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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Actual problems in dentistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Actual problems in dentistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Проблемы стоматологии</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2077-7566</issn>
   <issn publication-format="online">2412-9461</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">51011</article-id>
   <article-id pub-id-type="doi">10.18481/2077-7566-2022-18-2-115-122</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>ПАРОДОНТОЛОГИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>PERIODONTIC DENTISTRY</subject>
    </subj-group>
    <subj-group>
     <subject>ПАРОДОНТОЛОГИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">FUNCTIONAL STATE OF THE MICROCIRCULATORY SYSTEM IN PERIODONTAL TISSUES IN YOUNG ADULTS WITH DIFFERENT TYPES OF SMOKING</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ СИСТЕМЫ МИКРОЦИРКУЛЯТОРНОГО РУСЛА В ТКАНЯХ ПАРОДОНТА У ЛИЦ МОЛОДОГО ВОЗРАСТА ПРИ РАЗЛИЧНЫХ ВИДАХ КУРЕНИЯ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Орехова</surname>
       <given-names>Людмила Юрьевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>OREKHOVA</surname>
       <given-names>Lyudmila Yu.</given-names>
      </name>
     </name-alternatives>
     <email>prof_orekhova@mail.ru</email>
     <bio xml:lang="ru">
      <p>доктор медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Петров</surname>
       <given-names>Александр Александрович</given-names>
      </name>
      <name xml:lang="en">
       <surname>Petrov</surname>
       <given-names>Aleksandr Aleksandrovich</given-names>
      </name>
     </name-alternatives>
     <email>paa_stom@mail.ru</email>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Лобода</surname>
       <given-names>Екатерина Сергеевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>LOBODA</surname>
       <given-names>Ekaterina Sergeevna</given-names>
      </name>
     </name-alternatives>
     <email>dr_ekaterinaloboda@mail.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Малышева</surname>
       <given-names>Евгения Юрьевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>MALYSHEVA</surname>
       <given-names>Evgenia Yu.</given-names>
      </name>
     </name-alternatives>
     <email>dr_ekaterinaloboda@mail.ru</email>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Косова</surname>
       <given-names>Елена Владимировна</given-names>
      </name>
      <name xml:lang="en">
       <surname>KOSOVA</surname>
       <given-names>Elena V.</given-names>
      </name>
     </name-alternatives>
     <email>kosova.ev@bk.ru</email>
     <bio xml:lang="ru">
      <p>кандидат медицинских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of medical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Косов</surname>
       <given-names>Степан Александрович</given-names>
      </name>
      <name xml:lang="en">
       <surname>KOSOV</surname>
       <given-names>Stepan A.</given-names>
      </name>
     </name-alternatives>
     <email>kosov.s.a@yandex.ru</email>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Первый Санкт-петербургский государственный медицинский университет имени академика И. П. Павлова</institution>
     <city>Санкт-Петербург</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">First St. Petersburg State Medical University named after Academician I. P. Pavlov</institution>
     <city>Saint Peterburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Первый Санкт-Петербургский государственный медицинский университет имени ака-демика И.П. Павлова</institution>
     <city>Санкт-Петрубрг</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Pavlov First Saint Petersburg State Medical University</institution>
     <city>Saint Petersburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Первый Санкт-петербургский государственный медицинский университет имени академика И. П. Павлова</institution>
     <city>Санкт-Петербург</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">First St. Petersburg State Medical University named after Academician I. P. Pavlov</institution>
     <city>Saint Peterburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Первый Санкт-петербургский государственный медицинский университет имени академика И. П. Павлова</institution>
