The relevance of the problem of dental morbidity in children is obvious. In 2022, an epidemiological survey of the main dental diseases of the child population was conducted according to the WHO methodology in Ekaterinburg and the Sverdlovsk region in key groups of 3, 6, 12 and 15 years old. The epidemiological survey involved 756 children in six settlements of the region. The registration of the oral cavity condition was carried out using the "Maps for assessing the dental status of children" recommended by the World Health Organization (2013). Informed consent was obtained from parents and guardians to participate in the survey. Statistical processing of the results was carried out in the Statistica 10 program. In Yekaterinburg and the Sverdlovsk region, dental caries and inflammatory periodontal diseases remain the most common pathology in children. The prevalence of caries in 3, 6, 12, 15-year-olds was 34,2%, 80%, 20%, 86%, 96% accordingly , at an intensity of 2,3±0,5; 4,9±0,2; 4,59±0,3; 6,5±0,4. Signs of periodontal inflammation were detected among 12-year-olds in Yekaterinburg in 35.2% children, in the region - 38.1% of children. Among 15-year-olds, this indicator was 24.0% and 48.8%. These indicators increased with age. The prevalence of enamel hypoplasia in the main key group of 12-year-olds in Ekaterinburg was 8%, in the region – 12,9%. 90% of children need fissure sealing of permanent molars. In comparison with the previously conducted national epidemiological surveys of 2008 and 2015, there is an unfavorable dynamics and deterioration of the main indicators of dental morbidity. The epidemiological survey conducted in Ekaterinburg and the cities of the Sverdlovsk region is the justification for the development and implementation of a regional program for the prevention of dental diseases.