FEATURES OF CLINICAL MANIFESTATIONS OF MAJOR DENTAL DISEASES IN PATIENTS WITH TYPE 2 DIABETES MELLITUS (LITERATURE REVIEW)
Abstract and keywords
Abstract (English):
Subject. The article is a literary review devoted to the peculiarities of clinical manifestations of major dental diseases in patients with impaired carbohydrate metabolism, type 2 diabetes mellitus. Methodology. The data of Russian and foreign literature were studied using scientific search library databases: PubMed, Elibrary, Cochrane. Literature analysis was carried out on 59 sources over the past 5 years (42 domestic authors and 17 foreign ones). The analysis of the literature data allows us to consider type 2 diabetes mellitus as highly common somatic diseases leading to the development of various symptoms, syndromes and diseases of the hard tissues of the teeth, periodontal and oral mucosa. Results. Among the wide range of possible complications and symptoms are - impaired taste sensitivity, the presence of xerostomia, burning mouth syndrome, glossalgia, lichen planus, leukoplakia, candidiasis, chronic inflammatory diseases of periodontal tissues, complicated and uncomplicated caries of hard dental tissues. Diagnostic and therapeutic and preventive measures in this case should be aimed at their early diagnosis and prevention. Conclusions. Against the background of manifestations of DM2, there is a significant prevalence of major dental diseases, which most often depends not only on the duration of the course and severity of DM2, but also on the state of carbohydrate metabolism compensation, age and gender. Undoubtedly, the principle of continuity of interested specialties, including dentists, endocrinologists, gastroenterologists and other specialists, has great prospects both in the diagnosis and prevention of pathology of the oral mucosa.

Keywords:
carbohydrate metabolism disorder, type 2 diabetes mellitus, glycated hemoglobin, periodontal disease, caries, burning, pain, candidiasis, lichen planus, glossalgia, burning mouth syndrome
References

1. Borisova E.G., Komova A.A., Nikitina E.A., Pendyurina M.K. Ocenka kachestva zhizni u pacientov s bolevymi i paresteticheskimi simptomami slizistoy obolochki polosti rta. Zdorov'e i obrazovanie v XXI veke. 2018;9(20):57-61. [Je.G. Borisova, A.A. Komova, E.A. Nikitina, M.K. Pendjurina. Assessment of the quality of life in patients with pain and paresthetic symptoms of the oral mucosa. Health and Education in the 21st Century. 2018;9(20):57-61. (In Russ.)]. https://elibrary.ru/item.asp?id=35727367

2. Budina D.O., Obzherina V.O., Chicherina E.N., Nikitina E.A. Cvyaz' zabolevaniy slizistoy obolochki polosti rta i saharnogo diabeta 2 tipa. Profilaktika patologiy SOPR. E-Scio. 2021;6:128-137. [D.O. Budina, V.O. Obzherina, E.N. Chicherina, E.A. Nikitina. The relationship of diseases of the oral mucosa and type 2 diabetes mellitus. Prevention of pathologies of SOPR. E-Scio. 2021;6:128-137. (In Russ.)]. https://elibrary.ru/item.asp?id=46363159

3. Petruhina N.B., Zorina O.A., Abaev Z.M. i dr. Vliyanie gendernyh, vozrastnyh i metabolicheskih faktorov na techenie hronicheskogo generalizovannogo parodontita u pacientov s metabolicheskim sindromom. Stomatologiya. 2019;98;2:31-36. [N.B. Petrukhina, O.A. Zorina, Z.M. Abaev et al. Influence of gender, age and metabolic factors on the course of chronic generalized periodontitis in patients with metabolic syndrome. Dentistry. 2019;98;2:31-36. (In Russ.)]. https://doi.org/10.17116/stomat20199802131

4. Verbovoy A.F., Sharonova L.A., Burakshaev S.A. i dr. Vozmozhnosti profilaktiki izmeneniy kozhi i slizistoy obolochki rta pri saharnom diabete na sovremennom etape. Farmateka. 2017;16(349):62-65. [A.F. Verbovoy, L.A. Sharonova, S.A. Burakshayev et al. Opportunities for prevention of changes in skin and oral mucosa in diabetes mellitus at the present stage. Pharmateka. 2017;16(349):62-65. (In Russ.)]. https://elibrary.ru/item.asp?id=30520039

