CLINICAL AND LABORATORIAL RESEARCH IN PHYSICAL-CHEMICAL CHARACTERISTICS OF NEW TOOTHPASTE WITH HYALURON-TI FORTE COMPLEX
Abstract and keywords
Abstract (English):
Subject. Physical-chemical characteristics of the toothpaste Dentaswiss Extra Whitening and structural and optical parameters of mixed saliva before and after volunteer brushing. Objectives. To evaluate physical-chemical characteristics of the new therapeutic and prophylactic toothpaste Dentaswiss Extra Whitening together with changes in structural and optical parameters of the effected mixed saliva. Methodology. The composition and properties of the new therapeutic and prophylactic toothpaste Dentaswiss Extra Whitening are studied based on the results of physical and chemical analysis of three aqueous solutions (prepared with different concentrations) by measuring pH value, calcium ion concentration, electrical conductivity and surface tension. The study involved 32 student volunteers of both sexes (men — 11, women — 21) from the Ural State Medical University Faculty of Dentistry between the ages of 21 to 23 who were comprehensively examined including structural and optical parameters of mixed saliva before and after brushing. Results. The average pH value is 7.91±0.01, the increased calcium ion (Са2+) level is found up to 2.25 mmol/l in all three aqueous suspensions (р≤0.05). Electrical conductivity of suspensions is found to be increased and surface tension is found to be reduced uniformly with the increase in mass fraction (р≤0.05). Conclusion. The study of physical-chemical characteristics of the toothpaste Dentaswiss Extra showed positive changes in pH values, electrical conductivity and surface tension promoting the increased remineralizing properties of mixed saliva (р≤0.05).

Keywords:
the toothpaste Dentaswiss Extra Whitening, mixed saliva, physical-chemical characteristics of the toothpaste, crystal prismatic structures, microcrystallization of saliva
References

1. Vagner V.D., Avraamova O.G., Shevchenko O.V. Profilakticheskaya deyatel'nost' i ee zakonodatel'noe i normativnoe pravovoe obespechenie. Sovremennaya stomatologiya: ot tradiciy k innovaciyam. Materialy Mezhdunarodnoy nauchno-prakticheskoy konferencii. 2018:85-89. [V.D. Vagner, O.G. Avraamova, O.V. Shevchenko. Preventive care and its legislative and statutory support. Collection: Modern Dentistry: from traditions to innovations. Materials of International Applied Science Conference. 2018:85-89. (In Russ.)].

2. Guseva M.S. Ocenka organolepticheskih svoystv zubnoy pasty dlya chuvstvitel'nyh zubov s ftoridom olova. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy IV Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, IV Foruma medicinskih i farmacevticheskih vuzov Rossii «Za kachestvennoe obrazovanie», posvyaschennye 100-letiyu so dnya rozhdeniya rektora Sverdlovskogo gosudarstvennogo medicinskogo instituta, professora Vasiliya Nikolaevicha Klimova. 2019:1051-1054. [M.S. Guseva. Analysis of organoleptic properties of the toothpaste for sensitive teeth with tin fluorides. Collection: Actual issues of modern medical science and healthcare. Materials of IV International Applied Science Conference of young scientists and students, IV Forum of Russian medical and pharmaceutical higher educational institutions “Quality Education” devoted to the 100th anniversary of Professor Vasily N. Klimov, the head of Sverdlovsk State Medical Institute. 2019:1051-1054. (In Russ.)].

3. Elovikova T.M., Ermishina E.Yu., Koscheev A.S. Analiz vozdeystviya lechebno-profilakticheskoy zubnoy pasty, soderzhaschey bikarbonat i ftorid natriya, na sostoyanie organov polosti rta pri vospalitel'nyh zabolevaniyah parodonta u molodyh pacientov (Kliniko-laboratornoe issledovanie). Parodontologiya. 2019;24;1-24(90):45-51. [T.M. Elovikova, E.Y. Ermishina, A.S. Koscheev. Impact analysis of the therapeutic and prophylactic toothpaste with sodium bicarbonate and sodium fluoride on the oral conditions of young patients with periodontium inflammations (Clinical laboratory testing). Periodontology. 2019;24;1-24(90):45-51. (In Russ.)]. https://elibrary.ru/item.asp?id=37096138

