Omsk, Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Omsk, Russian Federation
Omsk, Omsk, Russian Federation
Predmet. V dannoy stat'e izuchalas' vozmozhnost' primeneniya kristallograficheskogo metoda rotovoy zhidkosti v diagnostike krasnogo ploskogo lishaya (KPL) i ocenke dinamiki lecheniya. Proveden analiz anketirovaniya, testirovaniya lic s KPL, mikrokristallizacii i laboratornyh pokazateley rotovoy zhidkosti. Cel'. Pacientov osnovnoy gruppy anketirovali («anketa zdorov'ya») i testirovali (test Zunga) s cel'yu vyyavleniya nalichiya somaticheskoy patologii i urovnya psihoemocional'nogo sostoyaniya. Metodologiya. Issledovalis' dve gruppy pacientov v vozraste 24—77 let: osnovnaya (10 chelovek) s ustanovlennym diagnozom «krasnyy ploskiy lishay» (erozivno-yazvennoy formy) i kontrol'naya (10 chelovek) bez patologii slizistoy obolochki rta. V obeih gruppah u issleduemyh lic v kaple smeshannoy slyuny opredelyali tip mikrokristallizacii (MKS), po dannym kotoroy u lic kontrol'noy gruppy nami byli razrabotany otnositel'nye kriterii normy, ishodya iz kotoryh u lic osnovnoy gruppy (do lecheniya) v kaple slyuny byli vyyavleny priznaki destrukcii kristallov i kraevoy zony. V rotovoy zhidkosti opredelyali pokazateli rN, bufernoy emkosti, koncentracii obschego belka, kotorye do lecheniya ne sootvetstvovali norme. U 50 % pacientov osnovnoy gruppy bylo provedeno mikrobiologicheskoe issledovanie naleta s poverhnosti erozii. Rezul'taty. Kompleksnoe, etiopatogeneticheskoe lechenie KPL provodilos' po sheme Lukinyh L. M. s soavt. [8]. V dinamike lecheniya nablyudalis' klinicheskaya minimizaciya bolevyh oschuscheniy i tendenciya k regeneracii defektov epiteliya. Dinamika pokazateley kristallografii slyuny pokazala vosstanovlenie struktury kristallov i prozrachnosti kraevoy zony. Laboratornye parametry rN, bufernoy emkosti i obschego belka priblizilis' k normal'nym znacheniyam. Vyvody. Takim obrazom, analiz rezul'tatov anketirovaniya i testirovaniya vyyavil u lic s KPL nalichie somaticheskoy patologii i skrytuyu depressiyu. Kristallograficheskiy metod kak vspomogatel'nyy mozhno ispol'zovat' v ocenke dinamiki i effektivnosti lecheniya pacientov s krasnym ploskim lishaem. Laboratornye pokazateli (rN, bufernaya emkost', obschiy belok) mogut sluzhit' dopolnitel'nym kriteriem effektivnosti lecheniya.
krasnyy ploskiy lishay, erozii slizistoy rta, rotovaya zhidkost', kristallograficheskiy metod
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