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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">40251</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-20-16-4-97-103</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ХИРУРГИЧЕСКАЯ СТОМАТОЛОГИЯ И  ИМПЛАНТОЛОГИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>SURGICAL DENTISTRY AND IMPLANTOLOGY</subject>
    </subj-group>
    <subj-group>
     <subject>ХИРУРГИЧЕСКАЯ СТОМАТОЛОГИЯ И  ИМПЛАНТОЛОГИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">CLINICAL STUDIES OF THE STABILITY AND PROCESS OF OSTEOINTEGRATION OF DENTAL IMPLANTS DURING IMMEDIATE AND DELAYED IMPLANTATION</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ СТАБИЛЬНОСТИ И ПРОЦЕССА ОСТЕОИНТЕГРАЦИИ ДЕНТАЛЬНЫХ ИМПЛАНТАТОВ ПРИ ПРОВЕДЕНИИ НЕПОСРЕДСТВЕННОЙ И ОТСРОЧЕННОЙ ИМПЛАНТАЦИИ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гришин</surname>
       <given-names>Петр Олегович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Grishin</surname>
       <given-names>Petr Olegovit</given-names>
      </name>
     </name-alternatives>
     <email>phlus8@mail.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Калинникова</surname>
       <given-names>Елена Александровна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Kalinnikova</surname>
       <given-names>Elena Aleksandrovna</given-names>
      </name>
     </name-alternatives>
     <email>elena-vilkova@inbox.ru</email>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Казанский государственный медицинский университет</institution>
    </aff>
    <aff>
     <institution xml:lang="en">Kazan State Medical University</institution>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Казанский государственный медицинский университет</institution>
     <city>Казань</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Kazan State Medical University</institution>
     <city>Kazan</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2020-12-28T12:06:08+03:00">
    <day>28</day>
    <month>12</month>
    <year>2020</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2020-12-28T12:06:08+03:00">
    <day>28</day>
    <month>12</month>
    <year>2020</year>
   </pub-date>
   <volume>16</volume>
   <issue>4</issue>
   <fpage>97</fpage>
   <lpage>103</lpage>
   <history>
    <date date-type="received" iso-8601-date="2020-12-03T12:06:08+03:00">
     <day>03</day>
     <month>12</month>
     <year>2020</year>
    </date>
    <date date-type="accepted" iso-8601-date="2020-12-10T12:06:08+03:00">
     <day>10</day>
     <month>12</month>
     <year>2020</year>
    </date>
   </history>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/article/40251/view">https://dental-press.ru/en/nauka/article/40251/view</self-uri>
   <abstract xml:lang="ru">
    <p>Предмет. Анализ литературных данных подтверждает, что существует определенная связь между микроструктурой поверхности, геометрией имплантата, дизайном резьбы и первичной стабильностью, а также процессами остеоинтеграции. К настоящему времени накопилось достаточное количество работ по непосредственной и отсроченной имплантации. Однако убедительных клинических данных количественной оценки первичной стабильности в различные сроки остеоинтеграционного процесса недостаточно. Несмотря на наличие экспериментальных и клинических наблюдений, составить определенное суждение о механизме такой связи не представляется возможным. В настоящей главе представлены клинические исследования стабильности и остеоинтеграции дентальных имплантатов при проведении по показаниям у 414 пациентов непосредственной и отсроченной имплантации с использованием имплантационных систем с различной микроструктурой поверхности.&#13;
Цель – провести клинические исследования количественных показателей стабильности и остеоинтеграции имплантатов c различной микроструктурой поверхности при проведении непосредственной и отсроченной имплантации.&#13;
Методология. Для клинического исследования первичной стабильности и процесса остеоинтеграции при проведении непосредственной и отсроченной имплантации с немедленной функциональной нагрузкой использовались имплантационные системы с различной микроструктурой поверхности: Alfa Bio, Mis, Astra-Tech, Dentium, Ostem, Antogher, а также Humana Dental c инновационной поверхностью. Остеоинтегрированные имплантаты были использованы для достижения предсказуемого результата лечения в клинических случаях с частичной или полной адентией, а также при наличии одиночных, включенных дефектов.&#13;
Результаты. Существенных различий показателей стабильности в момент установки имплантатов в альвеолярную кость в зависимости от типа имплантата и метода проведения имплантации не выявлено.&#13;
