THE DATA CHARACTERISTIC OF THE QUESTIONNAIRE SURVEY, MICROCRYSTALLIZATION AND LABORATORY INDICATORS OF ORAL FLUID IN PATIENTS WITH LICHEN PLANUS
Abstract and keywords
Abstract (English):
Predmet. V dannoy stat'e izuchalas' vozmozhnost' primeneniya kristallograficheskogo metoda rotovoy zhidkosti v diagnostike krasnogo ploskogo lishaya (KPL) i ocenke dinamiki lecheniya. Proveden analiz anketirovaniya, testirovaniya lic s KPL, mikrokristallizacii i laboratornyh pokazateley rotovoy zhidkosti. Cel'. Pacientov osnovnoy gruppy anketirovali («anketa zdorov'ya») i testirovali (test Zunga) s cel'yu vyyavleniya nalichiya somaticheskoy patologii i urovnya psihoemocional'nogo sostoyaniya. Metodologiya. Issledovalis' dve gruppy pacientov v vozraste 24—77 let: osnovnaya (10 chelovek) s ustanovlennym diagnozom «krasnyy ploskiy lishay» (erozivno-yazvennoy formy) i kontrol'naya (10 chelovek) bez patologii slizistoy obolochki rta. V obeih gruppah u issleduemyh lic v kaple smeshannoy slyuny opredelyali tip mikrokristallizacii (MKS), po dannym kotoroy u lic kontrol'noy gruppy nami byli razrabotany otnositel'nye kriterii normy, ishodya iz kotoryh u lic osnovnoy gruppy (do lecheniya) v kaple slyuny byli vyyavleny priznaki destrukcii kristallov i kraevoy zony. V rotovoy zhidkosti opredelyali pokazateli rN, bufernoy emkosti, koncentracii obschego belka, kotorye do lecheniya ne sootvetstvovali norme. U 50 % pacientov osnovnoy gruppy bylo provedeno mikrobiologicheskoe issledovanie naleta s poverhnosti erozii. Rezul'taty. Kompleksnoe, etiopatogeneticheskoe lechenie KPL provodilos' po sheme Lukinyh L. M. s soavt. [8]. V dinamike lecheniya nablyudalis' klinicheskaya minimizaciya bolevyh oschuscheniy i tendenciya k regeneracii defektov epiteliya. Dinamika pokazateley kristallografii slyuny pokazala vosstanovlenie struktury kristallov i prozrachnosti kraevoy zony. Laboratornye parametry rN, bufernoy emkosti i obschego belka priblizilis' k normal'nym znacheniyam. Vyvody. Takim obrazom, analiz rezul'tatov anketirovaniya i testirovaniya vyyavil u lic s KPL nalichie somaticheskoy patologii i skrytuyu depressiyu. Kristallograficheskiy metod kak vspomogatel'nyy mozhno ispol'zovat' v ocenke dinamiki i effektivnosti lecheniya pacientov s krasnym ploskim lishaem. Laboratornye pokazateli (rN, bufernaya emkost', obschiy belok) mogut sluzhit' dopolnitel'nym kriteriem effektivnosti lecheniya.

Keywords:
krasnyy ploskiy lishay, erozii slizistoy rta, rotovaya zhidkost', kristallograficheskiy metod
Text
Publication text (PDF): Read Download
References

1. Vavilova T. P., Yanushevich O. O., Ostrovskaya T. P. Slyuna. Analiticheskiye vozmozhnosti i perspektivy [Saliva. Analytical possibilities and prospects]. Moscow, BINOM, 2014, 312 p.

2. Vavilova T. P. Biokhimiya tkaney i zhidkostey polosti rta [Biochemistry of tissues and fluids of the oral cavity: a textbook]. 2nd ed, Moscow, 2011, 208 p.

3. Grigoryev S. S., Zhovtyak P. B. [Assessment of somatic pathology in patients with red planar lichen of the oral mucosa]. Problemy stomatologii = Dentistry problems, 2014, no. 5, pp. 15–17. (In Russ.)

4. Denisov A. B. [Algorithm for evaluating crystalline figures obtained by drying mixed saliva]. Byulleten’ eksperimental’noy biologii i meditsiny = Bulletin of Experimental Biology and Medicine, 2004, no. 7, pp. 37–40. (In Russ.)

5. Denisov A. B. [Microcrystallization of saliva: new methodological approaches]. Stomatologiya = Stomatology, 2007, vol. 86, no. 5, pp. 20–23. (In Russ.)