4. Elovikova T.M., Ermishina E.Yu., Uvarova L.V., Koscheev A.S. Obosnovanie primeneniya lechebno-profilakticheskoy zubnoy pasty s ftoridom natriya dlya chuvstvitel'nyh zubov u pacientov s giperesteziey i vospalitel'nymi zabolevaniyami parodonta. Aktual'nye voprosy stomatologii. Sbornik nauchnyh trudov, posvyaschennyy osnovatelyu kafedry ortopedicheskoy stomatologii KGMU professoru Isaaku Mihaylovichu Oksmanu. 2019:129-133. [T.M. Elovikova, E.Y. Ermishina, L.V. Uvarova, A.S. Koscheev. Rational for use of the therapeutic and prophylactic toothpaste sodium fluoride for sensitive teeth for patients with hypertension and periodontium inflammations. Dentistry Issues. Collection of academic paper devoted to Isaak Mikhailovich Oksman, the founder of Orthopedic Dentistry Department of Kazan State Medical University. 2019:129-133. (In Russ.)].

5. Elovikova T.M., Ermishina E.Yu., Uvarova L.V., Koscheev A.S. Reshenie problemy povyshennoy chuvstvitel'nosti dentina: mehanizmy remineralizacii pri kursovom ispol'zovanii zubnoy pasty s ftoridom olova. Stomatologiya. 2019;98;5:66-71. [T.M. Elovikova, E.Y. Ermishina, L.V. Uvarova, A.S. Koscheev. Solutions to dentin hypersensitivity: remineralization mechanisms for medication course of the toothpaste with tin fluorides. Dentistry. 2019;98;5:66-71. (In Russ.)]. https://elibrary.ru/item.asp?id=41314058

6. Elovikova T.M., Sablina S.N., Grigor'ev S.S., Koscheev A.S., Gosteeva A.V., Denisenko R.V. Kachestvennye i kolichestvennye harakteristiki ftoridsoderzhaschey zubnoy pasty s antisepticheskim effektom. Materialy Mezhdunarodnogo kongressa «Stomatologiya Bol'shogo Urala». 2020:46-48. [T.M. Elovikova, S.N. Sablina, S.S. Grigorjev, A.S. Koscheev, A.V. Gosteeva, R.V. Denisenko. Qualitative and quantitative characteristics of fluoride-based antiseptic toothpaste. Collection: Materials of International Congress Dentistry of the Great Ural. 2020:46-48. (In Russ.)].

7. Karaseva V.V., Elovikova T.M., Koscheev A.S. Ocenka stomatologicheskogo statusa, kontrolya individual'noy gigieny i kachestva zhizni pacientov s defektami chelyustey v sochetanii s medikamentozno associirovannym osteonekrozom. Stomatologiya. 2020;99;5:80-86. [B.B. Karaseva, T.M. Elovikova, A.S. Koscheev. Analysis of dental status, personal hygiene control and life quality of patients with jaw deformities in combination with drug-induced osteonecrosis. Dentistry. 2020;99;5:80-86. (In Russ.)].

8. Kuz'mina E.M., Yanushevich O.O. Tendencii rasprostranennosti i intensivnosti kariesa zubov sredi naseleniya Rossii za 20-letniy period. Dental Forum. 2020;3(78):2-8. [E.M. Kuzmina, O.O. Yanushevich. Caries prevalence and intensity in population of Russia for the last two decades. Dental Forum. 2020;3(78):2-8. (In Russ.)]. https://elibrary.ru/item.asp?id=43825063

9. Medvedeva Yu.V., Ponomareva A.A. Ocenka effektivnosti primeneniya otechestvennoy zubnoy pasty na osnove trav u pacientov s saharnym diabetom 2 tipa. IV Vserossiyskoe rabochee soveschanie po problemam fundamental'noy stomatologii. 2016:98-100. [Y.V. Medvedeva, A.A. Ponomareva. Efficacy evaluation of use of the local herbal toothpaste for patients with Type 2 diabetes. IV All-Russian working session for fundamental dentistry issues. 2016:98-100. (In Russ.)].