Выводы. В процессе интеграции имплантата в костной ткани на более поздних сроках показатели стабильности и остеоинтеграции улучшаются. Выявлена связь между видом поверхности имплантата, первичной стабильностью и временем его адаптации.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Subject. Analysis of the literature confirms that there is a definite relationship between surface microstructure, implant geometry, thread design and primary stability, and osseointegration processes. To date, a sufficient number of works on direct and delayed implantation have accumulated. However, there is not enough convincing clinical data on the quantitative assessment of primary stability at different periods of the osseointegration process. Despite the existence of experimental and clinical observations, it seems impossible to make a definite judgment about the mechanism of such a relationship. This chapter presents clinical studies of the stability and osseointegration of dental implants when performing, according to the indications, in 414 patients of direct and delayed implantation using implant systems with different surface microstructures.&#13;
Goal.  Conduct clinical studies of quantitative indicators of stability and osseointegration of implants with different microstructure of the surface during direct and delayed implantation.&#13;
Methodology. For the clinical study of primary stability and the process of osseointegration during direct and delayed implantation with immediate functional loading, implant systems with different surface microstructures were used: Alfa Bio, Mis, Astra-Tech, Dentium, Ostem, Antogher, and also Humana Dental with an innovative surface. Osseointegrated implants have been used to achieve a predictable treatment outcome in clinical cases with partial or complete adentia, as well as in the presence of single, included defects.&#13;
Results. There were no significant differences in stability indicators at the time of implant placement in the alveolar bone, depending on the type of implant and the method of implantation.&#13;
Conclusions. In the process of integration of the implant into the bone tissue at a later date, the indicators of stability and osseointegration improve. The relationship between the appearance of the implant surface, primary stability and the time of its adaptation was revealed.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>частотно-резонансный анализ</kwd>
    <kwd>демпфирование</kwd>
    <kwd>стабильность</kwd>
    <kwd>остеоинтеграция</kwd>
    <kwd>фиксация</kwd>
    <kwd>имплантаты</kwd>
    <kwd>периотестометрия</kwd>
    <kwd>непосредственная имплантация</kwd>
    <kwd>стоматология</kwd>
    <kwd>клинические исследования</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>frequency resonance analysis</kwd>
    <kwd>damping</kwd>
    <kwd>stability</kwd>
    <kwd>osseointegration</kwd>
    <kwd>fixation</kwd>
    <kwd>implants</kwd>
    <kwd>periotestometry</kwd>
    <kwd>immediate implantation</kwd>
    <kwd>dentistry</kwd>
    <kwd>clinical study</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Elise G., Zuiderveld A., Meijer J. Henny, Vissink Ajian, Raghoebar M. Gerry. Immediate placement and privisionalization of an implants after removal of n impacted maxillary canine:  two case reports // International Journal of Implants Dentistry. - 2015; 1: 13-19.</mixed-citation>
     <mixed-citation xml:lang="en">Elise G., Zuiderveld A., Meijer J. Henny, Vissink Ajian, Raghoebar M. Gerry. Immediate placement and privisionalization of an implants after removal of n impacted maxillary canine:  two case reports // International Journal of Implants Dentistry. - 2015; 1: 13-19.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Naves M. M., Maezes H. H., Magalhaes D. Effect of microgeometry on the surface topography of dental implants // International Journal of implants Dentistry. - 2015; 30 (4): 789-799.</mixed-citation>
     <mixed-citation xml:lang="en">Naves M. M., Maezes H. H., Magalhaes D. Effect of microgeometry on the surface topography of dental implants // International Journal of implants Dentistry. - 2015; 30 (4): 789-799.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Cervino G., Romeo U., Lauritano F. Fem and von mises analysis of Osstem dental implant structural components: evaluation off different direction dynamic loads // The Open Dentistry Journal. - 2018; 12 (1): 99-239.</mixed-citation>
     <mixed-citation xml:lang="en">Cervino G., Romeo U., Lauritano F. Fem and von mises analysis of Osstem dental implant structural components: evaluation off different direction dynamic loads // The Open Dentistry Journal. - 2018; 12 (1): 99-239.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Sencimen M., Gulses A., Ozen J. et al. Early detection of alterations in the resonance frequency assessment of oral implant stability on various bone types: A clinical study // J Oral Implantol. - 2011; 37: 411-419.</mixed-citation>
