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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">46771</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-21-17-3-58-63</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ПАРОДОНТОЛОГИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>PERIODONTIC DENTISTRY</subject>
    </subj-group>
    <subj-group>
     <subject>ПАРОДОНТОЛОГИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">FEATURES OF THE CLINICAL STATE OF PERIODONTAL TISSUES IN YOUNG PEOPLE</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ОСОБЕННОСТИ КЛИНИЧЕСКОГО СОСТОЯНИЯ ТКАНЕЙ ПАРОДОНТА У ЛИЦ МОЛОДОГО ВОЗРАСТА</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Усманова</surname>
       <given-names>Ирина Николаевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Usmanova</surname>
       <given-names>Irina N.</given-names>
      </name>
     </name-alternatives>
     <email>irinausmanova@mail.ru</email>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Аль Кофиш</surname>
       <given-names>Moхаммед Али Мохаммед </given-names>
      </name>
      <name xml:lang="en">
       <surname>Al-Qufaish</surname>
       <given-names>M.A.M. </given-names>
      </name>
     </name-alternatives>
     <email>alqufaesh@gmail.com</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Кузнецова</surname>
       <given-names>Лилия Ильинична</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kuznetsova</surname>
       <given-names>Lilia I.</given-names>
      </name>
     </name-alternatives>
     <email>89177859529@mail.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Шангареева</surname>
       <given-names>Алия Ирековна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Shangareeva</surname>
       <given-names>Alia Irekovna</given-names>
      </name>
     </name-alternatives>
     <email>180780_lena@mail.ru</email>
     <xref ref-type="aff" rid="aff-4"/>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Кашина</surname>
       <given-names>София Мидхатовна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kashina</surname>
       <given-names>Sofia M.</given-names>
      </name>
     </name-alternatives>
     <email>sofaufa@mail.ru</email>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Усманов</surname>
       <given-names>Ирек Рамимович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Usmanov</surname>
       <given-names>Irek Ramimovich</given-names>
      </name>
     </name-alternatives>
     <email>irek.usmanov.62@mail.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-7"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Ткаченко</surname>
       <given-names>Елена Валентиновна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Tkachenko</surname>
       <given-names>Elena V.</given-names>
      </name>
     </name-alternatives>
     <email>liguria2007@yandex.ru</email>
     <xref ref-type="aff" rid="aff-8"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Осипенко</surname>
       <given-names>Альбина Галимовна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Osipenko</surname>
       <given-names>Albina Galimovna</given-names>
      </name>
     </name-alternatives>
     <email>albinaos@bk.ru</email>
     <xref ref-type="aff" rid="aff-9"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Башкирский государственный медицинский университет</institution>
    </aff>
    <aff>
     <institution xml:lang="en">Bashkirian State Medical University</institution>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Университет г. Аден</institution>
     <city>Аден</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">University of Aden</institution>
