Objectives. The outcome of a successful operation on plastic surgery of a congenital cleft palate depends not only on the technically correct performance of uranoplasty by surgeons, but also on preoperative and postoperative management. Before the operation of uranoplasty, oral cavity sanitation is certainly important and there are effective methods of preoperative preparation of patients, but there are few effective methods of local therapy in the postoperative period, therefore we decided to use a complex of complications prevention, including local herbal medicine and magnetolaser therapy. Purpose. To evaluate the effectiveness of complex prevention of complications after uranoplasty in children with congenital cleft palate, including local herbal medicine and magnetic laser therapy in the early postoperative period. Methodology. The study involved 150 children with congenital cleft palate, who were divided into 4 groups depending on the complex of complications prevention after uranoplasty. In group 1 there were 45 children, whose postoperative observation was standard. In group 2 there were 45 children who were given local phytotherapy with a patented phytocomplex. In group 3 there were 30 children who underwent magnetolaser therapy in the postoperative period. In group 4 there were 30 children, in the complex of complications prevention after uranoplasty for whom local phytotherapy and magnetolaser therapy were included. The following were assessed on the 10th day after the operation: the condition of the postoperative wound, complications after uranoplasty, determination of physicochemical, biochemical and immunological parameters of oral fluid, cytology of smears-imprints, features of capillary blood flow using the laser Doppler flowmetry method, nasopharyngoscopy. Results. In the group of children who were treated with the patented local phytotherapy with a prolonged-action phytocomplex and magnetolaser therapy in the early postoperative period, the condition of the postoperative wound was clinically and cytologically without wound inflammation, the most significant improvement was in the indices of oral fluid and capillary blood flow, according to nasopharyngoscopy data, complete closure occurred 10 days after uranoplasty.