where they live. The first group included 94 children from an area located in an industrial district with an environmentally unfavorable situation. The second group (control) included 89 schoolchildren living in an ecologically good district of the city of Ufa. We studied the content of free calcium in the saliva of schoolchildren in two districts of the city of Ufa. When determining the activity of caries according to Vinogradova T.F. (I, II, III degree) among 7 and 12-year-old children, we did not reveal a high correlation between the district where the children live and the concentration of free calcium in the oral fluid. In the mixed saliva of 7-year-old schoolchildren of the first and second groups, the concentration of free calcium was 0.645 ± 0.018 and 0.638 ± 0.011 mm/l (p > 0.05), in 12-year-olds it was 0.603 ± 0.050 and 0.597 ± 0.040 mm/l (p > 0.05). In the industrial district, we noted the maximum increase in free calcium at the III degree of caries activity. This indicator was 0.851 ± 0.006 mmol/l (p < 0.001) in 7-year-old children, and 0.760 ± 0.005 mmol/l in 12-year-old schoolchildren (p < 0.001). While in the district without ecotoxicants, free calcium in 7-year-old schoolchildren was 0.846 ± 0.026 mmol/l (p < 0.001), and in 12-year-old children it was 0.774 ± 0.010 mmol/l (p < 0.001). Thus, the third degree of caries activity is highly correlated with an increase in the concentration of free calcium in saliva, which is proved by studies of oral fluid in schoolchildren from different districts of Ufa.
free calcium, ionized calcium, caries, saliva, oral fluid, ecotoxicants
1. Zyryanov B.N., Gamzatov R.G. Vliyanie razlichnyh sposobov pervichnoy patogeneticheskoy profilaktiki kariesa zubov na mineral'nyy sostav polosti rta u rabochih-neftyanikov severa tomskoy oblasti. Problemy stomatologii. 2016;3:18-22. [B.N. Zyryanov, R.G. Gamzatov. Influence of various methods of primary pathogenetic prevention of dental caries on the mineral composition of the oral cavity in oil workers in the north of the Tomsk region. Actual problems in dentistry. 2016;3:18-22. (In Russ.)]. DOI: https://doi.org/10.18481/2077-7566-2016-12-18-22.
2. Ermishina E.Yu., Elovikova T.M., Sablina S.N., Grigor'ev S.S., Karaseva V.V., Chagay A.A., Koscheev A.S. Analiz izmeneniy fiziko-himicheskih svoystv smeshannoy slyuny molodyh lyudey pod vozdeystviem zhidkih sredstv gigieny. Problemy stomatologii. 2021;4:50-55. [E.Yu. Ermishina, T.M. Elovikova, S.N. Sablina, S.S. Grigoriev, V.V. Karaseva, A.A. Chagai, A.S. Koshcheev. Analysis of changes in the physicochemical properties of mixed saliva of young people under the influence of liquid hygiene products. Actual problems in dentistry. 2021;4:50-55. (In Russ.)]. DOI: https://doi.org/10.18481/2077-7566-21-17-4-50-55.
3. Leont'ev V.K., Pitaeva A.N., Skripkina G.I., Adkina G.V. Vliyanie sostava i svoystv rotovoy zhidkosti na energeticheskoe vzaimodeystvie v sisteme emal'-slyuna. Materialy XXIV Mezhdunarodnogo yubileynogo simpoziuma "Innovacionnye tehnologii v stomatologii", posvyaschennogo 60-letiyu stomatologicheskogo fakul'teta Omskogo Gosudarstvennogo Medicinskogo Universiteta. 2017:240-243. [V.K. Leontiev, A.N. Pitaeva, G.I. Skripkina, G.V. Adkina. Influence of the composition and properties of the oral fluid on the energy interaction in the enamel-saliva system. Materials of the XXIV International Anniversary Symposium "Innovative Technologies in Dentistry", dedicated to the 60th anniversary of the Faculty of Dentistry of Omsk State Medical University. 2017:240-243. (In Russ.)]. https://www.elibrary.ru/item.asp?id=32365103
4. Mityaeva T.S., Skripkina G.I., Ekimov E.V., Mackieva O.V. Vozmozhnost' prognozirovaniya kariesa zubov u detey v period smennogo prikusa. Problemy stomatologii. 2020;16(3):113-122. [T.S. Mityaeva, G.I. Skripkina, E.V. Ekimov, O.V. Matskieva. The possibility of predicting dental caries in children during mixed dentition. Actual problems in dentistry. 2020;16(3):113-122. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44153731
5. Nasretdinova N.Yu., Mandra Yu.V., Bazarnyy V.V., Kotikova A.Yu., Dimitrova Yu.V., Zhegalina N.M., Sorokoumova D.V., Vlasova M.I., Boldyrev Yu.A. Ocenka vliyaniya lechebno-profilakticheskih zubnyh past na sozrevanie emali v aspekte vozrasta i stepeni aktivnosti kariesa u shkol'nikov 6-7, 12, 15 let. Problemy stomatologii. 2021;2:115-120. [N.Yu. Nasretdinova, Yu.V. Mandra, V.V. Bazarny, A.Yu. Kotikova, Yu.V. Dimitrova, N.M. Zhegalina, D.V. Sorokoumova, M.I. Vlasova, Yu.A. Boldyrev. Evaluation of the effect of therapeutic and prophylactic toothpastes on the maturation of enamel in terms of age and degree of caries activity in schoolchildren aged 6-7, 12, 15 years. Actual problems in dentistry. 2021;2:115-120. (In Russ.)]. DOI: https://doi.org/10.18481/2077-7566-20-17-2-115-120.