5. Uspenskaya O.A, Kachesova E.S. Izmeneniya biohimicheskih pokazateley krovi pri lechenii bystroprogressiruyuschego parodontita. Problemy stomatologii. 2017;13(2):33-38. [O.A. Uspenskaya, E.S. Kachesova. Changes in blood chemistry values in the course of treatment of the rapidly progressive periodontitis. Actual problems in dentistry. 2017;13(2):33-38. (In Russ.)]. https://doi.org/10.18481/2077-7566-2017-13-2-33-38

6. Verbovoy A.F., Sharonova L.A., Burakshaev S.A., Kotel'nikova E.V. Izmeneniya kozhi i slizistoy polosti rta pri saharnom diabete i ih profilaktika. Medicinskiy sovet. 2017;3:54-57. [A.F. Verebovoy, L.A. Sharonova, S.A. Burakshaev, E.V. Kotelnikova. Changes of skin and oral mucosa in diabetes mellitus and their prevention. Medical Advice. 2017;3:54-57. (In Russ.)]. https://doi.org/10.21518/2079-701X-2017-3-54-57

7. Iordanishvili A.K., Soldatova L.N., Soldatov S.V., Zuykova M.A., Soldatov V.S. Harakteristika sostoyaniya tkaney parodonta i gigieny polosti rta u lic starshego vozrasta pri komorbidnoy patologii i puti ee uluchsheniya. Parodontologiya. 2018;24(4):4-8.[A.K. Iordanishvili, L.N. Soldatova, S.V. Soldatov, M.A. Zuykova, V.S. Soldatov. The characteristic of a condition of parodentium tissues and oral hygiene at the elder people with comorbid pathology and the ways of its improvement. Periodontology. 2018;24(4):4-8. (In Russ.)]. https://doi.org/10.25636/PMP.1.2018.4.1

8. Katola V.M., Tarasenko S.V., Komogorceva V.E. Vliyaniya mikrobioty polosti rta na razvitie vospaleniya i somaticheskih zabolevaniy. Rossiyskiy stomatologicheskiy zhurnal. 2018;22;3:162-165. [V.M. Katola, S.V. Tarasenko, V.E. Komogortseva. Effect of oral microbiota on the development of inflammation and somatic diseases. Russian Dental Journal. 2018;22;3:162-165. (In Russ.)]. https://doi.org/10.18821/1728-2802-2018-22-3-162-165

9. Svechnikova E.V., Lykova S.G., Nemchaninova O.B., Morzhanaeva M.A. Klinicheskie osobennosti porazheniya kozhi u pacientov s saharnym diabetom. Farmateka. 2020;27(12):20-25. [E.V. Svechnikova, S.G. Lykova, O.B. Nemchaninova, M.A. Morzhanaeva. Clinical features of skin lesions in patients with diabetes mellitus. Pharmateka. 2020;27(12):20-25. (In Russ.)]. https://doi.org/10.18565/pharmateca.2020.12.20-25.

10. Zakar'yaev A.Z., Shihnebiev D.A., Medzhidov M.N., Shihnabieva E.D. Komorbidnost' bolezney parodonta i vnutrennih organov. Vestnik Dagestanskoy gosudarstvennoy medicinskoy akademii. 2018;1;26:78-83. [A.Z. Zakaryaev, D.A. Shiknebiev, M.N. Medzhidov, E.D. Shiknabieva. Comorbidity of periodontal diseases and internal organs. Bulletin of the dagestan state medical academy. 2018;1;26:78-83. (In Russ.)]. https://elibrary.ru/item.asp?id=32683806

