THE FREQUENCY OF COMBINATION OF ORAL LICHEN PLANUS WITH SOMATIC PATHOLOGY AND LOCAL UNFAVORABLE FACTORS OF THE ORAL CAVITY
Abstract and keywords
Abstract (English):
Background. In this article, we studied the frequency of combination of oral lichen planus with somatic pathology. The analysis of the survey, testing of individuals with oral lichen planus, laboratory blood counts; personalized advisory opinions of the local therapists. The influence of local adverse factors was studied by analyzing the indicators of galvanic current and the oral hygiene index. Objectives ― to study the frequency of combination of lichen planus with somatic pathology, the level of psycho-emotional status of patients, the role of local adverse factors in the oral cavity. Methods. There were analyzed two groups of patients in the age of 24―65 years. The main group (numbered in 22 people), included patients with oral lichen planus and control group (numbered in 15 people) combined people without pathology of the oral mucosa. The main group was divided into two subgroups I (numbered in 11 people), combined patients with a typical form of oral lichen planus and subgroup II (numbered in 11 people) included patients with an erosive-ulcerative form of oral lichen planus. Clinical and laboratory examinations were conducted by a local therapist to identify somatic pathology. Filled in the “health questionnaire” and tested by the method of Zung. Determined the concentration of glucose in blood; blood pressure indicators; the level of hygiene and galvanic current. Results. Questioning showed that patients with oral lichen planus have somatic pathology. Testing according to Zung's method revealed psycho-emotional disorders. Clinical and laboratory examination by a therapist revealed 100 % somatic pathology, concentration of glucose in blood and blood pressure in most individuals exceeded WHO standards. Analysis of the hygiene index showed a low level of oral hygiene; analysis of galvanometry revealed the presence of galvanic current in the oral cavity. Conclusions. Among all patients with oral lichen planus somatic pathology was detected in 100 % of cases. Lichen planus proceeds against the background of psycho-emotional disorders. Local unfavorable factors of the oral cavity (low level of hygiene and galvanic current) aggravate the course of lichen planus, slow down the regeneration.

Keywords:
oral lichen planus, erosion of the oral mucosa, somatic pathology, diabetes, psycho-emotional status, level of hygiene
References

1. Anisimova, I. V., Nagaeva, M. O. (2017). Analiz struktury zabolevaniy slizistoy obolochki rta i krasnoy kaymy gub po obrashcheniyam patsiyentov v stomatologicheskuyu polikliniku №1 g. Omska [Analysis of the structure of diseases of the mucous membrane of the mouth and the red border of the lips according to the appeals of patients to the dental clinic No. 1 of the city of Omsk]. Innovatsionnyye tekhnologii stomatologii : materialy XXIV Mezhdunarodnogo yubileynogo simpoziuma, posvyashchonnyye 60-letiyu stomatologicheskogo fakul'teta Omskogo gosudarstvennogo meditsinskogo universiteta [Innovative technologies of dentistry: Sat. scientific Art, materials of the XXIV International Anniversary Symposium dedicated to the 60th anniversary of the Faculty of Dentistry of Omsk State Medical University], 542. (In Russ.)

2. Gileva, O. S. et al. (2017). Parodontologicheskiye aspekty zabolevaniy slizistoy obolochki polosti rta: krasnyy ploskiy lishay [Parodontological aspects of diseases of the oral mucosa: lichen planus]. Parodontologiya [Periodontology], 22, 3, 9-14. (In Russ.)

3. Gileva, O. S. et al. (2013). Predrakovyye zabolevaniya v strukture patologii slizistoy obolochki polosti rta [Precancerous diseases in the structure of the pathology of the mucous membrane of the oral cavity]. Problemy stomatologii [Actual problems in dentistry], 2, 3-9. (In Russ.)

4. Grigoryev, S. S., Zhovtyak, P. B. (2014). Otsenka somaticheskoy patologii u patsiyentov s krasnym ploskim lishayem slizistoy obolochki polosti rta [Assessment of somatic pathology in patients with red planar lichen of the oral mucosa]. Problemy stomatologii [Actual problems in dentistry], 5, 15-17. (In Russ.)

5. Lukinykh, L. M., Tiunova, N. V. (2014). Krasnyy ploskiy lishay slizistoy obolochki polosti rta [Lichen planus of the oral mucosa: a tutorial]. Nizhny Novgorod, NGMA, 81. (In Russ.)

6. Surdina, E. D. et al. (2015). Osobennosti narusheniy lipidnogo obmena u bol'nykh krasnym ploskim lishayem slizistoy obolochki rta [Peculiarities of lipid metabolic disorders in patients with lichen planus of the oral mucosa]. Vestnik Sankt-Peterburgskogo universiteta. Meditsina [Bulletin of St. Petersburg University. The medicine.], 4, 145-155. (In Russ.)

7. Surdina, E. D. et al. (2017). Otsenka mikrobioty polosti rta, tonkoy i tolstoy kishki u bol'nykh krasnym ploskim lishayem slizistoy obolochki rta [Evaluation of the microbiota of the oral cavity, the small and large intestine in patients with lichen planus of the red oral mucosa]. Parodontologiya [Periodontology], 22, 2 (83), 47-52. (In Russ.)

8. Rabinovich, O. F., Rabinovich, I. M., Abramova, E. S. (2011). Proyavleniya disbakterioza i kandidoza pri razlichnykh zabolevaniyakh slizistoy obolochki polosti rta [Manifestations of dysbacteriosis and candidiasis in various diseases of the oral mucosa]. Klinicheskaya stomatologiya [Clinical Dentistry], 3, 48-51. (In Russ.)