     <city>Aden</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Башкирский государственный медицинский университет</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Bashkir State Medical Universitey</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Башкирский государственный медицинский университет</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Bashkir State Medical Universitey</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Стоматологическая клиника «КРЕМЛдента»</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Dental clinic “KREMLdenta”</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Стоматологическая поликлиника № 4</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Dental clinic number 4</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">ФГБОУ ВО &quot;Башкирский государственный медицинский университет&quot; Минздрава России</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Bashkir State Medical Universitey</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-8">
    <aff>
     <institution xml:lang="ru">Стоматологическая поликлиника № 2</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Dental clinic number 2</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-9">
    <aff>
     <institution xml:lang="ru">Стоматологическая поликлиника № 4</institution>
     <city>Уфа</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Dental clinic number 4</institution>
     <city>Ufa</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <volume>17</volume>
   <issue>3</issue>
   <fpage>58</fpage>
   <lpage>63</lpage>
   <history>
    <date date-type="received" iso-8601-date="2021-11-04T00:00:00+03:00">
     <day>04</day>
     <month>11</month>
     <year>2021</year>
    </date>
   </history>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/article/46771/view">https://dental-press.ru/en/nauka/article/46771/view</self-uri>
   <abstract xml:lang="ru">
    <p>Актуальность. Авторами установлено, что различные факторы риска играют ведущую роль в изменении клинического состояния тканей пародонта. Цель исследования — сравнительная оценка клинического состояния тканей пародонта на основании корреляции гигиенических и пародонтальных индексов в зависимости от возраста. Материал и методы. Проведено комплексное клиническое обследование 765 лиц молодого возраста. Основную группу составили 70 (66,6%) пациентов с диагностированным хроническим гингивитом и 145 (33,35%) пациентов с начальным пародонтитом легкой степени тяжести, обусловленными наличием в составе микробной биопленки условно-патогенных и пародонтопатогенных видов микроорганизмов. Контрольную группу составили 83 пациента, индексная оценка которых выявила состояние тканей пародонта в виде клинически здоровой десны с интактным пародонтом и клинически здоровой десны с потерей тканей пародонта соответственно в 61,4 и 38,6% случаев наблюдения. Результаты исследования. У 61,4% лиц, образующих группы с клинически здоровыми деснами, гигиенические и пародонтальные показатели находятся в пределах нормы, а у 38,6% лиц наблюдается тенденция к отклонению от нормы. В 47,7 и 52,3% случаев у лиц с гингивитом и в 48,3 и 51,7% у лиц с начальным пародонтитом индекс OHI-S коррелирует с показателями РМА, GI и SBI (p &lt; 0,001, р = 0,315). &#13;
Выводы. Выявленные изменения показателей гигиенических и пародонтальных индексов (коэффициент сопряженности Чупрова 0,64 (р = 0,012), критерий Краскела-Уоллиса (Н = 7,89, р &lt; 0,05) дают возможность четкого определения клинического состояния тканей пародонта, соответствующего современным европейским критериям.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Relevance of the research topic. The authors found that various risk factors play a leading role in changing the clinical state of periodontal tissues. The aim is a comparative assessment of the clinical condition of periodontal tissues based on the correlation of hygienic and periodontal indices depending on age. Material and methods. A comprehensive clinical examination of 765 young people was conducted. The main group consisted of 70 (66.6%) patients with diagnosed chronic gingivitis and 145 (33.35%) patients with mild initial periodontitis due to the presence of conditionally pathogenic and periodontopathogenic types of microorganisms in the microbial biofilm. The control group was formed by 83 patients whose index evaluation revealed the condition of periodontal tissues in the form of clinically healthy gums with intact periodontal and clinically healthy gums with periodontal tissue loss, respectively, in 61.4 and 38.6% of cases of observations. Study results. In 61.4% of persons forming groups with clinically healthy gums, hygienic and periodontal indices are within normal values, in 38.6% of cases of persons there is a tendency to change them from the norm. In 47.7% and 52.3% of cases of individuals with gingivitis and in 48.3% and 51.7% of individuals with initial periodontitis, the OHI-S index correlates with the indicators of PMA, GI and SBI (p &lt; 0.001, p = 0.315).&#13;