11. Kopeckiy I.S., Pobozh'eva L.V., Shevelyuk Yu.V. Vzaimosvyaz' vospalitel'nyh zabolevaniy parodonta i obschesomaticheskih zabolevaniy. Lechebnoe delo. 2019;2:7-12. [I.S. Kopetskiy, L.V. Pobozhieva, Yu.V. Sheveluk. Correlation between periodontitis and systemic diseases. Medical Business. 2019;2:7-12. (In Russ.)]. https://doi.org/10.24411/2071-5315-2019-12106

12. Kostrigina E.D., Zyul'kina L.A., Ivanov P.V. Sovremennyy vzglyad na etiopatogenez parodontita (obzor literatury). Izvestiya vysshih uchebnyh zavedeniy. Povolzhskiy region. 2017;3:118-128. [E.D. Kostrigina, L.A. Zyul'kina, P.V. Ivanov. A modern view of the etiopathogenesis of periodontitis (a review of literature). University proceedings. Volga region. Medical sciences. 2017;3:118-128. (In Russ.)]. https://doi.org/10.21685/2072-3032-2017-3-13

13. Mel'nichenko D.I., Romanenko I.G. Vzaimosvyaz' zabolevaniy tkaney parodonta i porazheniy podzheludochnoy zhelezy. Krymskiy terapevticheskiy zhurnal. 2017;23-26. [D.I. Melnychenko, I.G. Romanenko. The correlation between parodontal diseases and pacreatitis. Crimean journal of internal diseases. 2017;23-26. (In Russ.)]. https://elibrary.ru/item.asp?id=30068128

14. Moroz P.V., Iordanishvili A.K. Faktory riska vozniknoveniya i prichiny nizkoy effektivnosti lecheniya endodontoparodontal'nyh porazheniy. Endodontiya today. 2018;1:35-41. [P.V. Moroz, A.K. Iordanishvili. Risk factors for the occurrence and causes of low effectiveness of treatment of endodontoperiodontal lesions. Endodontiya today. 2018;1:35-41. (In Russ.)]. https://doi.org/10.25636/PMP.2.2018.1.6

15. Zharkova I.V. Optimizaciya diagnostiki i lecheniya hronicheskih mehanicheskih travm slizistoy obolochki rta u pacientov s saharnym diabetom 1 tipa : diss. … kandidata medicinskih nauk [FGBOU VO Bashkirskiy gosudarstvennyy medicinskiy universitet]. Ufa, 2019:141. [I.V. Zharkova. Optimization of diagnosis and treatment of chronic mechanical injuries of the oral mucosa in patients with type 1 diabetes mellitus : diss. ... Candidate of Medical Sciences. Bashkir State Medical University. Ufa, 2019:141. (In Russ.)]. https://elibrary.ru/item.asp?id=ID:41521368

16. Orehova L.Yu., Loboda E.S., Grinenko E.V., Musaeva R.S. Effektivnost' kompleksnoy konservativnoy parodontal'noy terapii s primenenii schadyaschey metodiki obrabotki ul'trazvukovym apparatom s poliruyuschey suspenziey na osnove gidrookisi kal'ciya u pacientov s saharnym diabetom 1 tipa i hronicheskim generalizovannym parodontitom. Parodontologiya. 2019;24(3):223-231. [L.Yu. Orekhova, E.S. Loboda, E.V. Grinenko, R.S. Musaeva. The effectiveness of complex conservative periodontal therapy using a gentle treatment technique by ultrasonic apparatus with calcium hydroxide polishing suspension among patients with type 1 diabetes and chronic generalized periodontitis. Periodontology. 2019;24(3):223-231. (In Russ.)]. https://doi.org/10.33925/1683-3759-2019-24-3-223-231.