     <mixed-citation xml:lang="en">Sencimen M., Gulses A., Ozen J. et al. Early detection of alterations in the resonance frequency assessment of oral implant stability on various bone types: A clinical study // J Oral Implantol. - 2011; 37: 411-419.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Hulton J. E., Heath M. R., Chai J. Y. et al. Factors related to success and failure rate dental implants. A systematic review // Clin Oral Implants Res. - 2012; 23: 767-774.</mixed-citation>
     <mixed-citation xml:lang="en">Hulton J. E., Heath M. R., Chai J. Y. et al. Factors related to success and failure rate dental implants. A systematic review // Clin Oral Implants Res. - 2012; 23: 767-774.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Jeong M. A., Kim S. G., Kim Y. K. et al., A multicenter prospective study in type IV bone of a single type of implant // Implant Dent. - 2012; 21: 330-334.</mixed-citation>
     <mixed-citation xml:lang="en">Jeong M. A., Kim S. G., Kim Y. K. et al., A multicenter prospective study in type IV bone of a single type of implant // Implant Dent. - 2012; 21: 330-334.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Simune A., Strnad J., Kopecka D. et al. Changes in stability after healing of immediately loaded dental implants // Int J Oral Maxillofac Implants. - 2010; 25: 1085- 1092.</mixed-citation>
     <mixed-citation xml:lang="en">Simune A., Strnad J., Kopecka D. et al. Changes in stability after healing of immediately loaded dental implants // Int J Oral Maxillofac Implants. - 2010; 25: 1085- 1092.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Mohanad Al-Sabbagh, Walied Eldomiaty. Yasser Khabbaz. Can osseointegration be without primary stability? // Dent Clin Noeth Arm. - 2019; 63 (3): 461- 463.</mixed-citation>
     <mixed-citation xml:lang="en">Mohanad Al-Sabbagh, Walied Eldomiaty. Yasser Khabbaz. Can osseointegration be without primary stability? // Dent Clin Noeth Arm. - 2019; 63 (3): 461- 463.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Trisi P., Berardini M., Falco A. et al. Effect of implant thread geometry on secondary stability, bone density, and bone-to-implant contact: a biomechanical and histological analysis // Implant Dent. - 2015; 24: 384-391.</mixed-citation>
     <mixed-citation xml:lang="en">Trisi P., Berardini M., Falco A. et al. Effect of implant thread geometry on secondary stability, bone density, and bone-to-implant contact: a biomechanical and histological analysis // Implant Dent. - 2015; 24: 384-391.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Strub J. R., Judzik B. A., Tuna T. Prognosis of immediately loaded implants and their restorations: a systematic literature review // J Oral Rehabil. - 2012; 39: 704-717.</mixed-citation>
     <mixed-citation xml:lang="en">Strub J. R., Judzik B. A., Tuna T. Prognosis of immediately loaded implants and their restorations: a systematic literature review // J Oral Rehabil. - 2012; 39: 704-717.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Atieh M. A., Alsabeeha M. H. M., Payne A. G. T. Can resonance frequency analysis predict failure risk of immediately loaded implants? // Int J Prostodont. - 2012; 25: 326-339.</mixed-citation>
     <mixed-citation xml:lang="en">Atieh M. A., Alsabeeha M. H. M., Payne A. G. T. Can resonance frequency analysis predict failure risk of immediately loaded implants? // Int J Prostodont. - 2012; 25: 326-339.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Bogaerde L. V., Pedretti G., Sennerby L. et al. Immediate /early function of Neoss implantsplacedin maxillas and posterior mandibles: an 18- month prospective case series study // Clin Implant Dent Relat Res. - 2010; 12: 83-94.</mixed-citation>
     <mixed-citation xml:lang="en">Bogaerde L. V., Pedretti G., Sennerby L. et al. Immediate /early function of Neoss implantsplacedin maxillas and posterior mandibles: an 18- month prospective case series study // Clin Implant Dent Relat Res. - 2010; 12: 83-94.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B13">
    <label>13.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Makovic A., Calvo-Guirado J. L., Lazic Z. et al. Evaluation of primary stability of self-tapping and non-self-tapping dental implants. A 12 - week clinical study // Clin Implant Dent Relat Res. - 2013; 15: 341-349.</mixed-citation>