10. Ozerov D.D. Osobennosti obturacii dentinnyh kanal'cev pri ispol'zovanii zubnoy pasty s ftoridom olova. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy III Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, III Foruma medicinskih i farmacevticheskih vuzov Rossii «Za kachestvennoe obrazovanie». 2018:228-231. [D.D. Ozerov. Specifics of obturation of dentinal canals using the toothpaste with tin fluorides. Actual issues of modern medical science and healthcare. Materials of III International Applied Science Conference of young scientists and students, III Forum of Russian medical and pharmaceutical higher educational institutions “Quality Education”. 2018:228-231. (In Russ.)].

11. Prihodkin A.S. Ocenka processa remineralizacii zubnoy emali pri kursovom ispol'zovanii zubnoy pasty dlya chuvstvitel'nyh zubov s ftoridom natriya. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy III Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, III Foruma medicinskih i farmacevticheskih VUZov Rossii «Za kachestvennoe obrazovanie». 2018:250-255. [A.S. Prikhodkin. Analysis of teeth enamel remineralization with medication course of the toothpaste with sodium fluoride for sensitive teeth. Actual issues of modern medical science and healthcare. Materials of III International Applied Science Conference of young scientists and students, III Forum of Russian medical and pharmaceutical higher educational institutions “Quality Education”. 2018:250-255. (In Russ.)].

12. Potockaya A.D. Osobennosti processa remineralizacii emali zuba pri ispol'zovanii zubnoy pasty, soderzhaschey akvakompleks glicerosol'vata titana. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy IV Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, IV Foruma medicinskih i farmacevticheskih vuzov Rossii «Za kachestvennoe obrazovanie», posvyaschennye 100-letiyu so dnya rozhdeniya rektora Sverdlovskogo gosudarstvennogo medicinskogo instituta, professora Vasiliya Nikolaevicha Klimova. 2019:1193-1197. [A.D. Pototskaya. Specifics of teeth enamel remineralization using the toothpaste with titanium glycerosolvate aquacomplex. Actual issues of modern medical science and healthcare. Materials of IV International Applied Science Conference of young scientists and students, IV Forum of Russian medical and pharmaceutical higher educational institutions “Quality Education” devoted to the 100th anniversary of Professor Vasily N. Klimov, the head of Sverdlovsk State Medical Institute. 2019:1193-1197. (In Russ.)].

13. Reyn P.A. Laboratornoe issledovanie fiziko-himicheskih svoystv novoy otechestvennoy zubnoy pasty s gidroksiapatitom kal'ciya. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy V Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, posvyaschennoy 75-letiyu Pobedy v Velikoy Otechestvennoy voyne, 90-letiyu UGMU i 100-letiyu medicinskogo obrazovaniya na Urale. 2020:295-299. [P.A. Rein. Laboratory assessment of physical-chemicals properties of the new local toothpaste with calcium hydroxylapatite. Actual issues of modern medical science and healthcare. Materials of V International Applied Science Conference of young scientists and students devoted to the 75th anniversary of Victory in the Great Patriotic War, 90th anniversary of Ural State Medical Uneversity and 100th anniversary of medical education in the Urals. 2020:295-299. (In Russ.)].

14. Smirnova T.S. Ocenka membrannoy provodimosti kal'ciysoderzhaschih komponentov novyh lechebno-profilakticheskih zubnyh past, soderzhaschih akvakompleks glicerosol'vata titana. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy V Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, posvyaschennoy 75-letiyu Pobedy v Velikoy Otechestvennoy voyne, 90-letiyu UGMU i 100-letiyu medicinskogo obrazovaniya na Urale. 2020:310-315. [T.S. Smirnova. Analysis of membrane conductance of calcium-based components of new therapeutic and prophylactic toothpastes with titanium glycerosolvate aquacomplex. Actual issues of modern medical science and healthcare. Materials of V International Applied Science Conference of young scientists and students devoted to the 75th anniversary of Victory in the Great Patriotic War, 90th anniversary of Ural State Medical Uneversity and 100th anniversary of medical education in the Urals. 2020:310-315. (In Russ.)].

