Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
Ufa, Ufa, Russian Federation
GRNTI 76.29 Клиническая медицина
OKSO 31.05.03 Стоматология
BBK 566 Стоматология
Subject. The imposed restrictions on doctor visits caused by the pandemic Covid-19 and the severe course of the new coronavirus infection have changed the structure of dental care encounters. Objective of the study is to conduct a structural and quantitative analysis of dental care encounters of patients with the previous new coronavirus infection Covid-19. Methodology. A clinical and statistical patient chart was developed for this study. The initial encounters were analyzed in the period from March 2020 to December 2021. We have studied the frequency and structure of dental disease causes in patients who had recovered from the new coronavirus infection Covid-19 depending on the peaks of the Covid-19 incidence. In addition, the age and sex structure, the presence of concomitant diseases, and indicators of the oral cavity state were studied in the main group of patients: the decay-missing-filled index, mouth hygiene index, lesions of the oral mucosa, and regional lymph nodes reaction. The obtained data were processed with the statistical program Statistica 6.0, and differences in subgroups were analyzed according to the Student's t-test: the critical significance level was taken at p ≤ 0.05 when testing statistical hypotheses. Results. This study showed the dependence of the causes, frequency, and structure on pandemic periods. The predominance of the reasons for encounters changed in different periods of the pandemic. Besides, the age structure of patients changed in some periods of the pandemic. At the same time, no dependence of medical encounters on gender composition and comorbidities was observed. Conclusion. This study showed a high level of spread of the carious process. The level of the hygiene index was initially satisfactory, but also moved towards unsatisfactory. Enlargement of lymph nodes and the spread of lesions of the oral mucosa tended to increase during 2020–2021.
new coronavirus infection Covid-19, reasons for appeals, structural analysis, quantitative analysis, SARS-CoV-2 in the oral cavity
1. Vremennye Metodicheskie rekomendacii: profilaktika, diagnostika i lechenie novoy koronavivusnoy infekcii (COVID-19). Versiya 14, 27.12.2021-M. 2021:233. [Interim Guidelines: Prevention, Diagnosis and Treatment of Novel Coronavirus Infection (COVID-19). version 14, 27.12.2021 - M. 2021:233. (In Russ.)]. https://xn--80aesfpebagmfblc0a.xn--p1ai/ai/doc/1213/attach/vmr_COVID-19_V14_27-12-2021.pdf
2. Aydarov Z.A., Sabirova A.I., Mamytova A.B., Yusupov A.F. i dr. Organizacionno-metodicheskie aspekty stomatologicheskoy pomoschi v period pandemii novoy koronavirusnoy infekcii. The Scientific Heritage. 2020;50-2(50):11-17. [Z.A. Aidarov, A.I. Sabirova, A.B. Mamytova, A.F. Yusupov et al. Organizational and methodological aspects of dental care during the pandemic of a new coronavirus infection. The Scientific Heritage. 2020;50-2(50):11-17. (In Russ.)]. https://www.elibrary.ru/item.asp?id=43915146
3. Nikiforov V.V., Suranova T.G., Mironov A.Yu., Zabozlaev F.G. Novaya koronavirusnaya infekciya (COVID-19): etiologiya, epidemiologiya, klinika, diagnostika, lechenie i profilaktika. Moskva. 2020:48. [V.V. Nikiforov, T.G. Suranova, A. Yu. Mironov, F.G. Zabozlaev. New coronavirus infection (COVID-19): etiology, epidemiology, clinic, diagnosis, treatment and prevention. Mjscow. 2020:48. (In Russ.)]. https://www.epidbiomed-d.ru/professor/publikatsii/novaya-koronavirusnaya-infektsiya-covid-19-etiologiya-epidemiologiya-klinika-diagnostika-lechenie-i-/
4. Belocerkovskaya Yu.G., Romanovskih A.G., Smirnov I.P. COVID-19: Respiratornaya infekciya, vyzvannaya novym koronavirusom: novye dannye ob epidemiologii, klinicheskom techenii, vedenii pacientov. Consilium Medicum. 2020;3:12-20. [Yu.G. Belotserkovskaya, A.G. Romanovskikh, I.P. Smirnov. COVID-19: Respiratory infection caused by a new coronavirus: new data on epidemiology, clinical course, patient management. Consilium Medicum. 2020;3:12-20. (In Russ.)]. https://www.elibrary.ru/item.asp?id=42745698