17. Orehova L.Yu., Musaeva R.S., Loboda E.S., Grinenko E.V., Chuprinina A.V., Ryazanceva E.S. Analiz effektivnosti protivovospalitel'nyh past u pacientov s saharnym diabetom i hronicheskim generalizovannym parodontitom. Parodontologiya. 2020;25(1):47-53. [L.Yu. Orekhova, R.S. Musaeva, E.S. Loboda, E.V. Grinenko, A.V. Chuprinina, E.S. Ryazantseva. Analysis of anti-inflammatory toothpastes efficiency among patients with diabetes mellitus and chronic generalized periodontitis. Periodontology. 2020;25(1):47-53. (in Russ.)]. https://doi.org/10.33925/1683-3759-2020-25-1-47-53

18. Gileva O.S., Smirnova E.N., Pozdnyakova A.A., Libik T.V. Osobennosti diagnostiki i lecheniya kserostomicheskogo sindroma pri zabolevaniyah parodonta i slizistoy obolochki polosti rta u pacientov s saharnym diabetom 2-go tipa. RMZh. 2016;24(20):1340-1345. [O.S. Gileva, E.N. Smirnova, A.A. Pozdnyakova, T.V. Libik. Hallmarks of diagnosis and treatment of xerostomia syndrome in patients with periodontal and oral mucosal diseases and diabetes mellitus type 2. RMJ. 2016;24(20):1340-1345. (In Russ.)]. https://elibrary.ru/item.asp?id=28124434

19. Moroz P.V., Iordanishvili A.K., Prohodnaya V.A. i dr. Osobennosti klinicheskogo techeniya i principy lecheniya endodonto-parodontal'nyh porazheniy. Kazanskiy medicinskiy zhurnal. 2018;3(99):362-368. [P.V. Moroz, A.K. Iordanishvili, V.A. Prokhodnaya et al. Features of the clinical course and principles of treatment of endodonto periodontal lesions. Kazan Medical Journal. 2018;3(99):362-368. (In Russ.)]. https://doi.org/10.17816/KMJ2018362

20. Aramisova R.M., Thazaplizheva M.T., Kardanova S.Yu., Baksanokova D.A., Sabanchieva H.A., Chochaeva M.Zh., Kerefova Z.V. Osobennosti stomatologicheskogo statusa u bol'nyh saharnym diabetom. Sovremennaya nauka: aktual'nye problemy teorii i praktiki. Seriya: Estestvennye i tehnicheskie nauki. 2020;1:151-156. [R.M. Aramisova, M.T. Thazaplizheva, S.Yu. Kardanova, D.A. Baksanokova, H.A. Sabanchieva, M.Z. Chochaeva, Z.V. Kerefova. Features of dental status in patients with diabetes mellitus. Modern science: actual problems of theory and practice. Series: natural and technical sciences. 2020;1:151-156. (In Russ.)]. https://elibrary.ru/item.asp?id=42632341

21. Gileva O.S., Koshkin S.V., Libik T.V. i dr. Parodontologicheskie aspekty zabolevaniy slizistoy obolochki polosti rta: krasnyy ploskiy lishay. Parodontologiya. 2017;22;3(84):9-14. [O.S. Gileva, S.V. Koshkin, T.V. Libik et al. Periodontological aspects of diseases of the oral mucosa: lichen planus. Periodontology. 2017;22;3(84):9-14. (In Russ.)]. https://elibrary.ru/item.asp?id=30060549

22. Petrova T.G., Borodina N.B., Rymar S.D., Rymar O.D. Vzaimodeystvie stomatologa s endokrinologom - komandnyy podhod v lechenii vospalitel'nyh zabolevaniy parodonta u pacientov s saharnym diabetom 2-go tipa (obzor literatury). Parodontologiya. 2019;24(2):140-144. [T.G. Petrova, N.B. Borodina, S.D. Rymar, O.D. Rymar. The interaction of the dentist with an endocrinologist - a team approach in the treatment of inflammatory periodontal diseases in patients with type 2 diabetes mellitus (literature review). Periodontology. 2019;24(2):140-144. (In Russ.)]. https://doi.org/10.33925/1683-3759-2019-24-2-140-144

23. Yanushevich O.O., Duhovskaya N.E., Vavilova T.P., Ostrovskaya I.G., Evarnickaya N.R. Pokazateli smeshannoy slyuny u lic s somaticheskoy patologiey. Dental Forum. 2019;1(72):27-36. [O.O. Yanushevich, N.E. Dukhovskaya, T.P. Vavilova, I.G. Ostrovskaya, N.R. Evarnitskaya. Saliva indices in patients with somatic pathology. Dental Forum. 2019;1(72):27-36. (In Russ.)]. https://elibrary.ru/item.asp?id=37307576