9. Rony, G. I, Akmalova, G. M. (2014). Rol' virusnoy infektsii v razvitii krasnogo ploskogo lishaya slizistoy obolochki polosti rta [The role of viral infection in the development of lichen planus of the oral mucosa]. Parodontologiya [Periodontology], 19, 1, 24-26. (In Russ.)

10. Khairetdinova, K. F, Yusupova, L. A. (2016). Komorbidnyye trevozhnyye i depressivnyye rasstroystva u bol'nykh krasnym ploskim lishayem s uchetom gendernykh razlichiy [Comorbid anxiety and depressive disorders in patients with lichen planus, taking into account gender differences]. Lechashchiy vrach [Leading doctor], 11, 34-38. (In Russ.)

11. Khairetdinova, K. F. (2015). Issledovaniye kliniko - immunologicheskikh i psikhologicheskikh rasstroystv bol'nykh krasnym ploskim lishayem [The study of clinical, immunological and psychological disorders of patients with lichen planus]. Aktual'nyye napravleniya nauchnykh issledovaniy: ot teorii k praktike [Actual areas of research: from theory to practice], 3 (5), 87-88. (In Russ.)

12. Anisimova, I. V. et al. (2018). Kharakteristika dannykh anketirovaniya, mikrokristallizatsii i laboratornykh pokazateley rotovoy zhidkosti u patsiyentov s krasnym ploskim lishayem [The data characteristic of the questionnaire survey, microcrystallization and laboratory indicators of oral fluid in patients with lichen planus]. Problemy stomatologii [Actual problems in dentistry], 1, 5-10. (In Russ.)

13. Khomskaya, E. D. (2014). Neyropsikhologiya [Neuropsychology: textbook for high schools]. 4, +CD, 496. (In Russ.)

14. Tsimbalistov, A. V., Robakidze, I. S. (2005). Patofiziologicheskiye aspekty razvitiya sochetannoy patologii polosti rta i zheludochno-kishechnogo trakta [Pathophysiological aspects of the development of combined pathology of the oral cavity and gastrointestinal tract]. Stomatologiya dlya vsekh [Dentistry for all], 1, 28-34. (In Russ.)

15. Chuykin, S. V., Akmalova, G. M., Chernysheva, N. D. (2014). Kharakteristika mikroflory polosti rta u bol'nykh s krasnym ploskim lishayem [Characteristic of oral microflora in patients with lichen planus]. Parodontologiya [Periodontology], 4 (73), 41-43. (In Russ.)

16. Chuikin, S. V., Akmalova, G. M., Chernysheva, N. D. (2015). Izmeneniye immunologicheskikh pokazateley virusnoy infektsii u patsiyentov s krasnym ploskim lishayem slizistoy obolochki rta [Changes in the immunological parameters of viral infection in patients with lichen planus of the oral mucosa]. Problemy stomatologii [Actual problems in dentistry], 5-6, 18-21. (In Russ.)

17. Shukurova, U. A., Bekzhanova, O. E., Arifova, N. S. (2014). Lokal'nyye faktory riska u bol'nykh s krasnym ploskim lishayem slizistoy obolochki polosti rta [Local risk factors in patients with lichen planus of the oral mucosa]. Materialy III Mezhdunarodnoy nauchno-prakticheskoy konferentsii «Neotlozhnaya pomoshch' v meditsine. Stomatologiya» [Proceedings of the III International Scientific and Practical Conference “Emergency Medical Care. Dentistry], 7-8, 53-58 (In Kazakhstan)

18. Mikhalchenko, A. V. et al. (2016). Erozivno-yazvennaya forma krasnogo ploskogo lishaya: perspektivy novogo podkhoda k terapii i prognozu [Erosive-ulcerative form of lichen planus]. Nauchnoye obozreniye. Meditsinskiye nauki [Scientific Review. Medical sciences], 3, 80-84. (In Russ.)

19. Berger, T. G. (2015). Lichen planus. JAMA Dermatol, 151, 3, 356.

20. Gonçalves, L M., Bezerra Júnior, J. R., Cruz, M. C. (2010). Clinical evaluation of oral lesions associated with dermatologic diseases. An Bras Dermatol, 85, 2, 150-156.

21. Gupta, S., Jawanda, M. K. (2015). Oral lichen planus: An update on etiology, pathogenesis, clinical presentation, diagnosis and management. Indian J Dermatol, 60, 222-229.

22. Lavanya, N., et al. (2011). Oral lichen planus: an update on pathogenesis and treatment. J Oral Maxillofacial Pathol, 15, 2, 127-132.

23. Lodi, G., Pellicano, R., Carrozzo, M. (2010). Hepatitis C virus infection and lichen planus: asystematic review with meta-analysis. Oral Dis, 16, 7, 601-612.

24. Mehdipour, M. et al. (2010). Prevalence of Candida species in erosive oral lichen planus. J Dent Res Dent Clin.Dent. Prospects, 4, 14-16.

25. Oliveira, J. et al. (2015). Esophageal lichen planus. An Bras Dermatol, 90, 3, 394-396.

26. Sandhu, S. V. et al. (2014). Oral lichen planus and stress: An appraisal. Contemp. Clin. Dent, 5, 352-356.

27. Simark-Mattsson, C., Eklund, C. (2013). Reduced immune responses to purified protein derivative and Candida albicans in oral lichen planus. J Oral Pathol Med, 42, 691-697.


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