6. Samatova R.Z. Stomatologicheskiy status i mineral'nyy sostav tverdyh tkaney zubov u detey v zavisimosti ot urovnya antropogennoy nagruzki. Problemy stomatologii. 2021;17(3):82-87. [R.Z. Samatova. Dental status and mineral composition of hard dental tissues in children depending on the level of anthropogenic load. Actual problems in dentistry. 2021;17(3):82-87. (In Russ.)]. https://www.elibrary.ru/item.asp?id=47176560
7. Chuykin O.S., Shtan'ko M.I., Kuchuk K.N. Gematosalivarnyy bar'er v klinicheskoy praktike. Problemy stomatologii. 2021;2:62-67. [O.S. Chuykin, M.I. Shtanko, K.N. Kuchuk. Hematosalivary barrier in clinical practice. Actual problems in dentistry. 2021;2:62-67. (In Russ.)]. DOI: https://doi.org/10.18481/2077-7566-20-17-2-62-67.
8. Chuykin S.V., Akat'eva G.G., Makusheva N.V., Chuykin O.S., Egorova E.G., Kuchuk K.N., Bayburina E.K. Osobennosti stomatologicheskogo statusa detey s vrozhdennoy rasschelinoy guby i neba v regione s neftehimicheskimi ekotoksikantami. Problemy stomatologii. 2020;16(4):147-154. [S.V. Chuikin, G.G. Akat’eva, N.V. Makusheva, O.S. Chuikin, E.G. Egorova, K.N. Kuchuk, E.K. Baiburina. Features of the dental status of children with congenital cleft lip and palate in the region with petrochemical ecotoxicants. Actual problems in dentistry. 2020;16(4):147-154. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44667791
9. Chuykin O.S., Shtan'ko M.I., Kuchuk K.N. Gematosalivarnyy bar'er v klinicheskoy praktike. Problemy stomatologii. 2021;17(2):62-67. [O.S. Chuikin, M.I. Shtanko, K.N. Kuchuk. Hematosalivary barrier in clinical practice. Actual problems in dentistry. 2021;17(2):62-67. (In Russ.)]. https://www.elibrary.ru/item.asp?id=46411883
10. Kale S., Kakodkar P., Shetiya S., Abdulkader R. Prevalence of dental caries among children aged 5-15 years from 9 countries in the Eastern Mediterranean Region: a meta-analysis // East Mediterr Health J. - 2020;26(6):726-735. doi:https://doi.org/10.6719/emhj.20.050. PMID: 32621509.
11. Kazeminia M., Abdi A., Shohaimi S., Jalali R., Vaisi-Raygani A., Salari N., Mohammadi M. Dental caries in primary and permanent teeth in children's worldwide, 1995 to 2019: a systematic review and meta-analysis // Head Face Med. - 2020;6;16(1):22. doi:https://doi.org/10.1186/s13005-020-00237-z. PMID: 33023617; PMCID: PMC7541284.
12. Reyes L.T., Knorst J.K., Ortiz F.R., Mendes F.M., Ardenghi T.M. Pathways influencing dental caries increment among children: A cohort study // Int J Paediatr Dent. - 2021;31(3):422-432. doi:https://doi.org/10.1111/ipd.12730.
13. Schmoeckel J., Gorseta K., Splieth C.H., Juric H. How to Intervene in the Caries Process: Early Childhood Caries - A Systematic Review // Caries Res. - 2020;54(2):102-112. doi:https://doi.org/10.1159/000504335.