24. Prisyazhnyuk O.V., Iordanishvili A.K., Muzykin M.I. Stomatologicheskaya reabilitaciya pri zabolevaniyah parodonta i slizistoy obolochki polosti rta na fone saharnogo diabeta 2 tipa. Parodontologiya. 2020;25;1:27-31. [O.V. Prisyazhnyuk, A.K. Iordanishvili, M.I. Muzikin. Dental rehabilitation for periodontal and oral mucosa diseases in type 2 diabetes. Periodontology. 2020;25(1):27-31. (In Russ.)]. https://doi.org/10.33925/1683-3759-2020-25-1-27-31

25. Petruhina N.B., Zorina O.A., Shih E.V. i dr. Prognosticheskaya model' dlya ocenki hronicheskogo generalizovannogo parodontita u pacientov s metabolicheskim sindromom. Vestnik Rossiyskogo gosudarstvennogo medicinskogo universiteta. 2019;2:48-52. [N.B. Petrukhina, O.A. Zorina, E.V. Shikh, E.V. Kartysheva, A.V. Kudryavtsev. A prognostic model for the prediction of generalized chronic periodontitis in patients with metabolic syndrome. Bulletin of Russian State Medical University. 2019;2:48-52. (In Russ.)]. https://doi.org/10.24075/vrgmu.2019.026

26. Redinova T.L., Zlobina O.A., Dmitrakova N.R., Timofeeva V.N., Tarasova Yu.G. Rasprostranennost' zabolevaniy slizistoy obolochki polosti rta v razlichnyh regionah Udmurtskoy respubliki i ih struktura. Vyatskiy medicinskiy vestnik. 2019;2(62):69-72. [T.L. Redinova, O.A. Zlobina, N.R. Dmitrakova, V.N. Timofeeva, U.G. Tarasova. Prevalence of oral mucosa diseases in various regions of the udmurtrepublic and their structure. Medical newsletter of Vyatka. 2019;2(62):69-72. (In Russ.)]. https://elibrary.ru/item.asp?id=38213972

27. Efanova E.N., Rusak Yu.E., Vasil'eva E.A., Nelidova N.V. Sluchay sochetaniya krasnogo ploskogo lishaya, universal'nogo vitiligo i patologii zheludochno-kishechnogo trakta. Lechaschiy vrach. 2019;2:74-76. [E.N. Efanova, Yu.E. Rusak, E.A. Vasilieva, N.V. Nelidova. A case of combination of lichen planus, universal vitiligo and pathology of gastrointestinal tract. Lechaschi Vrach. 2019;(2):74. (In Russ.)]. https://elibrary.ru/item.asp?id=37070807

28. Kostrigina E.D., Zyul'kina L.A., Ivanov P.V. Sovremennyy vzglyad na etiopatogenez parodontita (obzor literatury). Izvestiya vysshih uchebnyh zavedeniy. Povolzhskiy region. Medicinskie nauki. 2017;3;43:118-128. [E.D. Kostrigina, L.A. Zyul'kina, P.V. Ivanov. A modern view of the etiopathogenesis of periodontitis (a review of literature). Volga region. Medical sciences. 2017;3;43:118-128. (In Russ.)]. https://doi.org/10.21685/2072-3032-2017-3-13

29. Petrova T.G., Moreva N.A., Rymar S.D. i dr. Sostoyanie polosti rta u pacientov s saharnym diabetom tipa MODY. Journal of Siberian Medical Sciences. 2019;3:74-83. [T.G. Petrova, N.A. Moreva, S.D. Rymar. He condition of the oral cavity in patients with mody type diabetes mellitus. Journal of Siberian Medical Sciences. 2019;3:74-83. (In Russ.)]. https://doi.org/10.31549/2542-1174-2019-3-74-83.

