employee
Nizhniy Novgorod, Nizhny Novgorod, Russian Federation
Nizhniy Novgorod, Nizhny Novgorod, Russian Federation
graduate student
Nizhniy Novgorod, Nizhny Novgorod, Russian Federation
student
Nihny Novgorod, Nizhny Novgorod, Russian Federation
GRNTI 76.29 Клиническая медицина
OKSO 31.05.03 Стоматология
BBK 566 Стоматология
Subject. A review of the literature devoted to one of the urgent problems of therapeutic dentistry — lip diseases. Objectives. Analysis of up-to-date information on lip diseases. Synthesis of the obtained data in a single concept. Methodology. The data of special literature were studied using scientific search library databases: PubMed, Elibrary, Cochrane, Google Scholar. Literature analysis was carried out on 45 sources. Results. In the modern world, diseases of the oral mucosa are widespread, among them lip diseases have a significant prevalence, many of which are insufficiently studied. Attempts have been repeatedly made to create a classification of heilites, however, as various authors note, there is no universally recognized classification today. The modern standard is the classification of ICD-10. Foreign researchers Kristina Pilipovich, Iva Crnarich, Mirna Shitum, Tomislav Duvanchich propose a new classification with the division of cheilitis into three groups (mainly reversible; mainly persistent; cheilitis associated with dermatoses or general somatic diseases). The special literature describes many aspects inherent in various types of cheilites. The modern direction of treatment of cheilitis is an integrated approach based on the joint implementation of general and local measures. Conclusions. To date, there is no universal treatment regimen for lip diseases, but many authors agree on the need to implement a combined treatment. This option with the use of different groups of drugs ensures the achievement of an effective result.
cheilitis, lip diseases, crack of a lip, treatment, classification
1. Anisimova I.V., Nedoseko V.B., Peremotin A.A. Kompleksnyy podhod k diagnostike i lecheniyu zabolevaniy gub. Institut stomatologii. 2006;30:84-87. [I.V. Anisimova, V.B. Nedoseko, A.A. Peremotin. An integrated approach to the diagnosis and treatment of lip diseases. Institute of Dentistry. 2006;30:84-87. (In Russ.)]. https://www.elibrary.ru/item.asp?id=15267515
2. Bakirtzi K., Papadimitriou I., Andreadis D., Sotiriou E., Ricci F. Treatment Options and Post-Treatment Malignant Transformation Rate of Actinic // Cheilitis: A Systematic Review. Academic Editor. Cancers (Basel). https://doi.org/10.3390/cancers13133354
3. Borovaya M.L., Gul'ko E.M. Analiz rasprostranennosti heylitov u detey. Stomatologiya XXI veka. Estafeta pokoleniy. Sb. trudov V nauchno - prakticheskoy konferencii molodyh uchenyh s mezhdunarodnym uchastiem. 2013;11:19. [M.L. Borovaya, E.M. Gulko. Analysis of the prevalence of cheilitis in children. Dentistry of the XXI century. Relay of generations. Collection of proceedings of the V scientific and Practical Conference of young scientists with international participation. 2013;11:19. (In Russ.)]. https://www.bsmu.by/files/5414/
4. Red. Borovskoy E.V., Mashkilleyson A.L. Zabolevaniya slizistoy obolochki polosti rta i gub. Uchebnoe posobie. Moskva : Izdatel'stvo MEDpress. 2001;320. [Eds. E.V. Borovskii, A.L. Mashkilleyson. Diseases of the mucous membrane of the oral cavity and lips. Textbook. Moscow : MEDpress Publishing House. 2001;320. (In Russ.)]. http://booksshare.net/index.php?id1=4&category=med&author=borovskiy-ev&book=zabolevaniye2001
