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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">6a9c168332807fdbab876519</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-2026-22-3-26-33</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ТЕРАПЕВТИЧЕСКАЯ СТОМАТОЛОГИЯ. ОБЗОРЫ ЛИТЕРАТУРЫ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>TERAPEUTIC DENTISTRY. REVIEWS</subject>
    </subj-group>
    <subj-group>
     <subject>ТЕРАПЕВТИЧЕСКАЯ СТОМАТОЛОГИЯ. ОБЗОРЫ ЛИТЕРАТУРЫ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">THE RELATIONSHIP BETWEEN AGING, COGNITIVE DISORDERS, AND ORAL HEALTH IN PATIENTS</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ВЗАИМОСВЯЗЬ МЕЖДУ СТАРЕНИЕМ, КОГНИТИВНЫМИ НАРУШЕНИЯМИ И СОСТОЯНИЕМ ЗДОРОВЬЯ ПОЛОСТИ РТА ПАЦИЕНТОВ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Исанина</surname>
       <given-names>Светлана Олеговна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Isanina</surname>
       <given-names>Svetlana O.</given-names>
      </name>
     </name-alternatives>
     <email>isanina@unn.ru</email>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Комарова</surname>
       <given-names>Мария Александровна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Komarova</surname>
       <given-names>Maria A.</given-names>
      </name>
     </name-alternatives>
     <email>masha.komarova.2016@list.ru</email>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Тиунова</surname>
       <given-names>Наталья Викторовна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Tiunova</surname>
       <given-names>Natalia V.</given-names>
      </name>
     </name-alternatives>
     <email>natali5_@list.ru</email>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Исанин</surname>
       <given-names>Алексей Алексеевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Isanin</surname>
       <given-names>Alexey A.</given-names>
      </name>
     </name-alternatives>
     <email>isanin.nmk@yandex.ru</email>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Голдобина</surname>
       <given-names>Полина Владимировна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Goldobina</surname>
       <given-names>Polina V.</given-names>
      </name>
     </name-alternatives>
     <email>pelagold_nn.52@mail.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Плишкина</surname>
       <given-names>Анна Александровна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Plishkina</surname>
       <given-names>Anna Aleksandrovna</given-names>
      </name>
     </name-alternatives>
     <email>annaleksp@yandex.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Нижегородский государственный университет им. Н.И. Лобачевского</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Lobachevsky State University of Nizhny Novgorod</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Lobachevsky State University of Nizhny Novgorod</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Нижегородский государственный университет им. Н.И. Лобачевского</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Lobachevsky State University of Nizhny Novgorod</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Lobachevsky State University of Nizhny Novgorod</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Lobachevsky State University of Nizhny Novgorod</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Приволжский исследовательский медицинский университет</institution>
     <city xml:lang="ru">Нижний Новгород</city>
     <country country="RU" xml:lang="ru">Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Privolzhsky Research Medical University</institution>
     <city xml:lang="en">Nizhny Novgorod</city>
     <country country="RU" xml:lang="en">Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2026-09-23T20:06:12+00:00">
    <day>23</day>
    <month>09</month>
    <year>2026</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-09-23T20:06:12+00:00">
    <day>23</day>
    <month>09</month>
    <year>2026</year>
   </pub-date>
   <volume>22</volume>
   <issue>3</issue>
   <fpage>26</fpage>
   <lpage>33</lpage>
   <history>
    <date date-type="received" iso-8601-date="2026-08-24T21:00:00+00:00">
     <day>24</day>
     <month>08</month>
     <year>2026</year>
    </date>
   </history>
   <permissions>
    <copyright-statement xml:lang="ru">© 2026 Исанина С.О., Комарова М.А., Тиунова Н.В., Исанин А.А., Голдобина П.В., Плишкина А.А. Все права защищены.</copyright-statement>
    <copyright-statement xml:lang="en">© 2026 Isanina S.O., Komarova M.A., Tiunova N.V., Isanin A.A., Goldobina P.V., Plishkina A.A. All rights reserved.</copyright-statement>
    <copyright-year>2026</copyright-year>
    <copyright-holder xml:lang="ru">Исанина Светлана Олеговна, Комарова Мария Александровна, Тиунова Наталья Викторовна, Исанин Алексей Алексеевич, Голдобина Полина Владимировна, Плишкина Анна Александровна</copyright-holder>