30. Stepanova T.V., Ivanov A.N., Popyhova E.B., Lagutina D.D. Molekulyarnye markery endotelial'noy disfunkcii. Sovremennye problemy nauki i obrazovaniya. 2019;1:37. [T.V. Stepanova, A.N. Ivanov, E.B. Popykhova, D.D. Lagutina. Moleculare markers of the endothelial dysfunction. Modern problems of science and education. 2019;1:37. (In Russ.)]. https://elibrary.ru/item.asp?id=37031896

31. Titarenko M.A., Stolyarova V.A., Sysolyatin P.G., Baydik O.D. Osobennosti klinicheskogo techeniya krasnogo ploskogo lishaya slizistoy obolochki polosti rta u bol'nyh s narusheniyami uglevodnogo obmena. Klinicheskaya dermatologiya i venerologiya. 2018;17(4):58-64. [M.A. Titarenko, V.A. Stoliarova, P.G. Sysolyatin, O.D. Baydik. Characteristic features of the clinical course of the lichen ruber planus of the oral mucosa in patientswith impaired carbohydrate metabolism. Clinical dermatology and venereology. 2018;17(4):58-64. (In Russ.)]. https://doi.org/10.17116/klinderma20181704158

32. Titarenko M.A., Baydik O.D., Sysolyatin P.G. Rol' oksida azota (II) i ego aktivnyh metabolitov v kancerogeneze slizistoy obolochki polosti rta. Rossiyskiy stomatologicheskiy zhurnal. 2016;20(3):165-168. [O.D. Baydik, M.A. Titarenko, P.G. Sysolyatin. Role nitrogen oxide and reactive nitrogen species in cancerogenesis of oral mucous membrane. Russian Dental Journal. 2016;20(2):159-164. (In Russ.)]. https://doi.org/10.18821/1728-2802 2016

33. Titarenko M.A., Stolyarova V.A., Sysolyatin P.G., Baydik O.D. Rol' gastrointestinal'noy patologii v razvitii i tyazhesti techeniya krasnogo ploskogo lishaya slizistoy obolochki polosti rta. Byulleten' sibirskoy mediciny. 2018;17(3):151-156. [M.A. Titarenko, V.A. Stolyarova, P.G. Sysolyatin, O.D. Baydik. The role of gastrointestinal pathology in the development and severity of oral lichen planus. Bulletin of siberian medicine. 2018;17(3):151-156. (In Russ.)]. https://doi.org/10.20538/1682-0363-2018-3-151-156

34. Uspenskaya O.A., Kachesova E.S. Rol' obschih i mestnyh faktorov v vozniknovenii i razvitii hronicheskogo generalizovannogo parodontita tyazheloy stepeni. Sovremennye problemy nauki i obrazovaniya. 2017;(5):188. [O.A. Uspenskaya, E.S. Kachesova. The role of general and local factors in the occurrence and development of chronic generalized severe periodontitis. Modern problems of science and education. 2017;(5):188. (In Russ.)]. https://elibrary.ru/item.asp?id=30457991

35. Fazylova Yu.V., Fatihova R.R., Blashkova S.L. Sovremennye principy lecheniya proyavleniy krasnogo ploskogo lishaya na slizistoy obolochke rta. Molodoy uchenyy. 2018;24(210):289-293. [Yu.V. Fazylova, R.R. Fatikhova, S.L. Blashkova. Modern principles of treatment of manifestations of lichen planus on the oral mucosa. Young scientist. 2018;24(210):289-293. (In Russ.)]. https://elibrary.ru/item.asp?id=35127699

36. Hromova E.A., Kulik I.V., Udal'cova N.A., Iordanishvili A.K. Osobennost' mestnyh lechebno-profilakticheskih meropriyatiy v lechenii parodontita u pacientov s saharnym diabetom 2 tipa. Parodontologiya. 2018;24(4):67-70. [E.A. Khromova, I.V. Kulik, N.A. Udaltsova, A.K. Iordanishvili. Peculiarity of local treatment-preventive activities in the treatment of parodontitis in patients with diabetes type 2. Periodontology. 2018;24(4):67-70. (In Russ.)]. https://doi.org/10.25636/PMP.1.2018.4.12