     <city>Санкт-Петербург</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">First St. Petersburg State Medical University named after Academician I. P. Pavlov</institution>
     <city>Saint Peterburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Первый Санкт-петербургский государственный медицинский университет имени академика И. П. Павлова</institution>
     <city>Санкт-Петербург</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">First St. Petersburg State Medical University named after Academician I. P. Pavlov</institution>
     <city>Saint Peterburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Первый Санкт-петербургский государственный медицинский университет имени академика И. П. Павлова</institution>
     <city>Санкт-Петербург</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">First St. Petersburg State Medical University named after Academician I. P. Pavlov</institution>
     <city>Saint Peterburg</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2022-08-18T21:16:26+03:00">
    <day>18</day>
    <month>08</month>
    <year>2022</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2022-08-18T21:16:26+03:00">
    <day>18</day>
    <month>08</month>
    <year>2022</year>
   </pub-date>
   <volume>18</volume>
   <issue>2</issue>
   <fpage>115</fpage>
   <lpage>122</lpage>
   <history>
    <date date-type="received" iso-8601-date="2022-06-16T00:00:00+03:00">
     <day>16</day>
     <month>06</month>
     <year>2022</year>
    </date>
   </history>
   <self-uri xlink:href="https://dental-press.ru/en/nauka/article/51011/view">https://dental-press.ru/en/nauka/article/51011/view</self-uri>
   <abstract xml:lang="ru">
    <p>Предмет исследования. Табакокурение является одним из факторов риска развития заболеваний пародонта, поэтому курящим пациентам необходимо уделять особое внимание в проведении пародонтологического лечения. Любой патологический процесс в пародонте прямо или опосредованно связан с микроциркуляторными нарушениями. Следовательно, коррекция данных нарушений будет способствовать нормализации морфофункционального статуса пародонта.&#13;
Цель — изучить функциональное состояние системы микроциркуляторного русла в тканях пародонта у лиц молодого возраста при различных видах курения.&#13;
Методология. Проведено клиническое обследование 240 пациентов с последующим разделением в зависимости от вида курения: сигареты, кальян, системы нагревания табака и электронные сигареты с жидкостями с последующим разделением на подгруппы в зависимости от стажа курения: до 1 года, от 1 года до 5 лет, более 5 лет. В дальнейшем проводилось определение индексов: упрощенный индекс гигиены полости рта по Грину–Вермиллиону (OHI-s, 1964), папиллярно-маргинально-альвеолярный индекс (PMA в модификации Parma, 1960), индекс кровоточивости SBI (Muehlemann в модификации Cowell, 1975). Для объективной оценки микроциркуляции в тканях пародонта использовался аппарат высокочастотной ультразвуковой допплерографии «Минимакс-Допплер-К» (ООО «СП-Минимакс», г. Санкт-Петербург) с последующим определением показателей средней линейной скорости кровотока (Vas) и индексов Гослинга (PI) и Пурсело (RI). В исследуемых группах динамику микроциркуляторного русла в тканях пародонта изучали в состоянии физиологического покоя, непосредственно после курения, через 15 минут, через 30 и через 60. &#13;
Результаты. Определены отличительные показатели микроциркуляции в тканях пародонта до и после различных видов курения, а также функционального состояния сосудистой архитектоники. &#13;
Выводы. Данное исследование позволяет понять, при каких видах курения наблюдаются наименьшие и наибольшие изменения микроциркуляции в тканях пародонта, что также необходимо учитывать в повседневной клинической практике при ведении курящих пациентов пародонтологического профиля молодого возраста.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Subject. Tobacco smoking is one of the risk factors of periodontal disease development; therefore, special attention should be paid to this group of patients in periodontal treatment management. Any pathological process in periodontium is directly or indirectly connected with microcirculatory disturbances. Therefore, the correction of these disturbances will promote the normalization of the periodontal morphofunctional status.&#13;
Objectives. To study functional state of the microcirculatory channel system in the periodontal tissues of the young patients with different types of smoking.&#13;
