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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">6a9c166a32807fdbab874b5b</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-2026-22-3-20-25</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ТЕРАПЕВТИЧЕСКАЯ СТОМАТОЛОГИЯ. ОБЗОРЫ ЛИТЕРАТУРЫ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>TERAPEUTIC DENTISTRY. REVIEWS</subject>
    </subj-group>
    <subj-group>
     <subject>ТЕРАПЕВТИЧЕСКАЯ СТОМАТОЛОГИЯ. ОБЗОРЫ ЛИТЕРАТУРЫ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">A MODERN APPROACH TO THE TREATMENT OF CHRONIC RECURRENT APHTHOUS STOMATITIS</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>СОВРЕМЕННЫЙ ПОДХОД К ТЕРАПИИ ХРОНИЧЕСКОГО РЕЦИДИВИРУЮЩЕГО АФТОЗНОГО СТОМАТИТА</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Григорьев</surname>
       <given-names>Сергей Сергеевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Griroriev</surname>
       <given-names>Sergey Sergeevich</given-names>
      </name>
     </name-alternatives>
     <email>sergeygrig28@gmail.com</email>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гайнетдинов</surname>
       <given-names>Максим Ринатович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Gainetdinov</surname>
       <given-names>Maksim Rinatovich</given-names>
      </name>
     </name-alternatives>
     <email>maxim.gai0000@gmail.com</email>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Плотников</surname>
       <given-names>Александр Сергеевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Plotnikov</surname>
       <given-names>Aleksandr S.</given-names>
      </name>
     </name-alternatives>
     <email>alexplotnikov96@list.ru</email>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Козьменко</surname>
       <given-names>Анастасия Николаевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kozmenko</surname>
       <given-names>Anastasia Nikolaevna</given-names>
      </name>
     </name-alternatives>
     <email>power2030@yandex.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Торшина</surname>
       <given-names>Виктория Андреевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Torshina</surname>
       <given-names>Viktoria A.</given-names>
      </name>
     </name-alternatives>
     <email>viktoriya-torshina@mail.ru</email>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Морозов</surname>
       <given-names>Игорь Владимирович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Morozov</surname>
       <given-names>Igor V.</given-names>
      </name>
     </name-alternatives>
     <email>morozovigorvladimirovic@gmail.com</email>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Уральский государственный медицинский университет</institution>
     <city xml:lang="ru">Екатеринбург</city>
    </aff>
    <aff>
     <institution xml:lang="en">Ural State Medical University</institution>
     <city xml:lang="en">Ekaterinburg</city>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Уральский государственный медицинский университет</institution>
     <city xml:lang="ru">Екатеринбург</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Ural State Medical University</institution>
     <city xml:lang="en">Yekaterinburg</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Уральский государственный медицинский университет</institution>
     <city xml:lang="ru">Екатеринбург</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Ural State Medical University</institution>
     <city xml:lang="en">Yekaterinburg</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Уральский государственный медицинский университет</institution>
     <city xml:lang="ru">Екатеринбург</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Ural State Medical University</institution>
     <city xml:lang="en">Ekaterinburg</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Уральский государственный медицинский университет</institution>
     <city xml:lang="ru">Екатеринбург</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Ural State Medical University</institution>
     <city xml:lang="en">Ekaterinburg</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2026-09-23T23:06:12+03:00">
    <day>23</day>
    <month>09</month>
    <year>2026</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-09-23T23:06:12+03:00">
    <day>23</day>
    <month>09</month>
    <year>2026</year>
   </pub-date>
   <volume>22</volume>
   <issue>3</issue>
   <fpage>20</fpage>
   <lpage>25</lpage>
   <history>
    <date date-type="received" iso-8601-date="2026-06-29T00:00:00+03:00">
     <day>29</day>
     <month>06</month>
     <year>2026</year>
    </date>
   </history>
   <permissions>
    <copyright-statement xml:lang="ru">© 2026 Григорьев С.С., Гайнетдинов М.Р., Плотников А.С., Козьменко А.Н., Торшина В.А., Морозов И.В. Все права защищены.</copyright-statement>
    <copyright-statement xml:lang="en">© 2026 Griroriev S.S., Gainetdinov M.R., Plotnikov A.S., Kozmenko A.N., Torshina V.A., Morozov I.V. All rights reserved.</copyright-statement>