Conclusions. Thus, the revealed changes in the indicators of hygienic and periodontal indices (the Chuprov conjugacy coefficient is 0.64 (p = 0.012), the Kraskel-Wallis criterion (H = 7.89, p &lt; 0.05) makes it possible to clearly determine the clinical condition of periodontal tissues corresponding to modern European criteria.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>гигиенические и пародонтальные индексы</kwd>
    <kwd>клинически здоровая десна</kwd>
    <kwd>хронический гингивит</kwd>
    <kwd>начальный пародонтит</kwd>
    <kwd>молодой возраст</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>hygienic</kwd>
    <kwd>periodontal indices</kwd>
    <kwd>clinically healthy gums</kwd>
    <kwd>chronic gingivitis</kwd>
    <kwd>initial periodontitis</kwd>
    <kwd>young age</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
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 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Белоклицкая Г.Ф., Горголь К.О. Ведущие местные факторы риска в развитии воспалительных заболеваний пародонта у лиц молодого возраста. Стоматология. Эстетика. Инновации. 2017;1;2:203-214. [G.F. Biloklytska, K.O. Gorgol. The leading local risk factors in the development of inflammatory periodontal diseases in young people. Dentistry. Aesthetics. Innovations. 2017;1;2:203-214. (In Russ.)]. https://elibrary.ru/item.asp?id=32325352</mixed-citation>
     <mixed-citation xml:lang="en">Beloklickaya G.F., Gorgol' K.O. Veduschie mestnye faktory riska v razvitii vospalitel'nyh zabolevaniy parodonta u lic molodogo vozrasta. Stomatologiya. Estetika. Innovacii. 2017;1;2:203-214. [G.F. Biloklytska, K.O. Gorgol. The leading local risk factors in the development of inflammatory periodontal diseases in young people. Dentistry. Aesthetics. Innovations. 2017;1;2:203-214. (In Russ.)]. https://elibrary.ru/item.asp?id=32325352</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Усманова И.Н., Аль-Кофиш М.А., Лебедева А.И., Хуснаризанова Р.Ф., Усманов И.Р. Влияние микрофлоры полости рта на состояние микроциркуляции тканей пародонта. Уральский медицинский журнал. 2017;7(151):31-35. [I.N. Usmanova, M.A.M. Al-Kofish, A.I. Lebedeva, R.F. Kusnarizanova, I.R. Usmanov. The influence of the microflora of the mouth on the microcirculation of the periodontal tissues. Ural Medical Journal. 2017;7(151):31-35 (In Russ.)]. https://elibrary.ru/item.asp?id=30022797</mixed-citation>
     <mixed-citation xml:lang="en">Usmanova I.N., Al'-Kofish M.A., Lebedeva A.I., Husnarizanova R.F., Usmanov I.R. Vliyanie mikroflory polosti rta na sostoyanie mikrocirkulyacii tkaney parodonta. Ural'skiy medicinskiy zhurnal. 2017;7(151):31-35. [I.N. Usmanova, M.A.M. Al-Kofish, A.I. Lebedeva, R.F. Kusnarizanova, I.R. Usmanov. The influence of the microflora of the mouth on the microcirculation of the periodontal tissues. Ural Medical Journal. 2017;7(151):31-35 (In Russ.)]. https://elibrary.ru/item.asp?id=30022797</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Ланг Н.П., Бартольд М.П. Здоровый пародонт. Пародонтология. 2019;2(24):187-192. [N.P. Lang, M.P. Bartold. Periodontal health. Periodontology. 2019;2(24):187-192. (In Russ.)]. https://elibrary.ru/item.asp?id=39195270</mixed-citation>
     <mixed-citation xml:lang="en">Lang N.P., Bartol'd M.P. Zdorovyy parodont. Parodontologiya. 2019;2(24):187-192. [N.P. Lang, M.P. Bartold. Periodontal health. Periodontology. 2019;2(24):187-192. (In Russ.)]. https://elibrary.ru/item.asp?id=39195270</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Кудрявцева Т.В., Тачалов В.В., Лобода Е.С., Орехова Л.Ю., Нечай Е.Ю., Шаламай Л.И. Изучение приверженности пациентов стоматологической клиники к соблюдению профилактических мероприятий в полости рта. Пародонтология. 2019;24(2):167-172. [T.V. Kudryavtseva, V.V. Tachalov, E.S. Loboda, L.Yu. Orekhova, E.Yu. Nechai, L.I. Shalamay. Surveying adherence of dental clinic patients to preventive measures in oral cavity. Periodontology. 2019;24(2):167-172. (In Russ.)]. https://elibrary.ru/item.asp?id=39195263</mixed-citation>