Matodology. Clinical examination of 240 patients was carried out with subsequent division into subgroups depending on the smoking type: smoking cigarettes, electronic cigarettes with liquids, tobacco heating systems and hookah with further division into subgroups depending on the smoking experience: up to 1 year, from 1 to 5 years, more than 5 years. Subsequently indices were determined: simplified index of oral hygiene according to Green–Vermillion (OHI-s, 1964), papillary-marginal-alveolar index (PMA modified by Parma, 1960), bleeding index SBI (Muehlemann modified by Cowell, 1975). For objective assessment of microcirculation in periodontal tissues we used high-frequency ultrasonic Dopplerography device &quot;Minimax-Doppler-K&quot; (LLC &quot;SP-Minimax&quot;, St. Petersburg) with subsequent determination of average linear blood flow rate (Vas) and Gosling (PI) and Purcelo (RI) indices. Microcirculatory channel dynamics in periodontal tissues of the studied groups was studied in the state of physiological rest, immediately after smoking, in 15 minutes, in 30 minutes and in 60 minutes. &#13;
Results. On the basis of the carried out research the distinctive indices of microcirculation in the periodontal tissues before and after different kinds of smoking as well as the functional state of the vascular architectonics were determined. &#13;
Conclusions. The given research allows to understand at which types of smoking the smallest and the largest changes of microcirculation in periodontal tissues are observed and that also should be taken into account in daily clinical practice when seeing young periodontal patients who smoke.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>курение</kwd>
    <kwd>микроциркуляция</kwd>
    <kwd>ультразвуковая допплерография</kwd>
    <kwd>диагностика</kwd>
    <kwd>заболевания пародонта</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>smoking</kwd>
    <kwd>microcirculation</kwd>
    <kwd>ultrasound Doppler</kwd>
    <kwd>diagnosis</kwd>
    <kwd>periodontal diseases</kwd>
   </kwd-group>
   <funding-group>
    <funding-statement xml:lang="en">-</funding-statement>
   </funding-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Karasneh J.A., Al Habashneh R.A., Marzouka N.A.S., Thornhill M.H. Effect of cigarette smoking on subgingival bacteria in healthy subjects and patients with chronic periodontitis // BMC Oral Health. - 2017;17(1):64. DOI: 10.1186/s12903-017-0359-4</mixed-citation>
     <mixed-citation xml:lang="en">Karasneh J.A., Al Habashneh R.A., Marzouka N.A.S., Thornhill M.H. Effect of cigarette smoking on subgingival bacteria in healthy subjects and patients with chronic periodontitis. BMC Oral Health. 2017;17(1):64. DOI: 10.1186/s12903-017-0359-4</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Khemiss M., Ben Fekih D., Ben Khelifa M., Ben Saad H. Comparison of periodontal status between male exclusive Narghile smokers and male exclusive cigarette smokers // Am J Mens Health. - 2019;13(2):1557988319839872. doi:10.1177/1557988319839872</mixed-citation>
     <mixed-citation xml:lang="en">Khemiss M., Ben Fekih D., Ben Khelifa M., Ben Saad H. Comparison of periodontal status between male exclusive Narghile smokers and male exclusive cigarette smokers. Am J Mens Health. 2019;13(2):1557988319839872.  doi: 10.1177/1557988319839872</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">ALHarthi S.S.Y., Natto Z.S., Midle J.B., Gyurko R., O'Neill R., Steffensen B. Association between time since quitting smoking and periodontitis in former smokers in the National Health and Nutrition Examination Surveys (NHANES) 2009 to 2012 // J Periodontol. - 2019;90(1):16-25. DOI: 10.1002/JPER.18-0183</mixed-citation>
     <mixed-citation xml:lang="en">ALHarthi S.S.Y., Natto Z.S., Midle J.B., Gyurko R., O'Neill R., Steffensen B. Association between time since quitting smoking and periodontitis in former smokers in the National Health and Nutrition Examination Surveys (NHANES) 2009 to 2012. J Periodontol. 2019;90(1):16-25. DOI: 10.1002/JPER.18-0183</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Holliday R., Chaffee B.W., Jakubovics N.S., Kist R., Preshaw P.M. Electronic Cigarettes and Oral Health // J Dent Res. - 2021;100(9):906-913. doi:10.1177/00220345211002116</mixed-citation>
