LOCAL IMMUNITY AND FEATURES OF THE CLINICAL COURSE OF CHRONIC GENERALIZED CATARRHAL GINGIVITIS (XGCG) ASSOCIATED WITH NEUROCIRCULATORY ASTHENIA (NCA) IN YOUNG MEN OF CONSCRIPT AGE
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Abstract (English):
Predmet. Vospalitel'nye zabolevaniya parodonta (VZP) chasto vyyavlyayutsya u yunoshey prizyvnogo vozrasta s neyrocirkulyatornoy asteniey (NCN). Pokazano, chto mestnyy immunitet VZP i NCA snizhen, odnako otsutstvuyut dannye o sostoyanii etih zabolevaniy u yunoshey prizyvnogo vozrasta. V sisteme predstavleny dannye o sostoyanii mestnoy immunnoy zaschity pri sochetanii etih zabolevaniy u yunoshey prizyvnogo vozrasta s hronicheskim generalizovannym kataral'nym gingivitom (HGKG), associirovannym s NCA. Cel'yu issledovaniya yavlyaetsya izuchenie faktorov mestnoy immunnoy zaschity u yunoshey prizyvnogo vozrasta s HGKG, associirovannym s NCA. Metodologiya. Provedeno obsledovanie 111 yunoshey prizyvnogo vozrasta (ot 18 do 21 goda), kotorye po dannym obsledovaniya razdeleny na 4 gruppy sravneniya: yunoshi s HGKG v sochetanii s NCA (28 chel.), s HGKG (22 chel.), s NCA (36 chel.) i kontrol'naya gruppa zdorovyh yunoshey (25 chel.). Issledovalis' klinicheskoe techenie HGKG (faktory vospaleniya, krovotochivosti, gigieny polosti rta), diagnostika vegetativnoy disfunkcii, mestnyy immunitet (lizocim i immunoglobuliny slyuny). Rezul'taty. Provedennye issledovaniya pokazali, chto papillyarno-marginal'no-al'veolyarnyy indeks, indeksy krovotochivosti i gigieny s vysokoy stepen'yu dostovernosti povysheny u yunoshey s HGKG v sochetanii s NCA (r<0,01), pri etom chistota tyazhelogo techeniya HGKG takzhe chasche imeet mesto v etoy gruppe. Pri issledovanii mestnogo immuniteta polosti rta v gruppe yunoshey s HGKG, associirovannym s NCA, vyyavleny snizhenie aktivnosti lizocima i povyshenie immunoglobulina po sravneniyu s gruppami sravneniya, chto svidetel'stvuet o snizhenii gumoral'noy zaschity polosti rta. Vyvody. Vospalitel'nye zabolevaniya parodonta (HGKG) u yunoshey prizyvnogo vozrasta s NCA protekayut bolee tyazhelo, s vyrazhennoy vospalitel'noy reakciey, povyshennoy krovotochivost'yu i narusheniyami gigieny rotovoy polosti po sravneniyu s bol'nymi v otdel'no vzyatyh gruppah s HGKG i NCA. V osnove tyazhelogo techeniya HGKG u yunoshey prizyvnogo vozrasta s NCA lezhit vegetativnaya disfunkciya, kotoraya soprovozhdaetsya snizheniem aktivnosti lizocima s kompensatornym uvelicheniem immunoglobulinov rotovoy zhidkosti.

Keywords:
vospalitel'nye zabolevaniya parodonta, vegetativnaya disfunkciya, mestnyy immunitet
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