     <mixed-citation xml:lang="en">Kudryavceva T.V., Tachalov V.V., Loboda E.S., Orehova L.Yu., Nechay E.Yu., Shalamay L.I. Izuchenie priverzhennosti pacientov stomatologicheskoy kliniki k soblyudeniyu profilakticheskih meropriyatiy v polosti rta. Parodontologiya. 2019;24(2):167-172. [T.V. Kudryavtseva, V.V. Tachalov, E.S. Loboda, L.Yu. Orekhova, E.Yu. Nechai, L.I. Shalamay. Surveying adherence of dental clinic patients to preventive measures in oral cavity. Periodontology. 2019;24(2):167-172. (In Russ.)]. https://elibrary.ru/item.asp?id=39195263</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Усманова И.Н., Кабирова М.Ф., Исламова Г.В., Ахмадуллин З.Т. Индексная оценка состояния гигиены полости рта у лиц молодого возраста. Здоровье, демография, экология финно-угорских народов. 2015;3:31-32. [I.N. Usmanova, M.F. Kabirova, G.V. Islamova, Z.T. Akhmadullin. Oral Hygiene Evaluation In Young Adults. Health, demography, ecology of the finno-ugric peoples. 2015;3:31-32. (In Russ.)]. https://elibrary.ru/item.asp?id=25011052</mixed-citation>
     <mixed-citation xml:lang="en">Usmanova I.N., Kabirova M.F., Islamova G.V., Ahmadullin Z.T. Indeksnaya ocenka sostoyaniya gigieny polosti rta u lic molodogo vozrasta. Zdorov'e, demografiya, ekologiya finno-ugorskih narodov. 2015;3:31-32. [I.N. Usmanova, M.F. Kabirova, G.V. Islamova, Z.T. Akhmadullin. Oral Hygiene Evaluation In Young Adults. Health, demography, ecology of the finno-ugric peoples. 2015;3:31-32. (In Russ.)]. https://elibrary.ru/item.asp?id=25011052</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Модина Т.Н., Мамаева Е.В. Клиника, диагностика патологии тканей пародонта и особенности функционального состояния организма с учетом их взаимовлияния у детей в подростковом периоде (обзор литературы). Пародонтология. 2006;4(41):6-11. [T.N. Modina, E.V. Mamaeva. Clinic and diagnostics of periodontal tissues pathology and feature of function condition of an organism in view of them influence at children in the teenage period (review of literature). Periodontitis. 2006;4(41):6-11. (In Russ.)]. https://elibrary.ru/item.asp?id=9571491</mixed-citation>
     <mixed-citation xml:lang="en">Modina T.N., Mamaeva E.V. Klinika, diagnostika patologii tkaney parodonta i osobennosti funkcional'nogo sostoyaniya organizma s uchetom ih vzaimovliyaniya u detey v podrostkovom periode (obzor literatury). Parodontologiya. 2006;4(41):6-11. [T.N. Modina, E.V. Mamaeva. Clinic and diagnostics of periodontal tissues pathology and feature of function condition of an organism in view of them influence at children in the teenage period (review of literature). Periodontitis. 2006;4(41):6-11. (In Russ.)]. https://elibrary.ru/item.asp?id=9571491</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Лукичев М.М., Ермолаева Л.А. Современные представления о роли микрофлоры в патогенезе заболеваний пародонта. Институт стоматологии. 2018;1(78):92-94. [M.M. Lukichev, L.A. Ermolaeva. Modern ideas about therole of microflora in the pathogenesis of periodontal diseases. Institute of Dentistry. 2018;1(78):92-94. (In Russ.)]. https://www.elibrary.ru/item.asp?id=34964799</mixed-citation>
     <mixed-citation xml:lang="en">Lukichev M.M., Ermolaeva L.A. Sovremennye predstavleniya o roli mikroflory v patogeneze zabolevaniy parodonta. Institut stomatologii. 2018;1(78):92-94. [M.M. Lukichev, L.A. Ermolaeva. Modern ideas about therole of microflora in the pathogenesis of periodontal diseases. Institute of Dentistry. 2018;1(78):92-94. (In Russ.)]. https://www.elibrary.ru/item.asp?id=34964799</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Цепов Л.М., Николаев А.И., Наконечный Д.А., Нестерова М.М. Микробные биопленки и хронические воспалительные заболевания пародонта (обзор литературы). Пародонтология. 2015;3(76):3-6. [L.M. Tsepov, A.I. Nikolaev, D.A. Nakonechnyi, M.M. Nesterova. Microbial biofilms and chronic inflammatory periodontal diseases (a review of the literature). Periodontology. 2015;3(76):3-6. (In Russ.)]. https://elibrary.ru/item.asp?id=2436562411</mixed-citation>