    <copyright-holder xml:lang="en">Isanina Svetlana O., Komarova Maria A., Tiunova Natalia V., Isanin Alexey A., Goldobina Polina V., Plishkina Anna Aleksandrovna</copyright-holder>
   </permissions>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/publications/6a9c168332807fdbab876519/view">https://dental-press.ru/en/nauka/publications/6a9c168332807fdbab876519/view</self-uri>
   <abstract xml:lang="ru">
    <p>Актуальность. Старение – это многофакторный процесс инволюции всех систем организма, в развитии которого важную роль играют когнитивные нарушения. В настоящее время в научной литературе появляется все больше гипотез о том, что когнитивные изменения могут быть тесно связаны с патологиями полости рта, в том числе возраст-ассоциированными. Однако, такое взаимодействие не является односторонним. Состояние стоматологического здоровья также оказывает существенное влияние на развитие когнитивных дисфункций, а с ними – на процесс течения старения. Понимание когнитивно-стоматологического взаимодействия может стать важным шагом к управлению процессами старения.&#13;
	Предмет. Предмет исследования – современные данные о взаимосвязи когнитивных нарушений и состояния здоровья полости рта.&#13;
	Цель. Изучение, комплексный анализ научной литературы за 2015–2026 гг. и обобщение полученных данных для оценки двустороннего влияния между когнитивными нарушениями и состоянием полости рта.&#13;
	Материалы и методы. Проведен обзор научной литературы с 2015 по 2026 гг., посвященной когнитивно-стоматологическому синдрому, на основе анализа баз данных eLIBRARY, PubMed/MEDLINE, Google Scholar, Scopus.&#13;
	Результаты. Существует сильная, двусторонняя взаимосвязь между состоянием здоровья полости рта и когнитивными нарушениями, особенно у пациентов, имеющих признаки старения. &#13;
	Выводы &#13;
1. Со стороны полости рта наибольшее влияние на развитие когнитивных нарушений оказывают адентия (через снижение сенсорной интеграции, нутритивного дисбаланса, психологических трудностей) и воспаление пародонта, потенцирующее нейровоспаление.&#13;
2. Нейродегенеративные процессы, в свою очередь, приводят к невозможности проведения качественной и своевременной гигиены полости рта, трудностям в пережевывании твердой пищи, развитию орофациальной боли.&#13;
3. Понимание когнитивно-стоматологического взаимодействия может стать важным шагом к управлению процессами старения.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Relevance.  Aging is a multifactorial process of involution of all body systems, in which cognitive impairment plays a significant role. Currently, the scientific literature is increasingly replete with hypotheses suggesting that cognitive changes may be closely linked to oral pathologies, including age-related ones. However, this interaction is not one-sided. Dental health also significantly influences the development of cognitive dysfunctions, and thus the aging process. Understanding the cognitive-dental interaction may be an important step toward managing the aging process.&#13;
Subject. The subject of the study is current data on the relationship between cognitive impairment and oral health.&#13;
Objective. To study, comprehensively analyze, and summarize the data obtained from 2015–2026 to assess the two-way interaction between cognitive impairment and oral health.&#13;
Materials and methods. A review of the scientific literature on cognitive-dental syndrome from 2015 to 2026 was conducted using eLIBRARY, PubMed/MEDLINE, Google Scholar, and Scopus databases.&#13;
Results. There is a strong, bidirectional relationship between oral health and cognitive impairment, particularly in patients with signs of aging.&#13;
Conclusions.&#13;
1. From an oral perspective, the greatest impact on the development of cognitive impairment is adentia (through decreased sensory integration, nutritional imbalance, and psychological difficulties) and periodontal inflammation, which potentiates neuroinflammation.&#13;
2. Neurodegenerative processes, in turn, lead to the inability to maintain high-quality and timely oral hygiene, difficulty chewing hard foods, and the development of orofacial pain.&#13;
3. Understanding the cognitive-dental interaction may be an important step toward managing the aging process.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>когнитивные нарушения</kwd>
    <kwd>когнитивная дисфункция</kwd>
    <kwd>когнитивно-стоматологический синдром</kwd>
    <kwd>синдром возрастной полости рта</kwd>
    <kwd>болезнь Альцгеймера</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>cognitive impairment</kwd>
    <kwd>cognitive dysfunction</kwd>
    <kwd>cognitive-dental syndrome</kwd>
    <kwd>age-related oral syndrome</kwd>
    <kwd>Alzheimer's disease</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
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