37. Cepov L.M., Nikolaev A.I., Nesterova M.M., Cepova E.L., Cepov A.L. Mnozhestvennye hronicheskie sistemnye zabolevaniya i patologiya parodonta. Parodontologiya. 2019;24(2):127-131. [L.M. Tsepov, A.I. Nikolaev, M.M. Nesterova, E.L. Tsepova, A.L. Tsepov. Multiple chronic system diseases and periodontal pathology. Periodontology. 2019;24(2):127-131. (In Russ.)]. https://doi.org/10.33925/1683-3759-2019-24-2-127-131

38. Shevchenko E.A., Uspenskaya O.A., Zagrebin E.A., Spiridonova S.A. Narushenie gemostaza kak prichina parodontita u bol'nyh saharnym diabetom II tipa. Parodontologiya. 2021;26(3):240-244. [E.A. Shevchenko, O.A. Uspenskaya, E.A. Zagrebin, S.A. Spiridonova. Hemostasis disorder as a cause of periodontitis in type II diabetic patients. Periodontology. 2021;26(3):240-244. (In Russ.)]. https://doi.org/10.33925/1683-3759-2021-26-3-240-244

39. Shihnabieva E.D., Shihnebiev D.A. Komorbidnost' vospalitel'nyh zabolevaniy tkaney parodonta i vnutrenney sistemy (obzor literatury). Cathedra. Stomatologicheskoe obrazovanie. 2020;71:36-39. [E. Shiknabieva, D. Shiknebiev. Comorbidity of inflammatory diseases of periodontal tissues and the internal system (literature review). Cathedra. Dental education. 2020;71:36-39. (In Russ.)]. https://elibrary.ru/item.asp?id=42926525

40. Yan Boven', Chikunov S.O, Li Czyaci. Prognosticheskoe znachenie morfologicheskih izmeneniy v pereimplantatnyh tkanyah pri giperglikemii razlichnoy etiologii. Institut stomatologii. 2019;4(85):118-119. [Boven' Yan, S.O. Chikunov, Li Czyaci. Prognostic value of morphological changes in peri-implant tissues with hyperglycemia of various etiology The dental institute. 2019;4(85):118-119. (In Russ.)]. https://elibrary.ru/item.asp?id=41717323

41. Yan Boven', Chikunov S.O., Li Czyaci. Osobennosti morfologicheskih izmeneniy v pereimplantatnyh tkanyah pri giperglikemii razlichnoy etiologii. Klinicheskaya stomatologiya. 2019;3(91):56-58. [Boven' Yan, S.O. Chikunov, Li Czyaci. Peculiarities of morphological changes in periimplantary tissues by hyperglycemia various etiologies. Clinical Dentistry. 2019;3(91):56-58. (In Russ.)]. https://doi.org/10.37988/1811-153X_2019_3_56

42. Gomaa M.A., Guindy H.M., Mahmoud M.A. et al. Adjunctive sub antimicrobial dose doxycycline in the treatment of chronic periodontitis in type 2 diabetic patients: a unique combination therapy // Balk. J. Dent. Med. - 2018;22(1):32-37. https://doi.org/10.2478/bjdm-2018-0006

43. Buti F.Q., Almeida-da-Silva C.L., Huynh B. et al. Association between periodontal pathogens and systemic disease // Biomedical journal. - 2019;42:27-35. https://doi.org/10.1016/j.bj.2018.12.001

44. Hayashi J. et al. Effects of periodontal treatment on the medical status of patients with type 2 diabetes mellitus: a pilot study // BMC Oral Health. - 2017:654-660. https://doi.org/10.1186/s12903-017-0369-2

45. Ronaldo Lira Junior et al. Effects on HbA1c in diabetic patients of adjunctive use of systemic antibiotics in nonsurgical periodontal treatment: A systematic review // Journal of Dentistry. - 2017;66:1-7. https://doi.org/10.1016/j.jdent.2017.08.001

46. Latti B.R., Kalburge J.V., Birajdar S.B. et al. Evaluation of relationship between dental caries, diabetes mellitus and oral microbiota in diabetics // J. of oral and maxillofacial pathology. - 2018;2;22:282. https://doi.org/10.4103/jomfp.JOMFP_163_16

