Actual problems in dentistry Actual problems in dentistry Проблемы стоматологии 2077-7566 2412-9461 50168 10.18481/2077-7566-22-18-1-19-28 ЛЕКЦИИ / ЛИТЕРАТУРНЫЕ ОБЗОРЫ LITERATURE REVIEW ЛЕКЦИИ / ЛИТЕРАТУРНЫЕ ОБЗОРЫ PATHOGENETIC PARALLELS OF OSTEOPOROSIS AND CHRONIC PERIODONTITIS. LITERATURE REVIEW ПАТОГЕНЕТИЧЕСКИЕ ПАРАЛЛЕЛИ ОСТЕОПОРОЗА И ХРОНИЧЕСКОГО ПАРОДОНТИТА. ЛИТЕРАТУРНЫЙ ОБЗОР Григорьев Сергей Сергеевич Griroriev Sergey Sergeevich sergeygrig28@gmail.com

доктор медицинских наук;

doctor of medical sciences;

 https://orcid.org/0000-0002-1838-3535 Саблина Светлана Николаевна Sablina Svetlana Nikolaevna 9122541494@mail.ru Еловикова Татьяна Михайловна Elovicova Tat'yana Mihaylovna ugma-elovik@yandex.ru

доктор медицинских наук;

doctor of medical sciences;

 Закроева Алла Геннадьевна Zakroeva Alla Gennadievna zakroeva.alla@mail.ru

доктор медицинских наук;

doctor of medical sciences;

 Фоминых Мария Игоревна Dominykh Maria Igorevna therapy.fominykh@gmail.com

кандидат медицинских наук;

candidate of medical sciences;

 Иванова Валерия Владимировна Ivanova Valeria V. 9126193222@mail.ru Уральский государственный медицинский университет Ural State Medical University Уральский государственный медицинский университет Екатеринбург Россия Ural State Medical University Ekaterinburg Russian Federation Уральский государственный медицинский университет Екатеринбург Россия Ural State Medical University Yekaterinburg Russian Federation 17 05 2022 17 05 2022 18 1 19 28 05 05 2022 https://dental-press.ru/en/nauka/article/50168/view

Предмет исследования — патогенетические параллели двух грозных заболеваний современности: остеопороза и пародонтита. Цель — анализ отечественной и зарубежной литературы о вопросах патогенетических параллелей остеопороза и пародонтальной патологии. Методология. Обзор выполнен на основании опубликованной литературы, начиная с 2016 года, с применением ключевых слов на ресурсах PubMed, еLIBRARY, Web of Science, Scopus для обобщения сведений по данной проблеме. Выводы. Согласно данным научных исследований, костная ткань орофациальной области склонна подвергаться риску остеопороза, хотя и в меньшей степени, чем кости осевого скелета, поэтому рекомендуется регулярное стоматологическое наблюдение за пациентами с остеопорозом, особенно при выявлении заболеваний пародонта на стоматологическом приеме или при выполнении комплексного плана реабилитации пациентов с восстановительной костно-пластической челюстно-лицевой хирургией. Дальнейшие контролируемые продольные исследования, вне всякого сомнения, являются полезными для изучения проблемы взаимосвязи с учетом специфичности остеогенеза для обоих заболеваний. Данный обзор литературы позволяет обновить современные представления о патогенетических параллелях остеопороза и пародонтита, оценить общие факторы риска, а также раскрыть понимание инструментов для диагностики и интерпретировать полученные результаты. Кроме того, статья поможет практикующему врачу-стоматологу на основании знаний клеточно-молекулярного строения костной ткани и патогенетических механизмов ее ремоделирования разработать персонализированную тактику сопровождения пациентов, относящихся к группе риска по двум названным заболеваниям, своевременно привлекая врачей общего профиля для междисциплинарной и комплексной терапии пациентов с пародонтальной патологией.

Subject. Parallels in the pathogenesis of two severe diseases of the modern era, osteoporosis and periodontitis. Objectives. To review domestic and international research on pathogenetic relationship between osteoporosis and periodontal pathology. Methodology. In topic generalization, the review of publications (since 2016) available on PubMed, eLIBRARY, Web of Science, Scopus by keywords is made. Conclusion. Research studies have shown that bone tissue in the orofacial region, though lesser than bones of axial skeleton, tends to develop osteoporosis. That is why patients with osteoporosis are recommended regular periodontal maintenance visits, especially when periodontal disease is diagnosed at the appointment or during the complex rehabilitation program for patients in osteoplastic and maxillofacial reconstructive surgery. Future controlled longitudinal studies may be useful in research of this relationship based on the features of osteogenesis in the both diseases. This literature review helps to develop modern views of pathogenetic relationship between osteoporosis and periodontitis, evaluate general risk factors, promote understanding of tools in the diagnostic process and interpretation of results. Moreover, with the help of this paper by knowing the cell and molecular structure of bone tissue and mechanisms of bone remodeling a dental practitioner can arrange a personalized follow-up strategy for patients in the risk group for the above two diseases timely engaging general practitioners in interdisciplinary and complex therapy of patients with periodontal pathology.

 остеопороз хронический пародонтит воспалительная деструкция костной ткани челюстных костей недостаточность витамина D osteoporosis chronic periodontitis inflammatory maxillary bone destruction vitamin D deficiency

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