     <mixed-citation xml:lang="en">Makovic A., Calvo-Guirado J. L., Lazic Z. et al. Evaluation of primary stability of self-tapping and non-self-tapping dental implants. A 12 - week clinical study // Clin Implant Dent Relat Res. - 2013; 15: 341-349.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B14">
    <label>14.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Xing Yin, Jingtao Li, Waldemar Hoffman, Angelines Gasser et al. Mechanical and biological advantages of tri -oval implant design // J Clin Med. - 2019; 28, 8 (4): 427-436.</mixed-citation>
     <mixed-citation xml:lang="en">Xing Yin, Jingtao Li, Waldemar Hoffman, Angelines Gasser et al. Mechanical and biological advantages of tri -oval implant design // J Clin Med. - 2019; 28, 8 (4): 427-436.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B15">
    <label>15.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fabbro M. D., Tascieri S., Canciani F., Addis S. Osseointegration of titanium Implants with different rough surface: histologic and histomorphometric study in adult miniping model // Implant Dent. - 2017; 28: 357-366.</mixed-citation>
     <mixed-citation xml:lang="en">Fabbro M. D., Tascieri S., Canciani F., Addis S. Osseointegration of titanium Implants with different rough surface: histologic and histomorphometric study in adult miniping model // Implant Dent. - 2017; 28: 357-366.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B16">
    <label>16.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Macary C., Menhall A., Zammarie C., Lombardi T. et al. Primary stability optimization by using fixtures with different thread depth loading implants // Materials (Basel). - 2019; 27, 12 (15): 398-411.</mixed-citation>
     <mixed-citation xml:lang="en">Macary C., Menhall A., Zammarie C., Lombardi T. et al. Primary stability optimization by using fixtures with different thread depth loading implants // Materials (Basel). - 2019; 27, 12 (15): 398-411.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B17">
    <label>17.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Jinno Y., Jimbo R., Tovar N., Taixeira H. S. et al. In vivo evaluation of dual acid- etched implants with identical microgeometry in high -density bone // Implants Dent. - 2017; 26: 815-819.</mixed-citation>
     <mixed-citation xml:lang="en">Jinno Y., Jimbo R., Tovar N., Taixeira H. S. et al. In vivo evaluation of dual acid- etched implants with identical microgeometry in high -density bone // Implants Dent. - 2017; 26: 815-819.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B18">
    <label>18.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Ritte I. D., Dorogoy A., Shemtov-Yona K. Modeling the effect of osseointegration on dental implants pullout and torque removal tests // Clinical Implant Dentistry and Relate Research. - 2018; 86 (2051): 713-720.</mixed-citation>
     <mixed-citation xml:lang="en">Ritte I. D., Dorogoy A., Shemtov-Yona K. Modeling the effect of osseointegration on dental implants pullout and torque removal tests // Clinical Implant Dentistry and Relate Research. - 2018; 86 (2051): 713-720.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B19">
    <label>19.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Gaetano Marenzi, Glanrico Spagnuolo, Sammartino Jone Amilla et al. Micro- scae surface patterning of titanium dental implants by anodization in the presence of modifying salts // Materials (Basel). - 2019; 12 (11): 1753- 1764.</mixed-citation>
     <mixed-citation xml:lang="en">Gaetano Marenzi, Glanrico Spagnuolo, Sammartino Jone Amilla et al. Micro- scae surface patterning of titanium dental implants by anodization in the presence of modifying salts // Materials (Basel). - 2019; 12 (11): 1753- 1764.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B20">
    <label>20.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Mello C. C., Lemos S. A., Verri F. R., Dos Santos D. M. et al. Immediate implant placement into fresh extraction sockets versus delayed implants into healed sockets: a systematic review and meta - analysis // Int J Oral Maxillofac Surg. - 2017; 26 (9): 1162- 1177.</mixed-citation>
     <mixed-citation xml:lang="en">Mello C. C., Lemos S. A., Verri F. R., Dos Santos D. M. et al. Immediate implant placement into fresh extraction sockets versus delayed implants into healed sockets: a systematic review and meta - analysis // Int J Oral Maxillofac Surg. - 2017; 26 (9): 1162- 1177.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B21">
    <label>21.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Pigozo M. N., Rebelo da Costa T., Sesma N., Lagana D. C. Immediate versus early loading of single dental implants: a systematic review and analisis // J Prosthet Dent. - 2018; 120 (1): 25-34.</mixed-citation>