5. Bhatia B.K., Bahr B.A., Murase J.E. Excimer laser therapy and narrowband ultraviolet B therapy for exfoliative cheilitis // International Journal of Women’s Dermatology. - 2015;1(2):95-98. DOI:https://doi.org/10.1016/j.ijwd.2015.01.006
6. Gazhva S.I., Dyatel A.V. Rasprostranennost' zabolevaniy slizistoy obolochki krasnoy kaymy gub u vzroslogo naseleniya Nizhegorodskoy oblasti. Fundamental'nye issledovaniya. 2014;10(6):1076-1080. [S.I. Gazhva, A.V. Dyatel. Prevalence of diseases of the mucous membrane of the red border of the lips in the adult population of the Nizhny Novgorod region. Fundamental research. 2014;10(6):1076-1080. (In Russ.)]. https://www.elibrary.ru/item.asp?id=22633950
7. Gawkrodger D.J. Investigation of reactions to dental materials // British Journal of Dermatology. - 2005;153(3):479-485. https://doi.org/10.1111/j.1365-2133.2005.06821.x
8. Georgakopoulou E., Loumou P., Grigoraki A., Panagiotopoulos A. Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03% // Medicina Oral Patologia Oral y Cirurgia Bucal. - 2021;26(3):357-360. https://doi.org/10.4317/medoral.24230
9. Gileva O.S., Smirnova E.N., Pozdnyakova A.A., Pozdeeva O.V., Libik T.V., Satyukova L.Ya., Halyavina I.N., Gorodilova E.A., Shilova T.Yu., Gibadullina N.V., Sadilova V.A., Nazukin E.D. Struktura, faktory riska i klinicheskie osobennosti zabolevaniy slizistoy obolochki polosti rta. Permskiy medicinskiy zhurnal. 2012;6:18-24. [O.S. Gileva, E.N. Smirnova, A.A. Pozdnyakova, O.V. Pozdeyeva, T.V. Libik, L.Ya. Satyukova, I.N. Khalyavina, E.A. Gorodilova, T.Y. Shilova, N.V. Gibadullina, V.A. Sadilova, E.D. Nazukin. Structure, risk factors and clinical features of diseases of the oral mucosa. Perm Medical Journal. 2012;6:18-24. (In Russ.)]. https://elibrary.ru/item.asp?id=18353380
10. Domic I., Budmir J., Novak I., Mravak-Stipetic M., Lugovic-Mihic L. Assessment of allergies to food and additives in patients with angioedema, burning mouth syndrome, cheilitis, gingivostomatitis, oral lichenoid reactions, and perioral dermatitis // Acta Clin Croat. - 2021;60(2):276-281. https://doi.org/10.20471/acc.2021.60.02.14
11. Kirzhinova E.M. Gemodinamicheskie i mikrobiologicheskie aspekty mestnoy terapii samostoyatel'nyh zabolevaniy krasnoy kaymy gub ; avtoref. diss. … kand. med. Nauk. 14.01.14. [Mesto zaschity GBOU VPO «Volgogradskiy gosudarstvennyy medicinskiy universitet»]. Volgograd, 2015. [E.M. Kirzhinova. Hemodynamic and microbiological aspects of local therapy of independent diseases of the red border of the lips : abstract. diss. ... candidate of medical Sciences. 14.01.14. [Place of defense of the Volgograd State Medical University]. Volgograd, 2015. (In Russ.)]. https://www.dissercat.com/content/gemodinamicheskie-i-mikrobiologicheskie-aspekty-mestnoi-terapii-samostoyatelnykh-zabolevanii
12. Kriheli N.I., Brusenina N.D., Rybalkina E.A., Pustovoyt E.V. Zabolevaniya gub. Uchebnoe posobie. Moskva : Izdatel'stvo Prakticheskaya medicina. 2016:112. [N.I. Krikheli, N.D. Brusenina, E.A. Rybalkina, E.V. Pustovoit. Diseases of the lips. Textbook. Moscow : Practical Medicine Publishing House. 2016:112. (In Russ.)]. https://www.labirint.ru/books/508223/
13. Kudashkina N.V., Aver'yanov S.V., Zubareva A.V., Ishakov I.R. Razrabotka mazi dlya lecheniya heylitov u studentov s zubochelyustnymi anomaliyami. Sovremennye problemy nauki i obrazovaniya. 2016;2. [N.V. Kudashkina, S.V. Averyanov, A.V. Zubareva, I.R. Iskhakov. Development of ointment for the treatment of cheilitis in students with dental anomalies. Modern problems of science and education. 2016;2. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25869856
