employee
Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Predmet. V dannoy stat'e izuchalas' vozmozhnost' primeneniya kristallograficheskogo metoda rotovoy zhidkosti v diagnostike krasnogo ploskogo lishaya (KPL) i ocenke dinamiki lecheniya. Proveden analiz anketirovaniya, testirovaniya lic s KPL, mikrokristallizacii i laboratornyh pokazateley rotovoy zhidkosti. Cel'. Pacientov osnovnoy gruppy anketirovali («anketa zdorov'ya») i testirovali (test Zunga) s cel'yu vyyavleniya nalichiya somaticheskoy patologii i urovnya psihoemocional'nogo sostoyaniya. Metodologiya. Issledovalis' dve gruppy pacientov v vozraste 24—77 let: osnovnaya (10 chelovek) s ustanovlennym diagnozom «krasnyy ploskiy lishay» (erozivno-yazvennoy formy) i kontrol'naya (10 chelovek) bez patologii slizistoy obolochki rta. V obeih gruppah u issleduemyh lic v kaple smeshannoy slyuny opredelyali tip mikrokristallizacii (MKS), po dannym kotoroy u lic kontrol'noy gruppy nami byli razrabotany otnositel'nye kriterii normy, ishodya iz kotoryh u lic osnovnoy gruppy (do lecheniya) v kaple slyuny byli vyyavleny priznaki destrukcii kristallov i kraevoy zony. V rotovoy zhidkosti opredelyali pokazateli rN, bufernoy emkosti, koncentracii obschego belka, kotorye do lecheniya ne sootvetstvovali norme. U 50 % pacientov osnovnoy gruppy bylo provedeno mikrobiologicheskoe issledovanie naleta s poverhnosti erozii. Rezul'taty. Kompleksnoe, etiopatogeneticheskoe lechenie KPL provodilos' po sheme Lukinyh L. M. s soavt. [8]. V dinamike lecheniya nablyudalis' klinicheskaya minimizaciya bolevyh oschuscheniy i tendenciya k regeneracii defektov epiteliya. Dinamika pokazateley kristallografii slyuny pokazala vosstanovlenie struktury kristallov i prozrachnosti kraevoy zony. Laboratornye parametry rN, bufernoy emkosti i obschego belka priblizilis' k normal'nym znacheniyam. Vyvody. Takim obrazom, analiz rezul'tatov anketirovaniya i testirovaniya vyyavil u lic s KPL nalichie somaticheskoy patologii i skrytuyu depressiyu. Kristallograficheskiy metod kak vspomogatel'nyy mozhno ispol'zovat' v ocenke dinamiki i effektivnosti lecheniya pacientov s krasnym ploskim lishaem. Laboratornye pokazateli (rN, bufernaya emkost', obschiy belok) mogut sluzhit' dopolnitel'nym kriteriem effektivnosti lecheniya.
krasnyy ploskiy lishay, erozii slizistoy rta, rotovaya zhidkost', kristallograficheskiy metod
1. Vavilova T. P., Yanushevich O. O., Ostrovskaya T. P. Slyuna. Analiticheskiye vozmozhnosti i perspektivy [Saliva. Analytical possibilities and prospects]. Moscow, BINOM, 2014, 312 p.
2. Vavilova T. P. Biokhimiya tkaney i zhidkostey polosti rta [Biochemistry of tissues and fluids of the oral cavity: a textbook]. 2nd ed, Moscow, 2011, 208 p.
3. Grigoryev S. S., Zhovtyak P. B. [Assessment of somatic pathology in patients with red planar lichen of the oral mucosa]. Problemy stomatologii = Dentistry problems, 2014, no. 5, pp. 15-17. (In Russ.)
4. Denisov A. B. [Algorithm for evaluating crystalline figures obtained by drying mixed saliva]. Byulleten’ eksperimental’noy biologii i meditsiny = Bulletin of Experimental Biology and Medicine, 2004, no. 7, pp. 37-40. (In Russ.)
5. Denisov A. B. [Microcrystallization of saliva: new methodological approaches]. Stomatologiya = Stomatology, 2007, vol. 86, no. 5, pp. 20-23. (In Russ.)