     <mixed-citation xml:lang="en">Holliday R., Chaffee B.W., Jakubovics N.S., Kist R., Preshaw P.M. Electronic Cigarettes and Oral Health. J Dent Res. 2021;100(9):906-913. doi:10.1177/00220345211002116</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Hadzic S., Gojkov-Vukelic M., Pasic E., Jahic I.M., Muharemovic A., Huseinbegovic-Cengic A. The Effects of Smoking &quot;The Hookah&quot; on the Oral Health of Fourth, Fifth and Sixth-year Students of the Faculty of Dentistry in Sarajevo // Mater Sociomed. - 2020;32(3):212-217. doi:10.5455/msm.2020.32.212-217</mixed-citation>
     <mixed-citation xml:lang="en">Hadzic S., Gojkov-Vukelic M., Pasic E., Jahic I.M., Muharemovic A., Huseinbegovic-Cengic A. The Effects of Smoking &quot;The Hookah&quot; on the Oral Health of Fourth, Fifth and Sixth-year Students of the Faculty of Dentistry in Sarajevo. Mater Sociomed. 2020;32(3):212-217. doi:10.5455/msm.2020.32.212-217</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Pagano S., Negri P., Coniglio M., Bruscoli S., Di Michele A., Marchetti M.C., Valenti C., Gambelunghe A., Fanasca L., Billi M., Cianetti S., Marinucci L. Heat-not-burn tobacco (IQOS), oral fibroblasts and keratinocytes: cytotoxicity, morphological analysis, apoptosis and cellular cycle. An in vitro study // J Periodontal Res. - 2021;56(5):917-928. doi: 10.1111/jre.12888.</mixed-citation>
     <mixed-citation xml:lang="en">Pagano S., Negri P., Coniglio M., Bruscoli S., Di Michele A., Marchetti M.C., Valenti C., Gambelunghe A., Fanasca L., Billi M., Cianetti S., Marinucci L. Heat-not-burn tobacco (IQOS), oral fibroblasts and keratinocytes: cytotoxicity, morphological analysis, apoptosis and cellular cycle. An in vitro study. J Periodontal Res. 2021;56(5):917-928. doi: 10.1111/jre.12888.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Ebersole J.L., Steffen M.J., Thomas M.V., Al-Sabbagh M. Smoking-related cotinine levels and host responses in chronic periodontitis // J Periodont Res. - 2014;49(5):642-651. doi:10.1111/jre.12146</mixed-citation>
     <mixed-citation xml:lang="en">Ebersole J.L., Steffen M.J., Thomas M.V., Al-Sabbagh M. Smoking-related cotinine levels and host responses in chronic periodontitis. J Periodont Res. 2014;49(5):642-651 doi: 10.1111/jre.12146</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fang S.C., Chen S., Trachtenberg F., Rokicki S., Adamkiewicz G., Levy D.E. Validity of Self-Reported Tobacco Smoke Exposure among Non-Smoking Adult Public Housing Residents // PLoS One. - 2016;11(5):e0155024. https://doi.org/10.1371/journal.pone.0155024</mixed-citation>
     <mixed-citation xml:lang="en">Fang S.C., Chen S., Trachtenberg F., Rokicki S., Adamkiewicz G., Levy D.E. Validity of Self-Reported Tobacco Smoke Exposure among Non-Smoking Adult Public Housing Residents. PLoS One. 2016;11(5):e0155024. https://doi.org/10.1371/journal.pone.0155024</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Huang I.C., Klosky J.L., Young C.M., Murphy S.E., Krull K.K., Srivastava D., Hudson M.M., Robison L.L. Misclassification of self-reported smoking in adult survivors of childhood cancer // Pediatr Blood Cancer. - 2018;65(9):e27240. doi: 10.1002/pbc.27240.</mixed-citation>
     <mixed-citation xml:lang="en">Huang I.C., Klosky J.L., Young C.M., Murphy S.E., Krull K.K., Srivastava D., Hudson M.M., Robison L.L. Misclassification of self-reported smoking in adult survivors of childhood cancer. Pediatr Blood Cancer. 2018;65(9):e27240. doi: 10.1002/pbc.27240.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Goel K., Sharma S., Baral D.D. et al. Current status of periodontitis and its association with tobacco use amongst adult population of Sunsari district, in Nepal // BMC Oral Health. - 2021;21:66. https://doi.org/10.1186/s12903-021-01416-3</mixed-citation>
     <mixed-citation xml:lang="en">Goel K., Sharma S., Baral D.D. et al. Current status of periodontitis and its association with tobacco use amongst adult population of Sunsari district, in Nepal. BMC Oral Health 21, 66 (2021). https://doi.org/10.1186/s12903-021-01416-3</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kanmaz M., Kanmaz B., Buduneli N. Periodontal treatment outcomes in smokers: A narrative review // Tobacco Induced Diseases. - 2021;19:77. doi:10.18332/tid/142106.</mixed-citation>
     <mixed-citation xml:lang="en">Kanmaz M., Kanmaz B., Buduneli N. Periodontal treatment outcomes in smokers: A narrative review. Tobacco Induced Diseases. 2021;19:77. doi:10.18332/tid/142106.</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