14. Lugovic-Mihic L., Ilic I., Budimir J., Pondeljak N., Mravak Stipetic M. Common allergies and allergens in oral and perioral diseases // Acta Clin Croat. - 2020;59(2):318-328. https://doi.org/10.20471/acc.2020.59.02.16
15. Lugovic-Mihic L., Pilipovic K., Crnaric I., Situm M., Duvancic T. Differential Diagnosis of Cheilitis - How to Classify Cheilitis? // Acta Clin Croat. - 2018;57(2):342-351. https://doi.org/10.20471/acc.2018.57.02.16
16. Luckaya I.K. Allergicheskaya i atopicheskaya reakcii kozhi i slizistoy obolochki polosti rta. Sovremennaya stomatologiya. 2013;2:14-17. [I.K. Lutskaya. Allergic and atopic reactions of the skin and oral mucosa. Modern dentistry. 2013;2:14-17. (In Russ.)]. https://www.elibrary.ru/item.asp?id=21623677
17. Luckaya I.K. Klinicheskie proyavleniya samostoyatel'nyh zabolevaniy gub. Medicinskie novosti. 2011;11:4-8. [I.K. Lutskaya. Clinical manifestations of independent lip diseases. Medical news. 2011;11:4-8. (In Russ.)]. https://www.elibrary.ru/item.asp?id=17070494
18. Maksimenko P.T., Skripnikova T.P., Hmil' T.A. Nomenklatura, klinicheskaya klassifikaciya bolezney, izmeneniy slizistoy obolochki polosti rta, gub i yazyka. Ukrains'kiy stomatologichniy al'manah. 2008;4:28-35. [P.T. Maksimenko, T.P. Skripnikova, T.A. Khmel Nomenclature, clinical classification of diseases, changes in the mucous membrane of the oral cavity, lips and tongue. Ukrainian dental Almanac. 2008;4:28-35. (In Russ.)]. https://www.elibrary.ru/item.asp?id=23221886
19. Mezhdunarodnaya klassifikaciya bolezney (10-y peresmotr). Klassifikaciya psihicheskih i povedencheskih rasstroystv: MKB-10 Klinich. opisaniya i ukazaniya po diagnostike. VOZ. Spb. : Izdatel'stvo Overlayd. 1994:303. [International Classification of Diseases (10th revision). Classification of mental and behavioral disorders: ICD-10 Clinic. descriptions and diagnostic instructions. WHO. St. Petersburg : Overlaid Publishing House. 1994:303. (In Russ.)]. https://webmed.irkutsk.ru/doc/pdf/icd10ps.pdf
20. Mihal'chenko A.V., Medvedeva E.A., Mihal'chenko D.V. Osobennosti struktury zabolevaniy slizistoy obolochki polosti rta u zhiteley Volgograda i Volgogradskoy oblasti. Volgogradskiy nauchno-medicinskiy zhurnal. 2016;1:3-7. [A.V. Mikhalchenko, E.A. Medvedeva, D.V. Mikhalchenko. Features of the structure of diseases of the oral mucosa in residents of Volgograd and the Volgograd region. Volgograd Scientific and Medical Journal. 2016;1:3-7. (In Russ.)]. https://www.elibrary.ru/item.asp?id=27249155
21. Mishutina O.L., Shashmurina V.R. Atopicheskiy heylit v praktike vracha-stomatologa. Smolenskiy medicinskiy al'manah. 2021;2:105-108. [O.L. Mishutina, V.R. Shashmurina. Atopic cheilitis in the practice of a dentist. Smolensk Medical Almanac. 2021;2:105-108. (In Russ.)]. https://www.elibrary.ru/item.asp?id=46233619
22. Mishutina O.L., Shashmurina V.R. Atopicheskiy heylit u detey (obzor literatury). Smolenskiy medicinskiy al'manah. 2020;4:146-149. [O.L. Mishutina, V.R. Shashmurina. Atopic cheilitis in children (literature review). Smolensk Medical Almanac. 2020;4:146-149. (In Russ.)]. https://www.elibrary.ru/item.asp?id=44643221
23. Mocanu M., Vata D., Alexa A.-I., Trandafir L., Patrascu A.-I., Hancu M. F., Gheuca-Solovastru L. Atopic Dermatitis-Beyond the Skin // Diagnostics (Basel). - 2021;11(9). https://doi.org/10.3390/diagnostics11091553
