Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
Vital pulp therapy is a biologic and conservative treatment to preserve the vitality and function of the pulp tissue. Indirect pulp capping is one of the techniques which can be done with Ca(OH)2. The success rate of using Ca(OH)2 during treatment of reversible pulpitis isn’t so high. And the reactivity of the vital pulp is reduced when exposed to an aggressive calcium hydroxide-based material. According to the international classification of diseases, reversible pulpitis is considered as K04.00 – initial pulpitis. The purpose of this review article is to assess systematically the available scientific evidence about the clinical response of pulp-dentin complex after using Ca(OH)2 for indirect pulp capping. Materials and methods: The study of publications was produced in the electronic databases such as Google Scholar, PubMed during a systematic review of the literature. Included articles contain information about using Ca(OH)2 during treatment of initial pulpitis and its side effects. The publication date criterion was selected from January 2011 to July 2021. Results: 55 articles were viewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 10. Conclusions: According to literature data, the using calcium hydroxide for indirect pulp capping during treatment of the reversible (initial) pulpitis is decreasing due to the side effects and clinical response from dentin pulp complex.
Ca(OH)2, indirect pulp capping, reversible (initial) pulpitis, vital pulp therapy, dentinal bridge formation
1. Takashi K., Qiang Z., Robert E., Yohji I. Current status of direct pulp-capping materials for permanent teeth // Dental Materials Journal. - 2016;35(1):1-12. https://doi.org/10.4012/dmj.2015-013
2. Najmeh A., Abbasali K. Outcomes of vital pulp therapy in permanent teeth with different medicaments based on review of the literature // Dent Res J. - 2015;12(5):406-417. doi:https://doi.org/10.4103/1735-3327.166187
3. Jamileh G., Maryam F., Iman P. New Approaches in Vital Pulp Therapy in Permanent Teeth // Iran Endod J. - 2014;9(1):15-22. PMID: 24396371
4. Marina A.P., Fadi A.A., Alexander W., Mohammed B.A., Mohammed A., Christian H.S. A randomized clinical trial on the use of medical Portland cement, MTA and calcium hydroxide in indirect pulp treatment // Clin Oral Investig. - 2014;18(5):1383-1389. DOI:https://doi.org/10.1007/s00784-013-1107-z
5. Fatou L.B., Fatou G.N., Abdoul W.K., Henri M.B., Pierre F. Evaluation of mineral trioxide aggregate (MTA) versus calcium hydroxide cement (Dycal(®) ) in the formation of a dentine bridge: a randomised controlled trial // Int Dent J. - 2012;62(1):33-39. doi:https://doi.org/10.1111/j.1875-595X.2011.00084.x
6. Nestor C., Avina P., Joel B. Vital pulp therapy // Dent Clin North Am. - 2013;57(1):59-73. doi:https://doi.org/10.1016/j.cden.2012.09.004
7. Cenkhan B., Nurhan O., Mehmet C., Emre B. Immunolocalization of fibronectin during reparative dentinogenesis in rat molor teeth after pulp capping with mineral trioxide aggregate or calcium hydroxide // N Y State Dent J. - 2011;77(6):36-42. PMID: 22338817
8. Chawan M., Chavin J., Sujin C., Noppadol S.-A.-I., Rangsini M., Prasit P., Thantrira P., Thanaphum O. Human dental pulp stem cell responses to different dental pulp capping materials // BMC Oral Health. - 2021;21(1):209. doi:https://doi.org/10.1186/s12903-021-01544-w
9. Elzbieta L.-C., Grazyna M.-K., Malgorzata P., Marta O., Adam H. Evaluation of cytotoxicity and pH changes generated by various dental pulp capping materials - an in vitro study // Folia Histochem Cytobiol. - 2017;55(2):86-93. doi:https://doi.org/10.5603/FHC.a2017.0008
10. Călin D.L., Dragomir R., Giuroiu C.L. Clinical and radiographic evaluation of indirect pulp capping with MTA and calcium hydroxide for permanent teeth // Romanian Journal of Medical and Dental Education. - 2019;8;3. https://d1wqtxts1xzle7.cloudfront.net/59485719/CLINICAL-AND-RADIOGRAPHIC-EVALUATION-OF-INDIRECT-PULP-CAPPING-WITH-MTA-AND-CALCIUM-HYDROXIDE-FOR-PERMANENT-TEETH20190602-33988-u4cth0-with-cover-page-v2.pdf?Expires=1642546481&Signature=CP6oJWV3jecBby8fk2ABe~EQYdQ9H8En7l6tuWIHxjxPfSruIP6bWlOaBT4bObjLxMQZfVzZx--Z0~ti6jLVvGTpJq8x0ImdTFQdnP7jqz7VhIzhbtZ5pujuh8r6YZ6RiqimliQFgkZ-AhJ8RZLvsMXi93ZbeJVEtAI9AZbecOmy7gukQN4mbeRtG4JaLHfA8kbWGX87Nd0UV74T5m7xJjjjKr0n5YeIHgpVOJDYXRY4gFENS3t8ZjEUECzA0o-dArRjz9fyjOaYsb5bHL6F91ROGKnNcb7u1zZXlUhvxxixaeTXbXDPmI09b3wPEmohxyg7h2hfDwqDzQ8YUJhIBQ__&Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA
11. Rafeza S., Mozammal H., Shamsul A. Evaluation of clinical and radiological outcomes of mineral trioxide aggregate and calcium hydroxide as indirect pulp capping agents in the treatment of deep carious lesion of permanent teeth // Bangabandhu Sheikh Mujib Medical University Journal. - 2016;9(3):140-145. https://doi.org/10.3329/bsmmuj.v9i3.29462
