Abstract and keywords
Abstract (English):
To date, there is a limited amount of literature that describes the use of oral therapeutic and prophylactic drugs in patients with a confirmed diagnosis of SARS-CoV-2. Therefore, this topic is relevant. Thus, the purpose of this study was to study the effectiveness of the use of therapeutic and prophylactic agents in patients with a laboratory-confirmed diagnosis of mild to moderate SARS-CoV-2, with or without concomitant oral co-infection. The data of the conducted study will constitute an important stage in the algorithm of specialized therapy. Materials and methods. A comparative analysis of the use of therapeutic and prophylactic agents for the oral cavity in patients with a confirmed diagnosis of SARS-CoV-2 was carried out. The conclusions are based on the results of a clinical study that compared the effectiveness of the use of therapeutic and prophylactic agents in 90 patients aged 20 to 87 years with mild to moderate Sars-CoV-2 with oral co-infection and 15 patients aged from 20 to 87 years of age with mild to moderate Sars-CoV-2 without coinfection. Results. During the study, the following results were obtained. The most effective drug was a solution of aqueous chlorhexidine 0.5%, but there was a side effect in the form of xerostomia. The Miramistin solution also had high efficiency, and the lowest efficiency was observed when using the Rotokan solution. Conclusions. The data of the conducted study will constitute an important stage in the algorithm of specialized therapy.

SARS-CoV-2, coronavirus, oral cavity, coinfection, plaque, aqueous chlorhexidine, miramistin, rotocan

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