    <copyright-year>2026</copyright-year>
    <copyright-holder xml:lang="ru">Григорьев Сергей Сергеевич, Гайнетдинов Максим Ринатович, Плотников Александр Сергеевич, Козьменко Анастасия Николаевна, Торшина Виктория Андреевна, Морозов Игорь Владимирович</copyright-holder>
    <copyright-holder xml:lang="en">Griroriev Sergey Sergeevich, Gainetdinov Maksim Rinatovich, Plotnikov Aleksandr S., Kozmenko Anastasia Nikolaevna, Torshina Viktoria A., Morozov Igor V.</copyright-holder>
   </permissions>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/publications/6a9c166a32807fdbab874b5b/view">https://dental-press.ru/en/nauka/publications/6a9c166a32807fdbab874b5b/view</self-uri>
   <abstract xml:lang="ru">
    <p>Хронический рецидивирующий афтозный стоматит (ХРАС) является одним из самых распространенных заболеваний слизистой оболочки полости рта.&#13;
Цель – анализ основных современных концепций и подходов к терапии хронического рецидивирующего афтозного стоматита.&#13;
Материалы и методы. Исследование проведено на основе поиска и изучения оригинальных статей в отношении этиологии и лечения хронического рецидивирующего афтозного стоматита в базах данных PubMed, eLibrary, Google Scholar, Cyberleninka. Отбор материалов осуществлялся по ключевым словам.&#13;
Результаты. В обзоре литературы представлены современные представления об этиологии и различных методах лечения хронического рецидивирующего афтозного стоматита. Литературный обзор продемонстрировал, что наибольший доказательный вес в лечении хронического рецидивирующего афтозного стоматита имеют местные кортикостероиды, антибактериальные препараты и лазерная терапия. Для гиалуроновой кислоты, витаминно-минеральных комплексов и ряда других немедикаментозных методов в изученных исследованиях представлены менее выраженные положительные эффекты, а достоверность полученных данных находится на среднем уровне ввиду гетерогенности исследований.&#13;
Выводы. Изученные литературные данные свидетельствуют об отсутствии однозначного этиологического фактора в развитии хронического рецидивирующего афтозного стоматита. По этой причине лечение хронического рецидивирующего афтозного стоматита базируется в основном на симптоматической помощи, что подразумевает устранение предрасполагающих факторов и местную терапию. Наиболее изученными препаратами для лечения хронического рецидивирующего афтозного стоматита являются местные кортикостероиды и низкоинтенсивная лазерная терапия, оказывающие более выраженный анальгезирующий и регенеративный эффект по сравнению с прочими препаратами. Однако, отсутствие единых протоколов лечения обусловливает необходимость дальнейших клинических исследований.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Chronic recurrent aphthous stomatitis (CRAS) is one of the most common diseases of the oral mucosa.&#13;
The aim of this study is to analyze the main modern concepts and approaches to the treatment of chronic recurrent aphthous stomatitis.&#13;
Materials and methods. The study was conducted by searching and reviewing original articles on the etiology and treatment of chronic recurrent aphthous stomatitis in the PubMed, eLibrary, Google Scholar, and Cyberleninka databases. Materials were selected using keywords.&#13;
Results. This literature review presents current understanding of the etiology and various treatment methods for chronic recurrent aphthous stomatitis. The literature review demonstrated that topical corticosteroids, antibacterial agents, and laser therapy have the greatest weight of evidence in the treatment of chronic recurrent aphthous stomatitis. For hyaluronic acid, vitamin-mineral supplements, and a number of other non-drug treatments, the studies reviewed demonstrated less pronounced positive effects, and the reliability of the data obtained was moderate due to the heterogeneity of the studies.&#13;
Conclusions. The literature reviewed indicates the absence of a definitive etiologic factor in the development of chronic recurrent aphthous stomatitis. For this reason, treatment for chronic recurrent aphthous stomatitis relies primarily on symptomatic management, which involves eliminating predisposing factors and topical therapy. The most studied medications for the treatment of chronic recurrent aphthous stomatitis are topical corticosteroids and low-level laser therapy, which have a more pronounced analgesic and regenerative effect than other medications. However, the lack of uniform treatment protocols necessitates further clinical trials.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>хронический рецидивирующий афтозный стоматит</kwd>
    <kwd>этиология</kwd>
    <kwd>лечение</kwd>
    <kwd>гиалуроновая кислота</kwd>
    <kwd>кортикостероиды</kwd>
    <kwd>лазеротерапия</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>chronic recurrent aphthous stomatitis</kwd>
    <kwd>etiology</kwd>
    <kwd>treatment</kwd>
    <kwd>hyaluronic acid</kwd>
    <kwd>corticosteroids</kwd>
    <kwd>laser therapy</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
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