24. Muhamedzhanova L.R. Konstitucional'nye osobennosti gub kak prognosticheski znachimyy faktor pri zabolevaniyah krasnoy kaymy. Prakticheskaya medicina. 2012;8(64):55-57. [L.R. Mukhamedzhanova. Constitutional features of the lips as a prognostically significant factor in diseases of the red border. Practical medicine. 2012;8(64):55-57. (In Russ.)]. https://www.elibrary.ru/item.asp?id=18376803
25. de Oliveira Silva L.V., de Arruda J.A.A., Abreu L.G. et al. Demographic and Clinicopathologic Features of Actinic Cheilitis and Lip Squamous Cell Carcinoma: a Brazilian Multicentre Study // Head and Neck Pathology. - 2020;14(4):899-908. https://doi.org/10.1007/s12105-020-01142-2
26. Parlagashvili M.M. Ocenka sostoyaniya krasnoy kaymy i slizistoy obolochki gub u molodezhi 20-27 let. Stomatologiya. 2015;94(6):58. [M.M. Parlagashvili. Assessment of the condition of the red border and the mucous membrane of the lips in young people aged 20-27 years. Dentistry. 2015;94(6):58. (In Russ.)]. https://elibrary.ru/item.asp?id=25458563
27. Rabinovich I.M., Rabinovich O.F., Abramova E.S., Denisova M.A. Kliniko-patogeneticheskie aspekty razlichnyh form heylita. Stomatologiya. 2016;1:67-72. [I.M. Rabinovich, O.F. Rabinovich, E.S. Abramova, M.A. Denisova. Clinical and pathogenetic aspects of various forms of cheilitis. Dentistry. 2016;1:67-72. (In Russ.)]. https://www.elibrary.ru/item.asp?id=25675500
28. Rodriguez-Archilla A., Irfan-Bhatti A. Risk factors for actinic cheilitis: A meta-analysis // Journal Dental Research Dental Clinics Dental Prospects. - 2021;15(4):285-289. https://doi.org/10.34172/joddd.2021.047
29. Samimi M. Cheilites : orientation diagnostique et traitement // La Presse Medicale. - 2016;45(2):240-250. https://doi.org/10.1016/j.lpm.2015.09.024
30. Skripkin Yu.K., Kubanova A.A., Akimov V.G. Kozhnye i venericheskie bolezni. Uchebnoe posobie. Moskva : Izdatel'stvo GEOTAR-Media. 2012:544. [Yu.K. Skripkin, A.A. Kubanova, V.G. Akimov. Skin and venereal diseases. Study guide. Moscow : GEOTAR-Media Publishing House. 2012:544. (In Russ.)]. https://www.labirint.ru/books/285511/
31. de Sousa Lopes M.L.D., da Silva Junior F.L., Costa Lima K., de Oliveira P.T., da Silveira E.J.D. Clinicopathological profile and management of 161 cases of actinic cheilitis // Anais Brasileiros Dermatologia. - 2015;90(4):505-512. https://doi.org/10.1590/abd1806-4841.20153848
32. Tkach S.S., Yanovskiy L.M. Patologiya krasnoy kaymy, slizistoy i kozhi gub: sovremennoe sostoyanie voprosa. Sibirskiy medicinskiy zhurnal. 2006;2:10-13. [S.S. Tkach, L.M. Yanovsky. Pathology of the red border, mucous membrane and skin of the lips: the current state of the issue. Siberian Medical Journal. 2006;2:10-13. (In Russ.)]. https://www.elibrary.ru/item.asp?id=11529878
33. Tortorici S., Corrao S., Natoli G., Difalco P. Prevalence and distribution of oral mucosal non-malignant lesions in the western Sicilian population // Minerva Stomatologica. - 2016;65(4):191-206. PMID: 27374359
34. Tuncer Budanur D., Cengizhan Yas M., Sepet E. Potential hazards due to food additives in oral hygiene products // Journal of Istanbul University Faculty of Dentistry. - 2016;50(2):60-69. https://doi.org/10.17096/jiufd.72103