     <mixed-citation xml:lang="en">Cepov L.M., Nikolaev A.I., Nakonechnyy D.A., Nesterova M.M. Mikrobnye bioplenki i hronicheskie vospalitel'nye zabolevaniya parodonta (obzor literatury). Parodontologiya. 2015;3(76):3-6. [L.M. Tsepov, A.I. Nikolaev, D.A. Nakonechnyi, M.M. Nesterova. Microbial biofilms and chronic inflammatory periodontal diseases (a review of the literature). Periodontology. 2015;3(76):3-6. (In Russ.)]. https://elibrary.ru/item.asp?id=2436562411</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Аль-кофиш М.А.М. Оптимизация ранней диагностики, профилактики и лечения воспалительных заболеваний пародонта у лиц молодого возраста : дисс. ... канд. мед. наук. Башкирский государственный медицинский университет. Уфа, 2019:151. [M.A.M. Al-Qufaish. Optimization of early diagnosis, prevention and treatment of inflammatory periodontal diseases in young people: diss. ... cand. med. sciences. Bashkir State Medical University. Ufa, 2019:151. (In Russ.)]. https://elibrary.ru/item.asp?id=41521324</mixed-citation>
     <mixed-citation xml:lang="en">Al'-kofish M.A.M. Optimizaciya ranney diagnostiki, profilaktiki i lecheniya vospalitel'nyh zabolevaniy parodonta u lic molodogo vozrasta : diss. ... kand. med. nauk. Bashkirskiy gosudarstvennyy medicinskiy universitet. Ufa, 2019:151. [M.A.M. Al-Qufaish. Optimization of early diagnosis, prevention and treatment of inflammatory periodontal diseases in young people: diss. ... cand. med. sciences. Bashkir State Medical University. Ufa, 2019:151. (In Russ.)]. https://elibrary.ru/item.asp?id=41521324</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Орехова Л.Ю., Кудрявцева Т.В., Чеминава Н.Р., Тачалов В.В., Лобода Е.С. Проблемы стоматологического здоровья у лиц молодого возраста (обзор литературы). Пародонтология. 2014;2(71):3-5. [L.Yu. Orekhova, T.V. Kudryavtseva, N.R. Cheminava, V.V. Tachalov, E.S. Loboda. Oral health problems for young adults (review). Periodontology. 2014;2(71):3-5. (In Russ.)]. https://elibrary.ru/item.asp?id=22135425</mixed-citation>
     <mixed-citation xml:lang="en">Orehova L.Yu., Kudryavceva T.V., Cheminava N.R., Tachalov V.V., Loboda E.S. Problemy stomatologicheskogo zdorov'ya u lic molodogo vozrasta (obzor literatury). Parodontologiya. 2014;2(71):3-5. [L.Yu. Orekhova, T.V. Kudryavtseva, N.R. Cheminava, V.V. Tachalov, E.S. Loboda. Oral health problems for young adults (review). Periodontology. 2014;2(71):3-5. (In Russ.)]. https://elibrary.ru/item.asp?id=22135425</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Аль-Кофиш М.А.М., Усманова И.Н., Усманов И.Р., Хуснаризанова Р.Ф., Галиаскаров Н.Д. Оценка состояния стоматологического статуса лиц молодого возраста. Уральский медицинский журнал. 2018;4(159):21-24. [M.A.M. Al-Qufaish, I.N. Usmanova, I.R. Usmanov, R.F. Khusnarizanova, N.D. Galiaskarov. Assessment of dental status of young people. Ural Medical Journal. 2018;4(159):21-24. (In Russ.)]. https://doi.org/10.25694/URMJ.2018.04.035</mixed-citation>
     <mixed-citation xml:lang="en">Al'-Kofish M.A.M., Usmanova I.N., Usmanov I.R., Husnarizanova R.F., Galiaskarov N.D. Ocenka sostoyaniya stomatologicheskogo statusa lic molodogo vozrasta. Ural'skiy medicinskiy zhurnal. 2018;4(159):21-24. [M.A.M. Al-Qufaish, I.N. Usmanova, I.R. Usmanov, R.F. Khusnarizanova, N.D. Galiaskarov. Assessment of dental status of young people. Ural Medical Journal. 2018;4(159):21-24. (In Russ.)]. https://doi.org/10.25694/URMJ.2018.04.035</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Айвазов Р.А., Аксамит Л.А., Акуленко Л.В. и др. Пародонтология. Национальное руководство. 2-е изд., перераб. и доп. Москва : ГЭОТАР-Медиа. 2018:752. [R.A. Aivazov, L.A. Aksamit, L.V. Akulenko et al. Periodontology. A national guide. 2nd edition. Moscow : GEOTAR-Media. 2018:752. (In Russ.)]. https://elibrary.ru/item.asp?id=32309767</mixed-citation>