47. Benrachadi L., Saleh Z.M., Bouziane A. L’impact de la thérapeutique parodontale sur l’équilibre de diabète: revue systématique // The impact of periodontal therapy on the diabetes control: A systematic review. - 2019;48(1):4-18. https://doi.org/10.1016/j.lpm.2018.12.002

48. Madianos P.N., Koromantzos P.A. An update of the evidence on the potential impact of periodontal therapy on diabetes outcomes // J. of Clin. Periodontol. - 2018;5(2):188-195. https://doi.org/10.1111/jcpe.12836. Epub 2017 Dec 26

49. Muhammad A.N. Prevalence of periodontal disease, its association with systemic diseases and prevention // Int. J. of health sciences. - 2017;1:72-80. PMCID: PMC5426403

50. Nazir M.A. Prevalence of periodontal disease, its association with systemic diseases and prevention // Int. J. Health Sci. (Qassim). - 2017;11(2):72-80. https://doi.org/10.1155/2018/6924631

51. Orekhova L.Yu., Musaeva R.S., Silina E.S., Aleksandrova A.A., Grinenko E.V., Loboda E.S. Features of hard tooth and periodontal tissues among women with diabetes mellitus in various trimesters of pregnancy // Periodontology. - 2019;24(1):29-33. (In Russ.). https://doi.org/10.25636/PMP.1.2019.1.5

52. Chang J.F., Yet J.C., Chiu Y. L. et al. Periodontal Pocket Depth, Hyperglycemia, and Progression of Chronic Kidney Disease: A Population-Based Longitudinal Study // The Amer. J. of Med. - 2017;130(1):61-69. https://doi.org/10.1016/j.amjmed.2016.08.024

53. Teeuw W.J., Kosho M.X.F., DPoland C.W. et al. Periodontitis as a possible early sign of diabetes mellitus // BMJ Open diabetes Research & Care. - 2017;5(1):7. https://doi.org/10.1136/bmjdrc-2016-000326

54. Polak D., Shapira L. An update of the evidence for pathogenic mechanisms that may link periodontitis and diabetes // J. of Clin. Periodontol. - 2018;45(2):150-166. https://doi.org/10.1111/jcpe.12803

55. Sanz M., Ceriello A., Buysschaert M. et al. Scientific evidence on the links between periodontal diseases and diabetes: Consensus report and guidelines of the joint workshop on periodontal diseases and diabetes by the International iabetes Federation nd the European Federation of Periodontology // Journal of clinical Periodontology. - 2018;45(2):138-149. https://doi.org/10.1111/jcpe.12808

56. Sanz M., Ceriello A., Buysschaert M. et al. Scientific evidence on the links between periodontal disease and diabetes: Consensus report and guidelines of the joint workshop on periodontal disease and diabetes by the International diabetes Federation and the European Federation of Periodontology // Diabetes Res. and Clin. Pract. - 2018;137:231-241. https://doi.org/doi:https://doi.org/10.1016/j.diabres.2017.12.001

57. Bazyar H., Maghsoumi-Norouzabad L., Yarahmadi M. et al. The Impacts of Synbiotic Supplementation on Periodontal Indices and Biomarkers of Oxidative Stress in Type 2 Diabetes Mellitus Patients with Chronic Periodontitis Under Non-Surgical Periodontal Therapy. A Double-Blind, Placebo-Controlled Trial // Diabetes Metab Syndr Obes. - 2020;6;13:19-29. https://doi.org/10.2147/DMSO.S230060

58. Tonetti M.S., Jepsen S., Jin L., Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action // J. of Clin. Periodontol. - 2017:7. https://doi.org/10.1111/jcpe.12732

59. Preshaw P.M., Taylor J., Jaedicke K.M. et al. Treatment of periodontitis reduces systemic inflammation in type 2 diabetes // J. Clin Periodontol. - 2020;47:737-746. https://doi.org/10.1111/jcpe.13274


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