5. Manak T.N., Matveev A.M., Luckaya I.K., Yudina N.A. Organizaciya stomatologicheskoy pomoschi pri koronavirusnyh infekciyah. Mezhdunarodnye obzory: klinicheskaya praktika i zdorov'e. 2020;2:20-31. [T.N. Manak, A.M. Matveev, I.K. Lutskaya, N.A. Yudina. Organization of dental care for coronavirus infections. International reviews: clinical practice and health. 2020;2:20-31. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44582993
6. Sorokina A.A., Losev F.F., Vagner V.D., Butova V.G. Zatraty rabochego vremeni vracha-stomatologa pri okazanii stomatologicheskoy pomoschi infekcionnym bol'nym. Klinicheskaya stomatologiya. 2021;1:156-159. [A.A. Sorokina, F.F. Losev, V.D. Wagner, V.G. Butova. The cost of working time of a dentist in the provision of dental care to infectious patients. Clinical dentistry. 2021;1:156-159. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44847644
7. Razumova S.N., Brago A.S., Kozlova Yu.S., Manvelyan A.S. i dr. Pandemiya Covid-19 i stomatologicheskaya praktika (obzor publikaciy). Medicinskiy alfavit. 2020;12:58-61. [S.N. Razumova, A.S. Brago, Yu.S. Kozlova, A.S. Manvelyan et al. Covid-19 pandemic and dental practice (review of publications). Medical alphabet. 2020;12:58-61. (In Russ.)]. https://stopkoronavirus.rf//.https://stopcoronavirus.rf/
8. Sun K., Viboud C. Impact of contact tracing on SARS-CoV-2 transmission // Lancet Infect Dis. - 2020 Aug;20(8):876-877. doi:https://doi.org/10.1016/S1473-3099(20)30357-1.
9. Kucharski A.J., Russell T.W., Diamond C., Yang Liu C. et al. Early dynamics of transmission and control COVID-19: a study with mathematical modeling // Lancelet infect. Dis. - 2020;20(5):553-558. doi:https://doi.org/10.1016/S1473-3099(20)30144-4.
10. Modina T.N., Cinekker D.T., Haritonova M.A., Mahdi M.M.M. Sars-cov-2 v polosti rta i obostrenie hronicheskoy parodontal'noy patologii u pacientov s novoy koronavirusnoy infekciey (COVID-19). Problemy stomatologii. 2021;1:70-75. [T.N. Modina, D.T. Zinecker, M.A. Kharitonova, M.M.M. Mahdi. Sars-cov-2 in the oral cavity and exacerbation of chronic periodontal disease in patients with novel coronavirus infection (COVID-19). Actual problems in Dentistry. 2021;1:70-75. (In Russ.)]. https://www.elibrary.ru/item.asp?id=45699798
11. Nasibullina A.H., Kabirova M.F., Kabirov I.R., Valishin D.H. Osobennosti stomatologicheskogo statusa pacientov s SARS-COV-2. Problemy stomatologii. 2021;17(3):29-34. [ A.Kh. Nasibullina, M.F. Kabirova, I.R. Kabirov, D.Kh. Valishin. Features of the dental status of patients with SARS-COV-2. Actual problems in Dentistry. 2021;17(3):29-34. (In Russ.)]. https://www.elibrary.ru/item.asp?id=47176552
12. Aydarov Z.A., Sabirova A.I., Sabirov I.S., Mamytova A.B. Novaya koronavirusnaya infekciya (COVID-19) i saharnyy diabet: vzglyad stomatologa. The Scientific Heritage. 2021;58-2(58):44-51. [Z.A. Aidarov, A.I. Sabirova, I.S. Sabirov, A.B. Mamytova. New coronavirus infection (COVID-19) and diabetes mellitus: a dentist's view. The Scientific Heritage. 2021;58-2(58):44-51. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44577644
13. Vardanyan M.G., Pashkova G.S., Popov A.A. Sostoyanie polosti rta pri COVID-19. Sbornik statey III Nauchno-prakticheskoy konferencii Mediko-biologicheskogo universiteta innovaciy i nepreryvnogo obrazovaniya «Nauchnyy avangard» i Mezhvuzovskoy olimpiady ordinatorov i aspirantov, posvyaschennyh 75-letiyu FGBU GNC FMBC im. A.I. Burnazyana FMBA Rossii. M.: FGBU GNC FMBC im. A.I. Burnazyana FMBA Rossii. 2021:178-183. [M.G. Vardanyan, G.S. Pashkova, A.A. Popov. The state of the oral cavity with COVID-19. Collection of articles of the III Scientific and Practical Conference of the Biomedical University of Innovation and Lifelong Education "Scientific Avant-Garde" and the Interuniversity Olympiad of Residents and Postgraduate Students A.I. Burnazyan FMBA of Russia. M.: FGBU GNTs FMBTs im. A.I. Burnazyan FMBA of Russia. 2021:178-183. (In Russ.)].