     <mixed-citation xml:lang="en">Ayvazov R.A., Aksamit L.A., Akulenko L.V. i dr. Parodontologiya. Nacional'noe rukovodstvo. 2-e izd., pererab. i dop. Moskva : GEOTAR-Media. 2018:752. [R.A. Aivazov, L.A. Aksamit, L.V. Akulenko et al. Periodontology. A national guide. 2nd edition. Moscow : GEOTAR-Media. 2018:752. (In Russ.)]. https://elibrary.ru/item.asp?id=32309767</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B13">
    <label>13.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Цепов Л.М., Николаев А.И., Нестерова М.М., Цепова Е.Л. Патогенетические особенности формирования хронической воспалительной патологии пародонта (обзор). Вестник Смоленской государственной медицинской академии. 2018;3(17):206-214. [L.M. Tsepov, A.I. Nikolaev, M.M. Nesterova, E.L. Tsepova. Pathogenetic features of chronic periodontal pathology development (review). Vestnik of the smolensk state medical academy. 2018;3(17):198-205. (In Russ.)]. https://elibrary.ru/item.asp?id=35722173</mixed-citation>
     <mixed-citation xml:lang="en">Cepov L.M., Nikolaev A.I., Nesterova M.M., Cepova E.L. Patogeneticheskie osobennosti formirovaniya hronicheskoy vospalitel'noy patologii parodonta (obzor). Vestnik Smolenskoy gosudarstvennoy medicinskoy akademii. 2018;3(17):206-214. [L.M. Tsepov, A.I. Nikolaev, M.M. Nesterova, E.L. Tsepova. Pathogenetic features of chronic periodontal pathology development (review). Vestnik of the smolensk state medical academy. 2018;3(17):198-205. (In Russ.)]. https://elibrary.ru/item.asp?id=35722173</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B14">
    <label>14.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Саблина С.Н., Еловикова Т.М., Григорьев С.С. и др. Проблема галитоза в комплексной диагностике и лечении заболеваний пародонта. Литературный обзор. Проблемы стоматологии. 2021;17(1):32-43. [S.N. Sablina, T.M. Elovicova, S.S. Griroriev et al. The problem of halitosis in periodontal complex diagnostics and treatment. Literature review. Actual Problems In Dentistry. 2021;17(1):32-43. (In Russ.)]. Doi:10.18481/2077-7566-20-17-1-32-43</mixed-citation>
     <mixed-citation xml:lang="en">Sablina S.N., Elovikova T.M., Grigor'ev S.S. i dr. Problema galitoza v kompleksnoy diagnostike i lechenii zabolevaniy parodonta. Literaturnyy obzor. Problemy stomatologii. 2021;17(1):32-43. [S.N. Sablina, T.M. Elovicova, S.S. Griroriev et al. The problem of halitosis in periodontal complex diagnostics and treatment. Literature review. Actual Problems In Dentistry. 2021;17(1):32-43. (In Russ.)]. Doi:10.18481/2077-7566-20-17-1-32-43</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B15">
    <label>15.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Орехова Л.Ю., Кудрявцева Т.В., Атрушкевич В.Г. и др. Системные факторы и болезни пародонта. Учебное пособие. Санкт-Петербург. 2020:64. [L.Yu. Orekhova, T.V. Kudryavtseva, V.G. Atrushkevich et al. Systemic factors and periodontal disease. Tutorial. St. Petersburg. 2020:64. (In Russ.)]. https://elibrary.ru/item.asp?id=44498589</mixed-citation>
     <mixed-citation xml:lang="en">Orehova L.Yu., Kudryavceva T.V., Atrushkevich V.G. i dr. Sistemnye faktory i bolezni parodonta. Uchebnoe posobie. Sankt-Peterburg. 2020:64. [L.Yu. Orekhova, T.V. Kudryavtseva, V.G. Atrushkevich et al. Systemic factors and periodontal disease. Tutorial. St. Petersburg. 2020:64. (In Russ.)]. https://elibrary.ru/item.asp?id=44498589</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B16">
    <label>16.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Холмструп П., Племонс Ж., Мейл Й. Новая классификация заболеваний пародонта и тканей вокруг имплантатов. Заболевания десен, не ассоциированные с зубной бляшкой. Пародонтология. 2019;1(90):101-104. [P. Holmstrup, J. Plemons, J. Meyle. Non-plaque-induced gingival diseases. Parodontologiya. 2019;1(90):101-104. (In Russ.)]. https://elibrary.ru/item.asp?id=41531663</mixed-citation>