35. Uspenskaya O.A. Primenenie ataraksa i eplana v kompleksnom lechenii hronicheskogo recidiviruyuschego aftoznogo stomatita. Universum: medicina i farmakologiya. 2015;2(15):4. [O.A. Uspenskaya. The use of atarax and eplan in the complex treatment of chronic recurrent aphthous stomatitis. Universum: Medicine and Pharmacology. 2015;2(15):4. (in Russ.)]. https://www.elibrary.ru/item.asp?id=22912877
36. Pod red. Uspenskoy O.A., Zhuleva E.N. Zabolevaniya slizistoy obolochki polosti rta. Uchebnoe posobie. N. Novgorod : Izdatel'stvo Nizhegorodskoy gosudarstvennoy medicinskoy akademii. 2017:504. [Eds. O.A. Uspenskaya, E.N. Zhuleva. Diseases of the oral mucosa. Study guide. N. Novgorod: Publishing House of the Nizhny Novgorod State Medical Academy. 2017:504. (In Russ.)]. https://search.rsl.ru/ru/record/01008840741
37. Uspenskaya O.A., Zhdanova M.L., Nazarova E.S. Kollagensoderzhaschiy gidrogel' dlya lecheniya hronicheskoy recidiviruyuschey treschiny guby. Dental forum. 2019;3(74):35-38. [O.A. Uspenskaya, M.L. Zhdanova, E.S. Nazarova. Collagen-containing hydrogel for the treatment of chronic recurrent lip crack. Dental forum. 2019;3(74):35-38. (In Russ.)]. https://www.elibrary.ru/item.asp?id=39144612
38. Uspenskaya O.A., Tiunova N.V., Zhdanova M.L., Zardiashvili I.Z., Timina E.Yu. Klinicheskiy sluchay mestnogo lecheniya hronicheskoy treschiny nizhney guby. Zdorov'e i obrazovanie v XXI veke. 2019;21(4):82-86. [O.A. Uspenskaya, N.V. Tiunova, M.L. Zhdanova, I.Z. Zardiashvili, E.Yu. Timina. A clinical case of local treatment of chronic lower lip fracture. Health and education in the XXI century. 2019;21(4):82-86. (In Russ.)]. https://www.elibrary.ru/item.asp?id=38478218
39. Uspenskaya O.A., Kruglova N.V. Obosnovanie primeneniya vitamina U pri kompleksnom lechenii zabolevaniy gub. Dental forum. 2019;2(73):35-37. [O.A. Uspenskaya, N.V. Kruglova. Justification of the use of vitamin U in the complex treatment of lip diseases. Dental forum. 2019;2(73):35-37. (In Russ.)]. https://www.elibrary.ru/item.asp?id=37307598
40. Uspenskaya O.A., Kruglova N.V. Primer kompleksnogo lecheniya sochetannoy patologii gub (klinicheskiy sluchay). Cathedra-kafedra. Stomatologicheskoe obrazovanie. 2019;68:42-44. [O.A. Uspenskaya, N.V. Kruglova. Example of complex treatment of combined pathology of the lips (clinical case). Cathedra-department. Dental education. 2019;68:42-44. (In Russ.)]. https://www.elibrary.ru/item.asp?id=42467050
41. Uspenskaya O.A., Spiridonova S.A. Ocenka kachestva kompozitnoy restavracii v zavisimosti ot abrazivnosti polirovochnyh past. Problemy stomatologii 2021;2(17):57-61. [O.A. Uspenskaya, S.A. Spiridonova. Estimation of the quality of composite restoration depending on the abrasivity of polishing pasts. Actual problems in dentistry. 2021;2(17):57-61. (In Russ.)]. https://www.elibrary.ru/item.asp?id=46411882
42. Fedotov V.P. Fotodermatozy (klinicheskaya lekciya). Dermatovenerologiya. Kosmetologiya. Seksopatologiya. 2015;3-4:143-157. [V.P. Fedotov. Photodermatoses (clinical lecture). Dermatovenerology. Cosmetology. Sexopathology. 2015;3-4:143-157. (In Russ.)]. https://www.elibrary.ru/item.asp?id=26697237
43. Shulman J.D. Prevalence of oral mucosal lesions in children and youths in the USA // International Journal of Paediatric Dentistry. - 2005;15(2):89-97. https://doi.org/10.1111/j.1365-263X.2005.00632.x
44. El Toum S., Cassia A., Bouchi N., Kassab I. Prevalence and Distribution of Oral Mucosal Lesions by Sex and Age Categories: A Retrospective Study of Patients Attending Lebanese School of Dentistry // International Journal of Dentistry. - 2018,5:1-7. https://doi.org/10.1155/2018/4030134