     <mixed-citation xml:lang="en">Pigozo M. N., Rebelo da Costa T., Sesma N., Lagana D. C. Immediate versus early loading of single dental implants: a systematic review and analisis // J Prosthet Dent. - 2018; 120 (1): 25-34.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B22">
    <label>22.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Бунев Ф. А., Мураев А. А., Гажва Ю. В., Мухаметшин Р. В. и др. Результаты непосредственной дентальной имплантации с немедленной нагрузкой и обоснование протокола математического моделирования. Журнал научных статей. Здоровье и образование в ХХI веке. 2018; 20, 9: 62-69. [F. A. Bunev, A. A. Muraev, Yu. V. Gazhva, R. V. Mukhametshin et al. Results of direct dental implantation with immediate loading and substantiation of the mathematical modeling protocol. Journal of scientific articles. Health and education in the XXI century. 2018; 20, 9: 62-69. (In Russ.)].</mixed-citation>
     <mixed-citation xml:lang="en">Bunev F. A., Muraev A. A., Gazhva Yu. V., Muhametshin R. V. i dr. Rezul'taty neposredstvennoy dental'noy implantacii s nemedlennoy nagruzkoy i obosnovanie protokola matematicheskogo modelirovaniya. Zhurnal nauchnyh statey. Zdorov'e i obrazovanie v HHI veke. 2018; 20, 9: 62-69. [F. A. Bunev, A. A. Muraev, Yu. V. Gazhva, R. V. Mukhametshin et al. Results of direct dental implantation with immediate loading and substantiation of the mathematical modeling protocol. Journal of scientific articles. Health and education in the XXI century. 2018; 20, 9: 62-69. (In Russ.)].</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B23">
    <label>23.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Панахов Н. А. О., Махмудов Т.Г.О. Уровень стабильности зубных имплантатов в различные сроки функционирования. Проблемы стоматологии. 2018; 14, 1: 89-93. [N. A. O. Panahov, T. G. O. Makhmudov. The level of stability of dental implants at different periods of operation. Actual problems in dentistry. 2018; 14, 1: 89-93. (In Russ.)]. https://www.elibrary.ru/item.asp?id=32840697</mixed-citation>
     <mixed-citation xml:lang="en">Panahov N. A. O., Mahmudov T.G.O. Uroven' stabil'nosti zubnyh implantatov v razlichnye sroki funkcionirovaniya. Problemy stomatologii. 2018; 14, 1: 89-93. [N. A. O. Panahov, T. G. O. Makhmudov. The level of stability of dental implants at different periods of operation. Actual problems in dentistry. 2018; 14, 1: 89-93. (In Russ.)]. https://www.elibrary.ru/item.asp?id=32840697</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B24">
    <label>24.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Сысолятин П. Г., Гюнтер В. Э., Железный П. А., Железный С. П. Остеоинтеграция различных имплантатов при пересадке костного аутотранпплантата в дефект нижнем челюсти в эксперименте. Проблемы стоматологии. 2006; 5-6: 34-36. [P. G. Sysolyatin, V. E. Gunther, P. A. Zhelezny, S. P. Zhelezny. Osseointegration of various implants during transplantation of a bone autograft into a defect in the lower jaw in the experiment. Actual problems in dentistry. 2006; 5-6: 34-36. (In Russ.)].</mixed-citation>
     <mixed-citation xml:lang="en">Sysolyatin P. G., Gyunter V. E., Zheleznyy P. A., Zheleznyy S. P. Osteointegraciya razlichnyh implantatov pri peresadke kostnogo autotranpplantata v defekt nizhnem chelyusti v eksperimente. Problemy stomatologii. 2006; 5-6: 34-36. [P. G. Sysolyatin, V. E. Gunther, P. A. Zhelezny, S. P. Zhelezny. Osseointegration of various implants during transplantation of a bone autograft into a defect in the lower jaw in the experiment. Actual problems in dentistry. 2006; 5-6: 34-36. (In Russ.)].</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B25">
    <label>25.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Асташина Н. Б., Плюхин Д. В., Делец А. В. Прогнозирование исходов дентальной имплантации на основе изучения уровня продуктов окислительной модификации белков слюны. Проблемы стоматологии. 2017; 13, 3: 47-52. [N. B. Astashina, D. V. Plyukhin, A. V. Delets. Predicting the outcomes of dental implantation based on studying the level of products of oxidative modification of saliva proteins. Actual problems in dentistry. 2017; 13, 3: 47-52. (In Russ.)].</mixed-citation>
     <mixed-citation xml:lang="en">Astashina N. B., Plyuhin D. V., Delec A. V. Prognozirovanie ishodov dental'noy implantacii na osnove izucheniya urovnya produktov okislitel'noy modifikacii belkov slyuny. Problemy stomatologii. 2017; 13, 3: 47-52. [N. B. Astashina, D. V. Plyukhin, A. V. Delets. Predicting the outcomes of dental implantation based on studying the level of products of oxidative modification of saliva proteins. Actual problems in dentistry. 2017; 13, 3: 47-52. (In Russ.)].</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