     <mixed-citation xml:lang="en">Holmstrup P., Plemons Zh., Meyl Y. Novaya klassifikaciya zabolevaniy parodonta i tkaney vokrug implantatov. Zabolevaniya desen, ne associirovannye s zubnoy blyashkoy. Parodontologiya. 2019;1(90):101-104. [P. Holmstrup, J. Plemons, J. Meyle. Non-plaque-induced gingival diseases. Parodontologiya. 2019;1(90):101-104. (In Russ.)]. https://elibrary.ru/item.asp?id=41531663</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B17">
    <label>17.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Осипова М.В., Орехова Л.Ю., Белова Е.А. Эпидемиологические показатели и модель развития, профилактики и лечения воспалительных заболеваний пародонта у курящего населения. Проблемы стоматологии. 2018;14(4):38-44. [M.V. Osipova, L.Yu. Orehova, E.A. Belova. Epidemiological indicators and the pattern of development, prevention and treatment of inflammatory periodontal diseases in the smoking population. Actual Problems In Dentistry. 2018;14(4):38-44. (In Russ.)]. https://doi.org/10.18481/2077-7566-2018-14-4-38-44</mixed-citation>
     <mixed-citation xml:lang="en">Osipova M.V., Orehova L.Yu., Belova E.A. Epidemiologicheskie pokazateli i model' razvitiya, profilaktiki i lecheniya vospalitel'nyh zabolevaniy parodonta u kuryaschego naseleniya. Problemy stomatologii. 2018;14(4):38-44. [M.V. Osipova, L.Yu. Orehova, E.A. Belova. Epidemiological indicators and the pattern of development, prevention and treatment of inflammatory periodontal diseases in the smoking population. Actual Problems In Dentistry. 2018;14(4):38-44. (In Russ.)]. https://doi.org/10.18481/2077-7566-2018-14-4-38-44</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B18">
    <label>18.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Абдрахманов А.К., Мамаева Е.В., Яковлева Г.Ю., Ильинская О.Н. Ювенильный пародонтит - видовая принадлежность выделенных микроорганизмов. Стоматология детского возраста и профилактика. 2016;15;3(58):4-9. [A.K. Abdrakhmanov, E.V. Mamaeva, G.YU. Yakovleva, O.N. Ilyinskaya. Juvenile periodontitis is the species of isolated microorganisms. Pediatric dentistry and prevention. 2016;15;3(58):4-9. (In Russ.)]. https://elibrary.ru/item.asp?id=27196908</mixed-citation>
     <mixed-citation xml:lang="en">Abdrahmanov A.K., Mamaeva E.V., Yakovleva G.Yu., Il'inskaya O.N. Yuvenil'nyy parodontit - vidovaya prinadlezhnost' vydelennyh mikroorganizmov. Stomatologiya detskogo vozrasta i profilaktika. 2016;15;3(58):4-9. [A.K. Abdrakhmanov, E.V. Mamaeva, G.YU. Yakovleva, O.N. Ilyinskaya. Juvenile periodontitis is the species of isolated microorganisms. Pediatric dentistry and prevention. 2016;15;3(58):4-9. (In Russ.)]. https://elibrary.ru/item.asp?id=27196908</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B19">
    <label>19.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Янушевич О.О., Дмитриева Л.А., Грудянов А.И. Пародонтит XXI век. Москва. 2012:186. [O.O. Janushevich, L.A. Dmitrieva, A.I. Grudjanov. Periodontitis XXI century. Moscow. 2012:186. (In Russ.)]. https://elibrary.ru/item.asp?id=26551454</mixed-citation>
     <mixed-citation xml:lang="en">Yanushevich O.O., Dmitrieva L.A., Grudyanov A.I. Parodontit XXI vek. Moskva. 2012:186. [O.O. Janushevich, L.A. Dmitrieva, A.I. Grudjanov. Periodontitis XXI century. Moscow. 2012:186. (In Russ.)]. https://elibrary.ru/item.asp?id=26551454</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B20">
    <label>20.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Ambili R., Preeja C., Archana V. et al. Viruses: are they really culprits for periodontal disease? A critical review // J. Investig. Clin. Dent. - 2013;5(3):179-187. https://doi.org/10.1111/jicd.12029</mixed-citation>
     <mixed-citation xml:lang="en">Ambili R., Preeja C., Archana V. et al. Viruses: are they really culprits for periodontal disease? A critical review // J. Investig. Clin. Dent. - 2013;5(3):179-187. https://doi.org/10.1111/jicd.12029</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B21">
    <label>21.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fujinaka H., Takeshita T., Sato H. et al. Relationship of periodontal clinical parameters with bacterial composition in human dental plaque // Arch. Microbiol. - 2013;6(195):371-383. https://doi.org/10.1007/s00203-013-0883-9</mixed-citation>