14. Makedonova Yu.A., Poroyskiy S.V., Gavrikova L.M., Afanas'eva O.Yu. Proyavlenie zabolevaniy slizistoy polosti rta u bol'nyh, perenesshih Covid-19. Vestnik VolgGMU. 2021;1(77):110-115. [Yu.A. Makedonova, S.V. Poroisky, L.M. Gavrikova, O.Yu. Afanasyev. Manifestation of diseases of the oral mucosa in patients with Covid-19. Bulletin of the VolgGMU. 2021;1(77):110-115. (In Russ.)]. https://www.elibrary.ru/item.asp?id=45153499
15. Nasibullina A.H., Valishin D.H. Osobennosti mikrobnogo sostava zubnogo naleta u pacientov s podtverzhdennym diagnozom SARS-COV-2. Problemy stomatologii. 2021;17(4):56-61. [A.Kh. Nasibullina, D.Kh. Valishin. Features of the microbial composition of dental plaque in patients with a confirmed diagnosis of SARS-COV-2. Actual problems in Dentistry. 2021;17(4):56-61. (In Russ.)]. https://www.elibrary.ru/item.asp?id=47871055
16. Habadze Z.S., Sobolev K.E., Todua I.M., Mordanov O.S. Izmeneniya slizistoy obolochki polosti rta i obschih pokazateley pri Covid-19 (SARS-CoV-2):odnocentrovoe opisatel'noe issledovanie. Endodontiya Today. 2020;18(2):4-9. [Z.S. Khabadze, K.E. Sobolev, I.M. Todua, O.S. Mordanov. Changes in the oral mucosa and general indicators in Covid-19 (SARS-CoV-2): a single-center descriptive study. Endodontics Today. 2020;18(2):4-9. (In Russ.)]. https://www.elibrary.ru/item.asp?id=43326778
17. Rahmati M., Moosavi M.A. Cytokine-targeted therapy in severely ill COVID-19 patients: Options and cautions // EJMO. - 2020;4(2):179-181. https://doi.org/10.14744/ejmo.2020.72142.
18. Moore John B., June Carl H. Cytokine release syndrome in severe COVID-19 // Science. - 2020;368(6490):473-474. https://doi.org/10.1126/science.abb8925.
19. Badran Z., Gaudin A., Struillou X., Amador G. et al. Periodontal pockets: A potential reservoir for SARS-CoV-2 // Med Hypotheses. - 2020;143:109907. https://doi.org/10.1016/j.mehy.2020.109907
20. Turner A.J., Hiscox J.A., Hooper N.M. ACE2: from vasopeptidase to SARS virus receptor. Trends in Pharmacological Sciences journal // Cell Press. - 2004;25(6):291-294. https://doi.org/10.1016/j.tips.2004.04.001.
21. Hui D.S., Azhar E., Madani T.A., Ntoumi F. et al. The continuing 2019nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China // Int J Infect Dis.Feb. - 2020;91:264-266. https://doi.org/10.1016/j.ijid.2020.01.009.
22. Wong H.S., Germain R.N. Robust control of the adaptive immune system // PMID. - 29290544. https://doi.org/10.1016/j.smim.2017.12.009.
23. Chi Zhang, Zhao Wu, Jia-Wen Li, Hong Zhao et al. Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality // Int J Antimicrob Agents. - 2020;55(5):105954. https://doi.org/10.1016/j.ijantimicag.2020.105954.
24. Matthew Z.T., Chek M.P., Laurent R., MacAry P.A. et al. Tne trinity of COVID-19: immunity, inflammation and intervention // Nat Rev Immunol. - 2020;20(6):363-374. https://doi.org/10.1038/s41577-020-0311-8.