15. Strokina E.S. Izmeneniya parametrov smeshannoy slyuny u kuril'schikov posle primeneniya novoy vosstanavlivayuschey emal' gelevoy zubnoy pasty. Materialy Mezhdunarodnogo kongressa «Stomatologiya Bol'shogo Urala». 2020:125-127. [E.S. Strokina. Changes in smoker’s mixed saliva after using new enamel repair gel toothpaste. Materials of International Congress Dentistry of the Great Ural. 2020:125-127. (In Russ.)].

16. Strokina E.S., Kostina E.Yu., Tancyreva S.N. Izmeneniya mikrokristallizacii smeshannoy slyuny posle odnokratnogo vozdeystviya novoy protivovospalitel'noy zubnoy pasty s bikarbonatom natriya i dioksidom kremniya. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy III Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, III Foruma medicinskih i farmacevticheskih vuzov Rossii «Za kachestvennoe obrazovanie». 2018:314-317. [E.S. Strokina, E.Y. Kostina, S.N. Tantsyreva. Changes in mixed saliva microcrystallization after a single use of the new anti-inflammatory toothpaste with sodium bicarbonate and silica dioxide. Actual issues of modern medical science and healthcare. Materials of III International Applied Science Conference of young scientists and students, III Forum of Russian medical and pharmaceutical higher educational institutions “Quality Education”. 2018:314-317. (In Russ.)].

17. Frolova D.V. Issledovanie fiziko-himicheskih svoystv dispersnyh vodnyh sistem zubnoy pasty s hloridom natriya i glicerofosfatom kal'ciya. Aktual'nye voprosy sovremennoy medicinskoy nauki i zdravoohraneniya. Materialy V Mezhdunarodnoy nauchno-prakticheskoy konferencii molodyh uchenyh i studentov, posvyaschennoy 75-letiyu Pobedy v Velikoy Otechestvennoy voyne, 90-letiyu UGMU i 100-letiyu medicinskogo obrazovaniya na Urale. 2020:343-347. [D.V. Frolova. Studying physical and chemical properties of aqueous dispersions of the toothpaste with sodium chlorides and calcium glycerophosphate. Actual issues of modern medical science and healthcare. Materials of V International Applied Science Conference of young scientists and students devoted to the 75th anniversary of Victory in the Great Patriotic War, 90th anniversary of Ural State Medical University and 100th anniversary of medical education in the Urals. 2020:343-347. (In Russ.)].

18. Akwagyiram I., Amini P., Bosma M., Wang N., Gallob J. Efficacy and tolerability of sodium bicarbonate toothpaste in subjects with gingivitis: a 6 month randomized controlled study // Oral Health Prev Dent. - 2018;16:401-409.

19. Bosma M., Milleman K., Akwagyiram I., Targett D., Milleman J. A randomised controlled trial to evaluate the plaque removal efficacy of sodium bicarbonate dentifrices in a single brushing clinical model // BDJ Open. - 2018;4(1):17-23.

20. Chapple I., Mealey B., Van Dyke T., Bartold P. et al. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions // J Clin Periodontol. - 2018;6(2):68-77.

21. Lomax A., Patel S., Wang N., Kakar K., Kakar A., Bosma M. A randomized controlled trial evaluating the efficacy of a 67% sodium bicarbonate toothpaste on gingivitis // Int J Dent Hyg. - 2016;3(1):290-296.

22. Mason S., Karwal R., Bosma M. Two randomized clinical studies to confirm differential plaque removal by sodium bicarbonate dentifrices in a single timed brushing model // J Clin Dent. - 2017;28:44-48.

23. Shivasakthy M., Sethuraman K., Usha C. et al. Improving the quality and future directions of dental education // J Sci Dent. - 2016;6(1):1-5.

24. Smiley C., Tracy S., Abt E., et al. Evidence based clinical practice guideline on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts // J Am Dent Assoc. - 2015;146:525-539.

25. Valkenburg C., Kashmour Y., Dao A., Fridus Van der Weijden G. et al. The efficacy of baking soda dentifrice in controlling plaque and gingivitis a systematic review // Int J Dent Hyg. - 2019;17(2):99-116.


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