LEVELS OF SENSITIZATION TO ALLERGENS OF FUNGAL ETIOLOGY AND THE ROLE OF LOCAL IMMUNITY IN DISEASES OF THE MUCOUS MEMBRANE OF THE ORAL CAVITY
Abstract and keywords
Abstract (English):
Predmet. Izuchenie sostoyaniya zdorov'ya lyudey Rossii, podvergayuschihsya vozdeystviyu vrednyh proizvodstvennyh faktorov v svoey trudovoy deyatel'nosti, yavlyaetsya ostroy problemoy strany. Dlitel'noe vliyanie kompleksa vrednyh proizvodstvennyh faktorov pticevodcheskogo proizvodstva, naryadu s uhudsheniem obschego sostoyaniya zdorov'ya, privodit i k ser'eznym patologiyam organov polosti rta, a imenno, k porazheniyam slizistoy obolochki rta, krasnoy kaymy gub, zabolevaniyam parodonta i tverdyh tkaney zubov. V dannoy stat'e rassmatrivaetsya patogenez i rasprostranennost' zabolevaniy slizistoy obolochki rta pri sensibilizacii slizistoy obolochki rta k gribkovym allergenam i narushenii mestnogo immuniteta polosti rta. Celi. Izuchenie urovnya sensibilizacii slizistoy obolochki rta k gribkovym allergenam po koncentracii immuno-specificheskogo IgE k Candidaalbicans i sostoyaniya mestnogo immuniteta po soderzhaniyu sICAM-1 v RZh pri takih zabolevaniyah slizistoy obolochki rta, kak recidiviruyuschiy aftoznyy stomatit, krasnyy ploskiy lishay, heylity u rabochih, imeyuschih kontakt s gribkovymi allergenami, nezavisimo ot stazha raboty. Metodologiya. V processe issledovaniya byl proveden zabor RZh i opredeleny koncentracii specificheskogo IgE k Candidaalbicans i sICAM-1. Takzhe provedeno mikroskopicheskoe issledovanie soskoba s SOR dlya postanovki diagnoza kandidoz i kandidonositel'stvo. Rezul'taty. V rezul'tate provedennogo nami issledovaniya dokazano mesto povysheniya immunospecificheskogo IgE k Candidaalbicans i znachenie mestnogo immuniteta polosti rta pri recidiviruyuschem aftoznom stomatite, krasnom ploskom lishae i heylitah u bol'shogo procenta rabochih pticefabriki. Vyvody. V rezul'tate provedennogo nami issledovaniya dokazana svyaz' sensibilizacii k gribkovym allergenam i izmeneniya mestnogo immuniteta s takimi zabolevaniyami slizistoy obolochki rta, kak hronicheskiy aftoznyy stomatit, krasnyy ploskiy lishay i heylit.

Keywords:
vrednye faktory proizvodstva, gribkovaya sensibilizaciya, mestnyy immunitet, zabolevaniya slizistoy obolochki rta
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