     <mixed-citation xml:lang="en">Fujinaka H., Takeshita T., Sato H. et al. Relationship of periodontal clinical parameters with bacterial composition in human dental plaque // Arch. Microbiol. - 2013;6(195):371-383. https://doi.org/10.1007/s00203-013-0883-9</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B22">
    <label>22.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Jessica L. Mark Welch, Blair J. Rossetti, Christopher W. Rieken, Floyd E. Dewhirst, Gary G. Borisy. Biogeography of a human oral microbiome at the micron scale // Proc Natl Acad Sci USA. - 2016;9;113(6):E791-E800. https://doi.org/10.1073/pnas.1522149113</mixed-citation>
     <mixed-citation xml:lang="en">Jessica L. Mark Welch, Blair J. Rossetti, Christopher W. Rieken, Floyd E. Dewhirst, Gary G. Borisy. Biogeography of a human oral microbiome at the micron scale // Proc Natl Acad Sci USA. - 2016;9;113(6):E791-E800. https://doi.org/10.1073/pnas.1522149113</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B23">
    <label>23.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Könönen E., Gursoy M., Gursoy U.K. Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues // J Clin Med. - 2019;8(8):1135. https://doi.org/10.3390/jcm8081135.</mixed-citation>
     <mixed-citation xml:lang="en">Könönen E., Gursoy M., Gursoy U.K. Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues // J Clin Med. - 2019;8(8):1135. https://doi.org/10.3390/jcm8081135.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B24">
    <label>24.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Koo H., Andes D.R., Krysan D.J. Candida-streptococcal interactions in biofilm-associated oral diseases // PLoS Pathog. - 2018;14:e1007342. https://doi.org/10.1371/journal.ppat.1007342</mixed-citation>
     <mixed-citation xml:lang="en">Koo H., Andes D.R., Krysan D.J. Candida-streptococcal interactions in biofilm-associated oral diseases // PLoS Pathog. - 2018;14:e1007342. https://doi.org/10.1371/journal.ppat.1007342</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B25">
    <label>25.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Tachalov V.V, Orechova L.Y, Kudriavtseva T.V, Loboda E.S et. al. Making a complex dental care tailored to the person: Population health in focus of predictive, preventive and personalised (3P) medical approach // EPMA Journal. - 2021;12(2):129-140. https://doi.org/10.21203/rs.3.rs-362468/v1</mixed-citation>
     <mixed-citation xml:lang="en">Tachalov V.V, Orechova L.Y, Kudriavtseva T.V, Loboda E.S et. al. Making a complex dental care tailored to the person: Population health in focus of predictive, preventive and personalised (3P) medical approach // EPMA Journal. - 2021;12(2):129-140. https://doi.org/10.21203/rs.3.rs-362468/v1</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B26">
    <label>26.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Tachalov V.V, Orechova L.Y., Kudriavtseva T.V, Isaeva E.R., Loboda E.S. Manifestations of personal characteristics in individual oral care // EPMA Journal. - 2016;7:8. https://doi.org/10.1186/s13167-016-0058-2</mixed-citation>
     <mixed-citation xml:lang="en">Tachalov V.V, Orechova L.Y., Kudriavtseva T.V, Isaeva E.R., Loboda E.S. Manifestations of personal characteristics in individual oral care // EPMA Journal. - 2016;7:8. https://doi.org/10.1186/s13167-016-0058-2</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B27">
    <label>27.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kharitonova M., Vankov P., Yakovleva G., Ilinskaya O., Abdrakhmanov A., Mamaeva E. The composition of microbial communities in inflammatory periodontal diseases in young adults tatars // AIMS Microbiology. - 2021;7;1:59-74. https://doi.org/10.3934/microbiol.2021005</mixed-citation>
     <mixed-citation xml:lang="en">Kharitonova M., Vankov P., Yakovleva G., Ilinskaya O., Abdrakhmanov A., Mamaeva E. The composition of microbial communities in inflammatory periodontal diseases in young adults tatars // AIMS Microbiology. - 2021;7;1:59-74. https://doi.org/10.3934/microbiol.2021005</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
