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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">52322</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-2022-18-2-23-28</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ЛЕКЦИИ / ЛИТЕРАТУРНЫЕ ОБЗОРЫ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>LITERATURE REVIEW</subject>
    </subj-group>
    <subj-group>
     <subject>ЛЕКЦИИ / ЛИТЕРАТУРНЫЕ ОБЗОРЫ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">ANOMALIES IN THE DEVELOPMENT AND DEFORMATION OF THE FORM OF THE TEETH: THE ETIOLOGICAL ROLE OF GENETIC, EPIGENETIC AND ENVIRONMENTAL FACTORS (LITERATURE REVIEW)</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>АНОМАЛИИ РАЗВИТИЯ И ДЕФОРМАЦИИ ФОРМЫ ЗУБОВ: ЭТИОЛОГИЧЕСКАЯ РОЛЬ ГЕНЕТИЧЕСКИХ, ЭПИГЕНЕТИЧЕСКИХ И ЭКОЛОГИЧЕСКИХ ФАКТОРОВ (ОБЗОР ЛИТЕРАТУРЫ)</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Погадаев</surname>
       <given-names>Дмитрий Владимирович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Pogadaev</surname>
       <given-names>Dmitriy Vladimirovich</given-names>
      </name>
     </name-alternatives>
     <email>fake@neicon.ru</email>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Омский государственный медицинский университет</institution>
     <city>Омск</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Omsk State Medical University</institution>
     <city>Omsk</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2022-08-18T21:16:26+03:00">
    <day>18</day>
    <month>08</month>
    <year>2022</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2022-08-18T21:16:26+03:00">
    <day>18</day>
    <month>08</month>
    <year>2022</year>
   </pub-date>
   <volume>18</volume>
   <issue>2</issue>
   <fpage>23</fpage>
   <lpage>28</lpage>
   <history>
    <date date-type="received" iso-8601-date="2022-08-07T00:00:00+03:00">
     <day>07</day>
     <month>08</month>
     <year>2022</year>
    </date>
   </history>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/article/52322/view">https://dental-press.ru/en/nauka/article/52322/view</self-uri>
   <abstract xml:lang="ru">
    <p>Предмет исследования — зубы, аномалии развития форм.&#13;
Цель — провести анализ литературных данных по изучению морфофункциональных параметров зубов в эволюционном аспекте.&#13;
Методология. Поиск публикаций в научно-медицинской библиотеке ОмГМУ, на внешних базах данных Elibrary, Cyberleninka, PubMed, Embase. Проведен обзор 33 литературных источников за период 2012–2022 гг. (16 отечественных источников, 17 зарубежных). Полученная информация обработана, систематизирована и оформлена в текстовом формате.&#13;
Результаты. Большинство аномалий и деформаций форм зубов имеют полиэтиологическую природу. Сложное влияние и взаимодействие генетических, эпигенетических и средовых факторов приводит к нарушению формы, функции и эстетики зубов. Процесс возникновения аномалий зубов является многоуровневым, многомерным и прогрессивным. К изменению формы зубов приводят и патологические процессы, связанные с утратой твердых тканей зуба в течение жизни человека. Так, например, кариес является одним из самых распространенных стоматологических заболеваний. Установлено, что кариес зубов (КЗ) — это инфекционный процесс, возникающий под влиянием нескольких групп факторов. По данным ВОЗ, заболеваемость кариесом зубов колеблется от 80 до 98%, что свидетельствует о необходимости широкого внедрения программ профилактики среди всех возрастных групп.&#13;
Выводы. Необходимо проведение междисциплинарных исследований для преодоления разрыва между пониманием молекулярных событий, происходящих в период одонтогенеза, и сутью клинических наблюдений, характеризующих степень изменчивости формы зубов под действием генетических, экологических и эпигенетических факторов.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>The subject of the study: teeth, anomalies in the development of forms.&#13;
The purpose of the study: to analyze the literature data on the study of the morphofunctional parameters of teeth in the evolutionary aspect.&#13;
Methodology. Search for publications in the scientific and medical library of Omsk State Medical University, on external databases Elibrary, Cyberleninka, PubMed, Embase. Review of 33 literary sources has been carried out for the period 2012–2022 (16 domestic, 17 foreign). The received information is processed, systematized and presented in text format.&#13;
The results: Most anomalies and deformations of the shape of the teeth are polyetiological in nature. The complex influence and interaction of genetic, epigenetic and environmental factors leads to a violation of the form. function and aesthetics of teeth. The process of occurrence of dental anomalies is multilevel, multidimensional and progressive. Pathological processes associated with the loss of hard tooth tissues during a person's life also lead to a change in the shape of the teeth. For example, caries is one of the most common dental diseases. It has been established that dental caries is an infectious process that occurs under the influence of several groups of factors. According to the World Health Organization, the incidence of dental caries ranges from 80% to 98%, which indicates the need for widespread implementation of prevention programs among all age groups.&#13;
Conclusion. It is necessary to conduct interdisciplinary research to bridge the gap between understanding the molecular events that occur during odontogenesis and the essence of clinical observations characterizing the degree of variability in the shape, size, defects of teeth (anomalies, deformities, lesions) under the influence of genetic, environmental and epigenetic factors.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>зубы</kwd>
    <kwd>аномалии развития</kwd>
    <kwd>одонтогенез</kwd>
    <kwd>генетический фактор</kwd>
    <kwd>экологический фактор</kwd>
    <kwd>кариес</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>teeth</kwd>
    <kwd>developmental anomalies</kwd>
    <kwd>odontogenesis</kwd>
    <kwd>genetic factor</kwd>
    <kwd>environmental factor</kwd>
    <kwd>caries</kwd>
   </kwd-group>
  </article-meta>
 </front>
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  <p></p>
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